Determination of sequence length distribution in SBR by ozonolysis-g.p.c. method

Sequence distribution of styrene-butadiene copolymer (SBR) was investigated by ozonolysis-g.p.c. All the double bonds of butadiene units in SBR were cleaved by ozonolysis in methylene chloride at ?30°C, followed by reduction degradation to alcohol with lithium aluminium hydride. The g.p.c. of the ozonolysis products observed with a u.v.-detector showed the peaks corresponding to styrene sequences and styrene-1,2 sequences. Hot- and cold-emulsion SBR samples contained short sequences consisting of 1 to 4 styrene units and 1,2 styrene units respectively. The average sequence length of cold-emulsion SBR was slightly longer than that of hot-emulsion SBR. A partial block SBR prepared by solution polymerization contained short styrene sequences of 1 to 5 units and long sequences having a broad distribution of $\text{M}{}_{\mathrm{w}}\text{M}{}_{\mathrm{n}}\text{= 1.6}$ with the maximum around 35 units. The styrene sequences containing the 1,2 unit was scarcely observed in this sample.     

Design,Synthesis, and Biological Evaluation of Lysine Demethylase 5 C Degraders

Lysine demethylase 5 C (KDM5C) controls epigenetic gene expression and is attracting great interest in the field of chemical epigenetics. KDM5C has emerged as a therapeutic target for anti-prostate cancer agents, and recently we identified triazole 1 as an inhibitor of KDM5C. Compound 1 exhibited highly potent KDM5C-inhibitory activity in in vitro enzyme assays, but did not show strong anticancer effects. Therefore, a different approach is needed for the development of anticancer agents targeting KDM5C. Here, we attempted to identify KDM5C degraders by focusing on a protein-knockdown strategy. Compound 3 b , which was designed based on compound 1 , degraded KDM5C and inhibited the growth of prostate cancer PC-3 cells more strongly than compound 1 . These findings suggest that KDM5C degraders are more effective as anticancer agents than compounds that only inhibit the catalytic activity of KDM5C.     

Short‐circuit phenomenon through hot gas ejected from molded case circuit breakers during high current interruption process and prevention of its occurrence

An experimental investigation on short‐circuit phenomenon through ejected hot gas between source‐side terminals in molded case circuit breakers (MCCBs) was performed. The rate of occurrence of the short‐circuit phenomenon was found to increase with the peak value of the breaking current and with the order of the breaking test. The conductance of the ejected hot gas was also found to rise with the peak value of the breaking current and with the order of the breaking test. These results indicate that the hot gas of high conductance is the cause of the short‐circuit phenomenon. Some effective means were taken in the MCCB to reduce the conductance of the hot gas. Decreasing the conductance of the hot gas successfully prevented the occurrence of short‐circuit phenomenon. © 2000 Scripta Technica, Electr Eng Jpn, 132(1): 22–29, 2000     

Effect of tube bundles on nucleate boiling and critical heat flux

In order to elucidate boiling heat transfer characteristics for each tube and the critical heat flux (CHF) for tube bundles, an experimental investigation of pool and flow boiling of Freon-113 at 0.1 MPa was performed using two typical tube arrangements. A total of fifty heating tubes of 14 mm diameter, equipped with thermocouples and cartridge heaters, were arrayed at pitches of 18.2 and 21.0 mm to simulate both square in-line and equilateral staggered bundles. For the flow boiling tests the same bundles as were used in pool boiling were installed in a vertical rectangular channel, to which the fluid was supplied with an approach velocity varying from 0.022 to 0.22 m/s. It was found in this study that the boiling heat transfer coefficient of each tube in a bundle was higher than that for an isolated single tube in pool boiling. This enhancement increases for tubes at higher locations, but decreases as heat flux is increased. At heat fluxes exceeding certain values, the heat transfer coefficient becomes the same as that for an isolated tube. As the heat flux approaches the CHF, flow pulsations occurred in the pool boiling experiments although the heat transfer coefficient was invariant even under this situation. The approach velocity has an appreciable effect on heat transfer up to a certain level of heat flux. In this range of heat flux, the heat transfer coefficient exceeds the values observed for pool boiling. An additive method with two contributions, i.e., single phase convection and boiling, was used to predict the heat transfer coefficient for bundles. The predicted results showed reasonable agreement with the measured results. The critical heat flux in tube bundles tended to increase as more bubbles were rising through the tube clearance. © 1998 Scripta Technica, Heat Trans Jpn Res, 27(4): 312–325, 1998     

Experimental investigation of falling film evaporation on horizontal tubes

This paper presents the results of an experimental investigation relating to heat transfer during evaporation of thin liquid films falling over horizontal tubes. Experiments were conducted using 25 mm o.d. copper tubes heated by internal electrical cartridge heaters so that a uniform heat flux was generated on the outside tube surface. Five heated tubes were arrayed on a vertical plane with a pitch of 50 mm. Freon R-11 preheated to the saturation temperature at 0.2 MPa was supplied to the topmost heated tube through feeding tubes. Heat transfer characteristics on each heated tube were clarified in a range of film Reynolds number from 10 to 2000 and the measured data are presented in the form of correlations. Deterioration of heat transfer due to film break down was also considered. © 1999 Scripta Technica, Inc. Heat Trans Jpn Res, 27(8): 609–618, 1998     

Supercritical hydrothermal synthesis and in situ organic modification of indium tin oxide nanoparticles using continuous-flow reaction system

ITO nanoparticles were synthesized hydrothermally and surface modified in supercritical water using a continuous flow reaction system. The organic modification of the nanoparticles converted the surface from hydrophilic to hydrophobic, making the modified nanoparticles easily dispersible in organic solvent. The addition of a surface modifier into the reaction system impacted the crystal growth and particle size as well as dispersion. The particle size was 18 nm. Highly crystalline cubic ITO with a narrow particle size distribution was obtained. The advantages of short reaction time and the use of a continuous reaction system make this method suitable for industrial scale synthesis.     

Effect of plate position and size for self-induced flow oscillation of underexpanded supersonic jet impinging on perpendicular plate

When the underexpanded supersonic jet impinges on the obstacle, it is well known that the self-induced flow oscillation occurs at the specific condition of the pressure ratio in the flowfield, the position of an obstacle and so on. This oscillation is related with the noise problems of aeronautical and other industrial engineering so that the characteristic and the mechanism of self-induced flow oscillation have to be cleared to control the various noise problems. But, it seems that the characteristics of t...     

Calculation of effective delayed neutron fraction with Monte Carlo perturbation techniques

New methods are proposed to estimate the effective delayed neutron fraction β_eff in Monte Carlo calculations: the eigenvalue methods jointly used with the differential operator sampling and correlated sampling techniques. In particular, the eigenvalue method with the differential operator sampling technique has a distinct feature that it theoretically gives an exact β_eff value. To verify the proposed methods, Monte Carlo calculations are performed for several systems with simple geometry. It is found that the results obtained with the proposed methods agree with the reference deterministic results within sufficiently small statistical uncertainties. The indirect perturbed source effect must be taken into account to estimate an exact β_eff value.     

Thick films for multilayer substrates

Abstract

Low temperature fired ceramics based on alumina/glass added oxide ceramics have been developed and are being used by several companies as substrates for high density assembled modular packaging.^1–3 The features of low temperature fireable substrates are the cofireability with highly conductive metals such as Ag, Ag-Pd, or Cu, and the cofireability with other passive component materials for L, C, R and relatively low dielectric constant elements. But most of these substrates have the disadvantage that their thermal expansion coefficient is not perfectly compatible with Si or GaAs. This paper reports the results of a newly developed cordierite/glass based substrate employing Cu as the surface and internal conductors and having the freedom of tuning the thermal expansion coefficient by changing the composition. The ceramic composition with adjustable thermal expansion coefficient value of 3 to 7 ppm/°C can be manufactured and easily matched with the thermal expansion coefficient of Si or GaAs without a big change of electrical performance.     

Thermodynamic,transport and radiation properties of high-temperature CF3I and transient conductance of residual arc sustained in axial CF3I flow

The present paper reports fundamental properties of CF₃I under high-temperature conditions to find out the usefulness of CF₃I as an arc-quenching gas. Firstly, particle compositions of CF₃I were theoretically calculated in a temperature range from 300 to 30 000 K. Secondly, thermodynamic, transport and radiation properties of the CF₃I were also obtained for pressures 0.1–1.0 MPa. Finally, the transient process of a conductance of a residual arc in CF₃I was derived to compare with those in other arc-quenching gases. In addition, an arc extinguishing capability of CF₃I in a thermal re-ignition region was derived to find out whether CF₃I shows a higher capability than CO₂, N₂ and air. © 2006 Institute of Electrical Engineers of Japan. Published by John Wiley & Sons, Inc.