轧机主传动直流电动机通风冷却系统的设计与应用

通过实例简述了扎机主传动直流电动机通风冷却系统的风机选择原则,方法及其风机房,风机基础和通风管略的设计与应用。     

粉末冶金真空炉专用新型热电偶与在线原位校准

从粉末冶金行业的精确生产与优质高效的战略出发,简述粉末冶金行业用钨铼热电偶的特点、分类与使用。详细论述粉末冶金真空炉专用超高真空(10~5 Pa)、超高压(15 MPa)密封式热电偶及炉温均匀性测试等新型传感器。详细探讨真空炉测温准确度的影响因素:真空度、发射率、热导率、热响应时间及热电偶的插入深度、热电偶保护管的选择等;简介进口真空炉专用热电偶国产化研究,国内外温度传感器性能对比及替代进口真空炉热电偶的成功业绩。目前,对测温系统的检定,多采用分立元件法,即对构成测温系统的元件及仪表分别进行检定。此种检定方法是离线的。本文简述离线式检定方法的诸多弊端以及美国宇航标准(AMS 2750E)中,有关系统准确度校准的特点及要求。详细论述在线原位校准的最新理念,最佳的系统准确度校准方案,并开发出与其配套、行之有效的带有校准孔的热电偶及便携式在线校准仪。为了提高测温系统的准确度,建议采用在线原位校准,方便易行,现已在国内推广应用。     

Transfection of glutathione S-transferase (GST)-pi antisense complementary DNA increases the sensitivity of a colon cancer cell line to adriamycin, cisplatin, melphalan, and etoposide

The goal of this study was to demonstrate that glutathione S-transferase (GST)-pi is directly involved in the intrinsic and acquired resistance of cancer cells to anticancer drugs. To this end, GST-pi antisense cDNA was transfected into the cultured human colon cancer cell line M7609, which expresses an innately high level of GST-pi and shows intrinsic drug resistance, and into an M7609 strain with acquired resistance to Adriamycin (ADR;i.e., M7609/ADR cells). The changes in the sensitivity of these transfectants to various anticancer drugs were investigated. The intracellular concentrations of GST-pi in M7609/anti-1 cells and M7609/anti-2 cells, two clones that were established by transfection of GST-pi antisense cDNA into M7609 cells, were decreased to approximately half of those detected in the parent cells (M7609) and in the control cells transfected with vector alone (M7609/pLJ). The sensitivities of the antisense transfectants in relation to ADR, cisplatin, melphalan, and etoposide were increased -3.3-fold, 2.3-fold, 2.2-fold, and 2.1-fold, respectively, compared with those of M7609 and M7609/pLJ. On the other hand, the sensitivities of the antisense transfectants to Taxol, vincristine, 5-fluorouracil, and mitomycin C were not significantly changed. Similarly, the transfection of antisense cDNA into M7609/ADR cells resulted in the reduction of intracellular GST-pi concentration (by about half) and an increased sensitivity to ADR (4.4-fold), but no increase in 5-fluorouracil sensitivity. Thus, GST-pi is considered to be a multidrug resistance factor that is responsible for both the intrinsic and acquired resistance of cancer cells to anticancer drugs such as ADR, cisplatin, melphalan, and etoposide.     

Molecular pharmacology of voltage-dependent calcium channels

Voltage-dependent Ca2+ channels serve as the only link to transduce membrane depolarization into cellular Ca(2+)-dependent reactions. A wide variety of chemical substances that have the ability to modulate Ca2+ channels have been demonstrated both for their clinic utility and for importance in elucidating the molecular basis of various biological responses. Recently, introduction of molecular biology to pharmacology has brought a great deal of information about the molecular basis of drug action in Ca2+ channels. In this review, we attempt to overview recent progress in understanding the interactions between Ca2+ channels and their blockers, namely Ca2+ antagonists, from a molecular and structural point of view.     

纺织企业网络优化的实例分析

阐述了应用多系统集成化技术 ,对棉纺织企业中原有的初级网络系统进行优化 ,在使用WindowsNT的同时 ,可访问NetWare ,Linux ,Internet上的资源 ,使企业中一部分低档设备得到充分的利用 ,又使新的设备和信息技术在更高层次上得到了应用 .     

纳滤回收染料废水中染料的实验研究

以含盐染料废水为研究对象,应用商业化的卷式膜组件,研究了纳滤膜对染料和盐的截留特性．实验结果表明,纳滤膜对染料的截留率高达99％以上．当染料分子量高于膜截留分子量时,染料初始浓度和染料品种对染料截留率的影响甚小,盐浓度对染料截留也无明显影响,但对NaCl截留率影响显著．随料液中NaCl浓度的增加,盐截留率快速下降,当盐浓度达到3．5％时,NaCl的截留率低于25％．纳滤膜对染料的高截留率和对NaCl的低截留率,使得应用纳滤技术从含盐染料废水中回收染料具有较好的经济性和可行性．     

Contourlet变换在图像检索中的应用

利用 Contourlet 变换良好的稀疏特性及其能准确地捕获图像中边缘信息的特性,分析了纹理图像Contourlet系数的统计特征,提出了一种滤波算法。该算法根据纹理图像Contourlet系数分布的特点,采用高斯模型对其进行精确拟合提取纹理特征,针对各子带数据的离散程度进行加权处理,为分类能力强的特征量赋予较大的权值,并加入在低频子带上提取的灰度—平滑共生矩阵统计量,来形成最终的特征向量,以两幅图像不同特征向量间的加权欧氏距离作为图像的相似度进行检索。仿真实验结果表明,该方法在检索效果上有一定的优越性。     

虚拟现实的发展及在机器人系统中的应用与研究

本文全面回顾了虚拟现实技术的发展,及其在机器 人领域的应用与研究;分析了目前所面临的问题及主要研究方向．     

基于元搜索引擎的个性化Web信息采集

为了减少传统Web采集系统网络资源的耗费,并增强其个性化支持,结合用户兴趣向量模型,将元搜索引擎技术应用到Web信息采集领域中,设计一个基于元搜索引擎的个性化Web信息采集系统.该系统通过调用成员搜索引擎发现与用户兴趣相关的目标Web站点,通过爬虫程序采集目标站点上的Web页面内容.在发现兴趣站点方面更具有针对性,能有效减少爬虫的数量.重点研究了系统的体系结构、个性化Web采集的工作流程,最后给出了该系统的应用场合.     

Two-Parameter Thermal Lattice BGK Model with a Controllable Prandtl Number

In this paper, two time relaxation parameters are introduce to a thermal lattice BGK, model to make its Prandtl number controllable. The dependency of the Prandtl number on the two parameters is derived. Numerical measurement of the transport coefficients is used to demonstrate the validity of the method. Furthermore, two examples of convective heat transfer are calculated, with one to show the effectiveness, and the other to show the breakdown of the two-parameter formulation under different conditions.