北京首座天然气汽车加气站工程的施工与管理

报道北京第一座也是目前国内配套规模最大的天然气汽车加气站的工程特点,归纳该工程在施工技术管理和质量管理方面的成功经验。     

Hepatocyte-Specific Deficiency of BAP31 Amplified Acetaminophen-Induced Hepatotoxicity via Attenuating Nrf2 Signaling Activation in Mice

Liver-specific deficiency of B-cell receptor-associated protein 31 knockout mice (BAP31-LKO) and the littermates were injected with acetaminophen (APAP), markers of liver injury, and the potential molecular mechanisms were determined. In response to APAP overdose, serum aspartate aminotransferase and alanine aminotransferase levels were increased in BAP31-LKO mice than in wild-type controls, accompanied by enhanced liver necrosis. APAP-induced apoptosis and mortality were increased. Hepatic glutathione was decreased (1.60 ± 0.31 μmol/g tissue in WT mice vs. 0.85 ± 0.14 μmol/g tissue in BAP31-LKO mice at 6 h, p < 0.05), along with reduced glutathione reductase activity and superoxide dismutase; while malondialdehyde was significantly induced (0.41 ± 0.03 nmol/mg tissue in WT mice vs. 0.50 ± 0.05 nmol/mg tissue in BAP31-LKO mice for 6 h, p < 0.05). JNK signaling activation and APAP-induced hepatic inflammation were increased in BAP31-LKO mice. The mechanism research revealed that BAP31-deficiency decreased Nrf2 mRNA stability (half-life of Nrf2 mRNA decreased from ~1.3 h to ~40 min) and miR-223 expression, led to reduced nuclear factor erythroid 2-related factor 2 (Nrf2) signaling activation and antioxidant genes induction. BAP31-deficiency decreased mitochondrial membrane potentials, reduced mitochondria-related genes expression, and resulted in mitochondrial dysfunction in the liver. Conclusions: BAP31-deficiency reduced the antioxidant response and Nrf2 signaling activation via reducing Nrf2 mRNA stabilization, enhanced JNK signaling activation, hepatic inflammation, and apoptosis, amplified APAP-induced hepatotoxicity in mice.     

平板件电磁成形工艺研究

介绍电磁成形原理及其在平板件冲压工艺中的应用,分析平面螺旋线圈在加工平板件毛坯中的磁场分布,设备参数对工艺性能的影响及电磁成形工艺的优缺点。     

辽河盆地西部凹陷沙河街组三段浊积岩及其含油性

辽河盆地是一个裂谷型断陷盆地.在裂谷发育的深拗陷期(沙河街组三段),在周边剥蚀区的风化物,受重力及近源短促洪流的搬运,顺坡而下直接冲入深水湖盆中,因而形成了浊流沉积.浊积相的分布表明:可以划分为滑塌相、中心相和东梢相.主要的含油相带为滑塌相和中心相交界处,中心相及末梢相的大部分.在纵向上油层主要在砂层组的中上部,由于油层为生油岩所包围,油源充足,常形成局部高产.     

数控转台拉弯机切点跟踪轨迹生成算法

建立了拉弯过程运动关系几何模型,采用数值计算的方法推导了任意外凸模具外形曲线切点跟踪轨迹的求解算法。得出了切点坐标与转台转角的关系曲线。为拉弯机的自动切点跟踪提供了准确的控制依据。并根据轨迹上最大切线斜率最小的优化目标,以侧压轮运动范围、主缸最大允许摆角及补拉夹头与转台中心的距离为约束条件,计算出模具的最佳安装位置。运用VC编制了通用计算程序,计算结果表明：该算法稳定,适合于各种拉弯模具外形曲线,计算效率及精度高。     

俄罗斯汽机保护系统与国产机组的不同

介绍俄罗斯汽机保护在设计项目上与国产权组的区别;机组保护系统构成单元的不同,以及在线保护试验,保护自动投入,首出原因记录,两个组件中的一个故障报警等特殊功能。     

加快发展我国风力发电事业的探讨

本文介绍了风力发电的优越性和风力发电在国内外的发展状况,预测了中国风力发电的发展前景,对我国风力发电的发展提出了几点建议。     

裹包机机构动力学分析

为研究裹包机机构的动力学性能,基于Pro/E程序建立了裹包机机构的模型,并对机构进行了动力学分析。结果表明,运用仿真方法可以避免复杂的计算,缩短开发周期。为机械设计提供了强有力的工具。     

圆台薄壁结构的缓冲性能分析

为了得到圆台结构的本构模型,基于ABAQUS/Explicit程序,对圆台薄壁结构动态变形过程进行了计算仿真,得到了圆台结构载荷-位移曲线。研究方法对缓冲包装等的应用具有一定的参考价值。     

溅射富Ti-TiNi形状记忆合金薄膜

采用Ｘ射线衍射（ＸＲＤ）、透射电子显微镜（ＴＥＭ）和电阻－温度曲线等方法研究了近等原子的富ＴｉＴｉＮｉ合金薄膜的析出相和相变等特征,并对结果进行了详细讨论。