THE MIGRATION OF IMPURITY ATOMS AND HYDROGEN EMBRITTLEMENT CRACKING

<正> 一般认为裂纹材料的氢脆开裂是一个和氢原子扩散有关的过程。在负载条件下,氢原子将从四周扩散到裂纹尖端高应力区,当局部浓度达到临界值即起始开裂。开裂的每一步只能跃进一定距离,当裂纹扩展到氢含量很低的区域便暂时停止,然后,氢原子又再扩散聚集,如此往复,裂纹以不连续开裂方式向前扩展。     

TA15合金的热变形行为及加工图

研究了TA15合金的热模拟压缩实验。结果表明：变形温度的升高和应变速率的减小使峰值应力和稳态应力显著降低，变形温度会影响进入稳态流动所需变形量。以热模拟压缩实验为基础，建立的加工图表明：TA15合金高温变形时存在2个非稳定区域，一个是变形温度1300K以上和应变速率10．0s^-1以上的区域，另一个是变形温度1200K以下和应变速率0．006s^-1～1．995s^-1之间的区域。同时，建立的TA15合金高温变形时的流动应力模型表征了变形温度、应变速率和变形程度对流动应力的影响，模型的计算精度较高。     

酿酒酵母中基于外壳蛋白复合物Ⅱ囊泡的蛋白分泌调控机制的研究进展

在酿酒酵母中,外壳蛋白复合物Ⅱ(COPⅡ)包裹的囊泡是蛋白质从内质网转运至高尔基体的媒介,其中COPⅡ囊泡介导的运输是蛋白分泌途径中至关重要的一步.COPⅡ囊泡的运输包括囊泡形成、出芽、束缚和融合.整个过程需要外壳蛋白亚基、三磷酸鸟苷(GTP)、束缚因子等多种组分的参与,且部分组分之间存在的相互作用确保了蛋白质的正确运输.研究对COPⅡ囊泡整个运输过程中受到的外壳亚基组装、蛋白质捕获以及膜融合等一系列调控机制进行较系统综述,有望为改造酿酒酵母中蛋白分泌途径提供参考.     

基于压缩感知理论和二阶微分法的贯通式同相AT牵引供电系统牵引网输电线路单端保护方法

贯通式同相牵引供电系统能彻底解决电分相及负序问题,是目前高速铁路研究的重要方向.压缩感知技术在突破奈奎斯特采样定理对采样个数要求的同时能增强信号时聚性,并对故障暂态信号进行降噪.二阶微分法可以放大故障特征,解决高阻接地故障时故障分量过小而导致保护拒动的问题.提出用压缩感知技术对故障电流的线模信号进行压缩重构,再由二阶微分法处理压缩感知重构出的故障电流线模信号得到其首波头的幅值,将该幅值与预设阈值比较进而判断出故障位置的保护方法.利用PSCAD/EMTDC平台搭建贯通式同相AT牵引供电系统模型,通过改变故障位置、故障初始角及过渡电阻进行仿真实验,实验结果验证了该保护方法的有效性.     

高海拔变电站蓄电池及UPS容量选择及修正

高海拔地区环境温度、空气密度及气压低,在选择变电站站用蓄电池及UPS容量时应进行必要的修正,以满足变电站的用电需求。结合阿里与藏中联网工程的某500 k V变电站项目,对高海拔变电站蓄电池及UPS容量选择进行了探讨分析,希望能为类似工程提供参考。     

基于主动频率注入的直流微电网功率分配策略

针对传统下垂控制在母线电压稳定和输出电流精确分配上存在矛盾的问题,提出了一种基于交流小信号注入的直流微电网自适应虚拟阻抗控制策略.首先,在变换器输出直流电压上叠加低频交流小信号,使注入信号频率与输出电流产生下垂特性,并利用交流有功功率自适应调节虚拟阻抗.然后,设计了切换环节,稳态时切换为下垂控制,利用控制频率得到的稳态虚拟阻抗作为下垂系数,在维持电流精确分配的情况下,消除了交流信号对电能质量的影响,提高了系统的可靠性和可扩展性.最后,通过仿真验证了该方法的有效性.     

配位负载法制备CoS2/AOCF复合材料及其电催化析氢性能

以硫酸钴、硫代硫酸钠、硫和偕胺肟化聚丙烯腈纤维(AOCF)为原料,采用配位负载法制备了CoS2/AOCF复合材料,采用SEM、XRD、TEM、XPS和BET对CoS2/AOCF进行物相分析和形貌表征,并对CoS2/AOCF复合材料的电催化析氢性能进行了测试.结果表明,AOCF链上—OH、—NH2与Co(Ⅱ)的配位作用极大地提高了活性组分CoS2的比表面积,改变了活性组分的晶体结构,增大了有效活性位点的数量.CoS2/AOCF在10 mA/cm2的电流密度下过电势为92 mV,Tafel斜率仅为43 mV/dec,具有良好的析氢稳定性,展现了优异的电化学性能.     

汽车涂装集中输调漆系统的发展现状

概述了汽车涂装集中输调漆系统的发展现状,描述了集中输调漆系统的一般构成,重点介绍了电动泵智能油漆循环系统和走珠式快速换色系统.     

Simulated Microgravity Inhibits the Proliferation of Chang Liver Cells by Attenuation of the Major Cell Cycle Regulators and Cytoskeletal Proteins

Simulated microgravity (SMG) induced the changes in cell proliferation and cytoskeleton organization, which plays an important factor in various cellular processes. The inhibition in cell cycle progression has been considered to be one of the main causes of proliferation inhibition in cells under SMG, but their mechanisms are still not fully understood. This study aimed to evaluate the effects of SMG on the proliferative ability and cytoskeleton changes of Chang Liver Cells (CCL-13). CCL-13 cells were induced SMG by 3D clinostat for 72 h, while the control group were treated in normal gravity at the same time. The results showed that SMG reduced CCL-13 cell proliferation by an increase in the number of CCL-13 cells in G0/G1 phase. This cell cycle phase arrest of CCL-13 cells was due to a downregulation of cell cycle-related proteins, such as cyclin A1 and A2, cyclin D1, and cyclin-dependent kinase 6 (Cdk6). SMG-exposed CCL-13 cells also exhibited a downregulation of α-tubulin 3 and β-actin which induced the cytoskeleton reorganization. These results suggested that the inhibited proliferation of SMG-exposed CCL-13 cells could be associate with the attenuation of major cell cycle regulators and main cytoskeletal proteins.     

Design,Synthesis, and Biological Evaluation of Novel 6H-Benzo[c]chromen-6-one Derivatives as Potential Phosphodiesterase II Inhibitors

Urolithins (hydroxylated 6H-benzo[c]chromen-6-ones) are the main bioavailable metabolites of ellagic acid (EA), which was shown to be a cognitive enhancer in the treatment of neurodegenerative diseases. As part of this research, a series of alkoxylated 6H-benzo[c]chromen-6-one derivatives were designed and synthesized. Furthermore, their biological activities were evaluated as potential PDE2 inhibitors, and the alkoxylated 6H-benzo[c]chromen-6-one derivative 1f was found to have the optimal inhibitory potential (IC₅₀: 3.67 ± 0.47 μM). It also exhibited comparable activity in comparison to that of BAY 60-7550 in vitro cell level studies.