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91.
Yi Jin Chieko Toeda Takeo Kawaguchi Toshinobu Seki Kazuhiko Juni 《Drug development and industrial pharmacy》1996,22(7):653-658
Permeation of zidovudine (3'-azido-3'-deoxythymidine, AZT) and probenecid from oily bases containing an alcohol through rat skin was examined. Isopropyl myristate (IPM), as an oily vehicle, showed a penetration enhancing effect for AZT and probenecid. Ethanol, n-propanol, and n-butanol were used as additives in IPM and were examined for their own permeation and the enhancing effect on the permeation of AZT and probenecid. The skin permeation of AZT and probenecid from IPM was enhanced by addition of the alcohol in IPM. The degree of the enhancement was decreased with increasing lipophilicity of the alcohol used. me permeation rate of the drug from those systems was shown to be governed by penetration-enhancing effects of the oily base and alcohol, and the penetration of the alcohol itself through the skin. 相似文献
92.
93.
The problem of joint estimation of time delay and Doppler shift is considered from the point of view of the Wigner distribution of the signal. A very efficient method of obtaining the optimum signal with minimum estimation error based on the convexity of the design region is developed. Practical applications, however, require the signal to satisfy other constraints which present complications in acquiring the optimum signal. A design approach based on the method of simulated annealing is suggested to solve for the optimum signal under constraints. The performance of the signals so obtained is evaluated and compared with that of signals obtained by synthesis 相似文献
94.
Capacity has always been a major concern in wireless networks. This letter studies the impact of mobility on the overall system capacity in wireless cellular networks. In this letter, we present a simple system model which we developed to capture the inherent relationships among system capacity, new call blocking probability, handoff dropping probability, call terminating probability, and bandwidth utilization rate. We investigate the complex relationship between mobility and capacity‐related parameters. Through simulation, we demonstrate that mobility has a significant impact on capacity and is reversely proportional to the bandwidth reserved for handoff traffic. 相似文献
95.
空调系统应用于普通房间可能引起空调病 ,应用于医院时此问题将更为突出 ,本文对此类建筑在空调系统设计中应重视的有关问题进行了初步探讨 相似文献
96.
97.
98.
铝电解槽磁流体稳定性有限元分析 总被引:2,自引:0,他引:2
本文采用有限元法求解分层磁流体小扰动方程系统特征值,研究铝电解槽稳定性。研究结果表明,在没有电磁力时,铝液表面波动(内波)是稳定的。存在电磁力时,它会激发铝液表面波动的某些低频长波分量不稳定性,高频短波不受影响。被激发的不稳定波动频率和扰动增长率与电流密度,磁感应强度垂直分量,铝电解槽长宽比,电解质和铝液的密度差,厚度等因素密切相关。减少电流密度,磁感应强度,增加电极距离和铝液厚度可以提高铝电解槽的稳定性。这对铝电解槽优化设计和在线控制有重要意义。 相似文献
99.
Spectral slope (S), describing the exponential decrease of the absorption spectrum over a given wavelength range, is an important parameter in the study of of chromophoric dissolved organic matter (CDOM) dynamics, and also an essential input parameter in remote sensing models. Furthermore, S is often used as a proxy for CDOM composition, including the ratio of fulvic to humic acids and molecular weight. The relative broad range in S values reported in the literature can be explained by the different spectral ranges and fitting methods used. A single exponential model is used to fit the S values for 17 investigations involving 458 samples in Lake Taihu from January to October in 2004. The average S value was 15.18 ± 1.39 μm−1 for the range of 280–500 nm, which fell within the range reported in the literature. The frequency distribution of S value basically obeyed a normal distribution. Significant differences in S values between summer and other seasons showed that phytoplankton degradation was one of the important sources of CDOM in summer, whereas CDOM mainly came from the river input in other seasons. Furthermore, the estimated S value decreased with increasing wavelength range used in regression. The maximum and minimum values derived from the regression were 17.89 ± 1.25 μm−1 and 13.62 ± 2.11 μm−1 for the wavelength ranges of 280–380 nm and 400–500 nm, respectively, a decrease of 23.9%. S values significantly decreased with the increase of CDOM absorption coefficients. CDOM absorption coefficients could be more appropriately estimated from exponential model introducing the variation of S with absorption coefficients, making them useful for a remote sensing bio-optical model of Lake Taihu. DOC-specific absorption coefficient a*(λ) and the parameter M describing molecular size of the humic molecules could also be used as a proxy for the sources and types of CDOM. A general relationship was found between S and a*(λ), and M values. S increased with the decrease of DOC-specific absorption coefficient and the increase of M corresponding to the decrease of molecular weight. 相似文献
100.
Jin Wang Marculescu A. Jingshi Li Vorreau P. Tzadok S. Ben Ezra S. Tsadka S. Freude W. Leuthold J. 《Photonics Technology Letters, IEEE》2007,19(24):1955-1957
A technique to overcome pattern dependence in semiconductor-optical-amplifier-based wavelength converters is presented. The technique is based on a careful selection of red- and blue-shifted spectral components having complementary pattern effects in the output spectrum of a wavelength-converted signal. Significant signal quality improvements are reported at a bit rate of 40 Gb/s. 相似文献