全文获取类型
收费全文 | 8999篇 |
免费 | 603篇 |
国内免费 | 21篇 |
专业分类
电工技术 | 125篇 |
综合类 | 18篇 |
化学工业 | 2339篇 |
金属工艺 | 170篇 |
机械仪表 | 207篇 |
建筑科学 | 321篇 |
矿业工程 | 36篇 |
能源动力 | 223篇 |
轻工业 | 402篇 |
水利工程 | 68篇 |
石油天然气 | 28篇 |
无线电 | 758篇 |
一般工业技术 | 2286篇 |
冶金工业 | 981篇 |
原子能技术 | 78篇 |
自动化技术 | 1583篇 |
出版年
2023年 | 153篇 |
2022年 | 374篇 |
2021年 | 418篇 |
2020年 | 285篇 |
2019年 | 246篇 |
2018年 | 301篇 |
2017年 | 255篇 |
2016年 | 349篇 |
2015年 | 297篇 |
2014年 | 438篇 |
2013年 | 550篇 |
2012年 | 547篇 |
2011年 | 623篇 |
2010年 | 423篇 |
2009年 | 412篇 |
2008年 | 433篇 |
2007年 | 416篇 |
2006年 | 324篇 |
2005年 | 252篇 |
2004年 | 222篇 |
2003年 | 201篇 |
2002年 | 191篇 |
2001年 | 122篇 |
2000年 | 113篇 |
1999年 | 119篇 |
1998年 | 193篇 |
1997年 | 154篇 |
1996年 | 105篇 |
1995年 | 83篇 |
1994年 | 73篇 |
1993年 | 90篇 |
1992年 | 53篇 |
1991年 | 50篇 |
1990年 | 50篇 |
1989年 | 37篇 |
1988年 | 44篇 |
1987年 | 40篇 |
1986年 | 34篇 |
1985年 | 42篇 |
1984年 | 37篇 |
1983年 | 32篇 |
1982年 | 27篇 |
1981年 | 27篇 |
1980年 | 23篇 |
1979年 | 19篇 |
1978年 | 28篇 |
1977年 | 24篇 |
1976年 | 60篇 |
1975年 | 27篇 |
1971年 | 17篇 |
排序方式: 共有9623条查询结果,搜索用时 15 毫秒
91.
In this paper we study small depth circuits that contain threshold gates (with or without weights) and parity gates. All circuits we consider are of polynomial size. We prove several results which complete the work on characterizing possible inclusions between many classes defined by small depth circuits. These results are the following:
相似文献
1. | A single threshold gate with weights cannot in general be replaced by a polynomial fan-in unweighted threshold gate of parity gates. |
2. | On the other hand it can be replaced by a depth 2 unweighted threshold circuit of polynomial size. An extension of this construction is used to prove that whatever can be computed by a depthd polynomial size threshold circuit with weights can be computed by a depthd+1 polynomial size unweighted threshold circuit, whered is an arbitrary fixed integer. |
3. | A polynomial fan-in threshold gate (with weights) of parity gates cannot in general be replaced by a depth 2 unweighted threshold circuit of polynomial size. |
92.
93.
Asymmetrically cracked specimens fail with considerably less ductility than symmetrically cracked ones, due to the crack progressing along a shear band into pre-damaged material. A formulation for the accumulation of damage ahead of an asymmetric crack is presented, based on strain increments following a power law relation. These results are integrated both numerically and approximately.The crack growth per unit displacement increases approximately as the logarithm of the total crack advance per inclusion spacing , and varies inversely as the critical fracture strain c. This provides a basis for predicting large-scale, fully plastic fracture from asymmetric weld defects, using small-scale laboratory specimens.
Résumé Les éprouvettes fissurées de manière asymétrique se rompent avec beaucoup moins de ductilité que celles qui sont fissurées de manières symétrique, en raison du fait que la fissure se développe suivant une bande de cisaillement dans un matériau préendommagé. On Présente une formulation de l'accumulation du dommage en avant d'une fissure asymétrique, en se basant sur des gradients de déformations répartis selon une loi quadratique. L'interprétation des résultats est effectuée par voie numérique et par approximation.On constate que le croissance d'une fissure par unité de déplacement est sensiblement proportionnelle au logarithme de l'avancement total de la fissure rapporté à l'espacement entre deux inclusions , et en raison inverse de la déformation critique à la rupture c. Ceci fournt une base pour prédire une rupture à plus grande échelle et en conditions tout à fait plastiques, qui résulteront de défauts de soudage asymétriques, et ce en utilisant des éprouvettes réduites de laboratoire.相似文献
94.
The Kirchhoff approximation is used to show that the time domain impulse response of an isolated flat crack can be given a simple geometrical interpretation in terms of the derivative of a projected length function. For an elliptical crack, this derivative can be obtained explicitly to yield the two edge-diffracted waves which originate from the flashpoints of the crack. An explicit coordinate invariant expression is obtained from this elliptical crack solution which relates the time difference, t, between the arrival of these edge-diffracted waves and the crack size and orientation. Previously, we have proposed that this expression, together with t measurements in different scattering directions, could be used in a regression analysis as the basis for performing a constrained inversion of crack scattering data (i.e., where we attempt to obtain the best equivalent flat elliptical crack that fits the scattering measurements). Here we will demonstrate some results of applying the proposed algorithm using noisy synthetic data. The sensitivity of the results to both, number of measurements and transducer orientation, will be discussed. 相似文献
95.
Alexander L. Fetter 《Journal of Low Temperature Physics》1987,67(1-2):17-25
A variational technique is used to analyze the deformed texture of superfluid3He-A in a narrow slab subject to a perpendicular magnetic field. Specific predictions are made for the anisotropy parameters
and
, averaged across the width. 相似文献
96.
The problem of path planning for an automaton moving in a two-dimensional scene filled with unknown obstacles is considered. The automaton is presented as a point; obstacles can be of an arbitrary shape, with continuous boundaries and of finite size; no restriction on the size of the scene is imposed. The information available to the automaton is limited to its own current coordinates and those of the target position. Also, when the automaton hits an obstacle, this fact is detected by the automaton's tactile sensor. This information is shown to be sufficient for reaching the target or concluding in finite time that the target cannot be reached. A worst-case lower bound on the length of paths generated by any algorithm operating within the framework of the accepted model is developed; the bound is expressed in terms of the perimeters of the obstacles met by the automaton in the scene. Algorithms that guarantee reaching the target (if the target is reachable), and tests for target reachability are presented. The efficiency of the algorithms is studied, and worst-case upper bounds on the length of generated paths are produced.Supported in part by the National Science Foundation Grant DMC-8519542. 相似文献
97.
Marie Burns Lennard Ostendorf Robert Biesen Andreas Grützkau Falk Hiepe Henrik E. Mei Tobias Alexander 《International journal of molecular sciences》2021,22(5)
Given its uniformly high expression on plasma cells, CD38 has been considered as a therapeutic target in patients with systemic lupus erythematosus (SLE). Herein, we investigate the distribution of CD38 expression by peripheral blood leukocyte lineages to evaluate the potential therapeutic effect of CD38-targeting antibodies on these immune cell subsets and to delineate the use of CD38 as a biomarker in SLE. We analyzed the expression of CD38 on peripheral blood leukocyte subsets by flow and mass cytometry in two different cohorts, comprising a total of 56 SLE patients. The CD38 expression levels were subsequently correlated across immune cell lineages and subsets, and with clinical and serologic disease parameters of SLE. Compared to healthy controls (HC), CD38 expression levels in SLE were significantly increased on circulating plasmacytoid dendritic cells, CD14++CD16+ monocytes, CD56+ CD16dim natural killer cells, marginal zone-like IgD+CD27+ B cells, and on CD4+ and CD8+ memory T cells. Correlation analyses revealed coordinated CD38 expression between individual innate and memory T cell subsets in SLE but not HC. However, CD38 expression levels were heterogeneous across patients, and no correlation was found between CD38 expression on immune cell subsets and the disease activity index SLEDAI-2K or established serologic and immunological markers of disease activity. In conclusion, we identified widespread changes in CD38 expression on SLE immune cells that highly correlated over different leukocyte subsets within individual patients, but was heterogenous within the population of SLE patients, regardless of disease severity or clinical manifestations. As anti-CD38 treatment is being investigated in SLE, our results may have important implications for the personalized targeting of pathogenic leukocytes by anti-CD38 monoclonal antibodies. 相似文献
98.
Oleksandr Gryshkov Vitalii Mutsenko Dmytro Tarusin Diaa Khayyat Ortwin Naujok Ekaterina Riabchenko Yuliia Nemirovska Arseny Danilov Alexander Y. Petrenko Birgit Glasmacher 《International journal of molecular sciences》2021,22(6)
Alginate as a versatile naturally occurring biomaterial has found widespread use in the biomedical field due to its unique features such as biocompatibility and biodegradability. The ability of its semipermeable hydrogels to provide a favourable microenvironment for clinically relevant cells made alginate encapsulation a leading technology for immunoisolation, 3D culture, cryopreservation as well as cell and drug delivery. The aim of this work is the evaluation of structural properties and swelling behaviour of the core-shell capsules for the encapsulation of multipotent stromal cells (MSCs), their 3D culture and cryopreservation using slow freezing. The cells were encapsulated in core-shell capsules using coaxial electrospraying, cultured for 35 days and cryopreserved. Cell viability, metabolic activity and cell–cell interactions were analysed. Cryopreservation of MSCs-laden core-shell capsules was performed according to parameters pre-selected on cell-free capsules. The results suggest that core-shell capsules produced from the low viscosity high-G alginate are superior to high-M ones in terms of stability during in vitro culture, as well as to solid beads in terms of promoting formation of viable self-assembled cellular structures and maintenance of MSCs functionality on a long-term basis. The application of 0.3 M sucrose demonstrated a beneficial effect on the integrity of capsules and viability of formed 3D cell assemblies, as compared to 10% dimethyl sulfoxide (DMSO) alone. The proposed workflow from the preparation of core-shell capsules with self-assembled cellular structures to the cryopreservation appears to be a promising strategy for their off-the-shelf availability. 相似文献
99.
Alexander Kutschera Ursula Schombel Dominik Schwudke Stefanie Ranf Nicolas Gisch 《International journal of molecular sciences》2021,22(6)
Lipopolysaccharide (LPS), the major component of the outer membrane of Gram-negative bacteria, is important for bacterial viability in general and host–pathogen interactions in particular. Negative charges at its core oligosaccharide (core-OS) contribute to membrane integrity through bridging interactions with divalent cations. The molecular structure and synthesis of the core-OS have been resolved in various bacteria including the mammalian pathogen Pseudomonas aeruginosa. A few core-OS structures of plant-associated Pseudomonas strains have been solved to date, but the genetic components of the underlying biosynthesis remained unclear. We conducted a comparative genome analysis of the core-OS gene cluster in Pseudomonas syringae pv. tomato (Pst) DC3000, a widely used model pathogen in plant–microbe interactions, within the P. syringae species complex and to other plant-associated Pseudomonas strains. Our results suggest a genetic and structural conservation of the inner core-OS but variation in outer core-OS composition within the P. syringae species complex. Structural analysis of the core-OS of Pst DC3000 shows an uncommonly high phosphorylation and presence of an O-acetylated sugar. Finally, we combined the results of our genomic survey with available structure information to estimate the core-OS composition of other Pseudomonas species. 相似文献
100.
Svetlana V. Klinova Boris A. Katsnelson Ilzira A. Minigalieva Oksana P. Gerzen Alexander A. Balakin Ruslan V. Lisin Ksenia A. Butova Salavat R. Nabiev Oleg N. Lookin Leonid B. Katsnelson Larisa I. Privalova Daniil A. Kuznetsov Vladimir Ya. Shur Ekaterina V. Shishkina Oleg H. Makeev Irene E. Valamina Vladimir G. Panov Marina P. Sutunkova Larisa V. Nikitina Yuri L. Protsenko 《International journal of molecular sciences》2021,22(7)
Subchronic intoxication was induced in outbred male rats by repeated intraperitoneal injections with lead oxide (PbO) and/or cadmium oxide (CdO) nanoparticles (NPs) 3 times a week during 6 weeks for the purpose of examining its effects on the contractile characteristics of isolated right ventricle trabeculae and papillary muscles in isometric and afterload contractions. Isolated and combined intoxication with these NPs was observed to reduce the mechanical work produced by both types of myocardial preparation. Using the in vitro motility assay, we showed that the sliding velocity of regulated thin filaments drops under both isolated and combined intoxication with CdO–NP and PbO–NP. These results correlate with a shift in the expression of myosin heavy chain (MHC) isoforms towards slowly cycling β–MHC. The type of CdO–NP + PbO–NP combined cardiotoxicity depends on the effect of the toxic impact, the extent of this effect, the ratio of toxicant doses, and the degree of stretching of cardiomyocytes and muscle type studied. Some indices of combined Pb–NP and CdO–NP cardiotoxicity and general toxicity (genotoxicity included) became fully or partly normalized if intoxication developed against background administration of a bioprotective complex. 相似文献