采用误差传递基函数匹配追踪的测量船误差溯源技术

针对航天测量船外弹道测控系统中影响测控精度的误差源众多、作用机理复杂、测量船现有方法难以从数据残差中自动辨识误差的难题,在给出外测数据轴系参数误差传递模型的基础上,提出了基于误差传递基函数开展匹配追踪的测量船误差溯源方法,通过误差的迭代辨识,匹配误差,定位误差,并准确估计误差值,实现测量船误差的自动识别,提高船载设备误差辨识的效率和精度。仿真分析结果证实了该方法的正确性和有效性。     

Sphk1 and Sphk2 Differentially Regulate Erythropoietin Synthesis in Mouse Renal Interstitial Fibroblast-like Cells

Erythropoietin (Epo) is a crucial hormone regulating red blood cell number and consequently the hematocrit. Epo is mainly produced in the kidney by interstitial fibroblast-like cells. Previously, we have shown that in cultures of the immortalized mouse renal fibroblast-like cell line FAIK F3-5, sphingosine 1-phosphate (S1P), by activating S1P₁ and S1P₃ receptors, can stabilize hypoxia-inducible factor (HIF)-2α and upregulate Epo mRNA and protein synthesis. In this study, we have addressed the role of intracellular iS1P derived from sphingosine kinases (Sphk) 1 and 2 on Epo synthesis in F3-5 cells and in mouse primary cultures of renal fibroblasts. We show that stable knockdown of Sphk2 in F3-5 cells increases HIF-2α protein and Epo mRNA and protein levels, while Sphk1 knockdown leads to a reduction of hypoxia-stimulated HIF-2α and Epo protein. A similar effect was obtained using primary cultures of renal fibroblasts isolated from wildtype mice, Sphk1−/−, or Sphk2−/− mice. Furthermore, selective Sphk2 inhibitors mimicked the effect of genetic Sphk2 depletion and also upregulated HIF-2α and Epo protein levels. The combined blockade of Sphk1 and Sphk2, using Sphk2−/− renal fibroblasts treated with the Sphk1 inhibitor PF543, resulted in reduced HIF-2α and Epo compared to the untreated Sphk2−/− cells. Exogenous sphingosine (Sph) enhanced HIF-2α and Epo, and this was abolished by the combined treatment with the selective S1P₁ and S1P₃ antagonists NIBR-0213 and TY52156, suggesting that Sph was taken up by cells and converted to iS1P and exported to then act in an autocrine manner through S1P₁ and S1P₃. The upregulation of HIF-2α and Epo synthesis by Sphk2 knockdown was confirmed in the human hepatoma cell line Hep3B, which is well-established to upregulate Epo production under hypoxia. In summary, these data show that sphingolipids have diverse effects on Epo synthesis. While accumulation of intracellular Sph reduces Epo synthesis, iS1P will be exported to act through S1P₁₊₃ to enhance Epo synthesis. Furthermore, these data suggest that selective inhibition of Sphk2 is an attractive new option to enhance Epo synthesis and thereby to reduce anemia development in chronic kidney disease.     

四针状氧化锌纳米材料的发射稳定性研究

采用四针状氧化锌纳米材料作为阴极发射体制作了真空场发射二极管,观察其阴极发射电流的稳定性。在实验过程中,阴极发射电流的波动幅度在2％以下,说明四针状氧化锌纳米发射体具有较好的发射稳定性。     

三聚氰胺甲醛树脂改性及其纤维的性能

三聚氰胺甲醛树脂是热固性高聚物,成纤性差,成纤纤维韧性差;通过苯代三聚氰胺、聚乙烯醇(PVA)对三聚氰胺树脂进行改性,提高了树脂溶液的可纺性,所制纤维的柔韧性得到了提高。通过红外光谱、SEM、TG-DTA研究了纤维的结构、形态及耐热性。     

合成Fe3 Si-Ti(C,N)多相材料的热力学研究

本文利用热力学分析了铁尾矿中主体元素可能发生的反应并对生成的产物进行了预测.理论分析表明,尾矿中Fe3O4和FeTiO3的还原是逐级进行的,虽有中间产物的产生,但随温度的升高,最终转化为Fe3Si和Ti(C,N),这为合成制备Fe-Si-Ti多相材料提供了理论基础.在热力学分析的基础上,采用碳热还原氮化法制备了Fe3Si-Ti(C,N)多相材料,并借助XRD和SEM对烧结体的物相和显微形貌进行了表征.结果表明,1300℃以上时,产物的主晶相为Fe3Si和Ti(C,N),与热力学分析结果吻合.通过SEM分析可知,生成的Ti(C,N)相富集在Fe3Si相的周围,形成一种高硬度、耐磨、抗腐蚀的复合材料,表明这是一条从废弃尾矿制得良好的耐磨材料的绿色工艺.     

Indikatorenbasierte Evaluierung von Fischhabitaten in alpinen Fließgewässern

The EU Water Framework Directive commits member states to achieve good ecological status in all waterbodies. Artificial or heavily modified waterbodies must reach at least its good ecological potential. In view of these requirements, simple and feasible methods are required in order to evaluate habitat suitability for relevant target species in larger river reaches. Well-developed models for determining the relationship between stream flows and habitat for target species mainly based on micro- and meso-scale already exist. However, the application of such models is complex and time-consuming and consequently limited to relatively short river segments. The objective of this study is to develop a simplified applicable assessment model to evaluate habitat conditions for selected target fish. This model uses hydro-morphological indicators for the habitat assessment and relies on correlative relations between habitat suitability and hydro-morphological features of river stretches (average Froude-number, relative flow width, mean bed slope, relative water depth and flow velocity). The indicators were determined as reach-related averages, derived from 2D model simulations (hydraulic and habitat-specific). Particular emphasis was laid on using a wide range of river stretches with different hydro-morphological characteristics (hydrology, bed substratum, bed structures, degree of braiding, sinuosity of the river course, mean bed width and bed slope). As a result, a set of model equations enables the evaluation of fish habitat conditions in river stretches as a function of flow and morphology. The habitat suitability assessment focuses on four preselected target species: brown trout, European grayling and for low slope rivers common nase and barbel.     

生物聚合物调剖技术

以老区高含水油田为目标，开展生物聚合物调剖技术研究。在生物聚合物特性研究的基础上，探讨了岩心注入能力和封堵调剖能力。在取得室内物模驱油试验提高采收率9％，油井堵水增油647t后，对2口水井进行了生物聚合物调剖矿场试验，周围油井含水率下降7．7％～64．5％，一年来持续有效。通过矿场试验的跟踪监测和动态分析，明确了影响生物聚合物调剖效果的主要环节及因素，为该项技术的深入研究和大规模推广应用指明了方向。     

HRV系列降粘剂在冀中南部稠油开采中的应用

为解决冀中南部１０多个稠油油藏原油粘度高,开采难度大的问题,开发了应用ＨＲＶ系列乳化降粘剂开采此类油藏的新方法,解决了稠油在地层,井筒难以流动的问题,而且使稠油的地面输送简单化现场应用表明,ＨＲＶ系列稠油乳化降粘剂使用浓度小,乳化效率高,降粘效果好,同时不影响原油破乳,具有较大的推广使用价值。     

基于IEC 61850的电力设备远程控制方法

远程控制已成为确保电力系统安全稳定运行的重要技术手段,IEC 61850对电力设备的远程控制提出了更高的要求。以增强安全的操作前选择控制的有限状态机为基础,提出了基于IEC 61850的电力远动系统的远程控制模型。结合实际应用的需要,设计了基于IEC 61850的远方控制接口,实现了对智能电子设备（IED）的远程访问控制,对断路器进行了断开与闭合操作。基于上述研究所开发的系统通过了在某地区电网进行的工业现场试验并试运行,验证了模型的正确性和方案的可行性。     

近地大气532 nm激光散射的实验与计算

通过实验测出532 nm激光在近地大气的角散射系数,对Junge和Deirmendjian两种模型的气溶胶系统在不同的系统参数、不同的折射率的情况下的散射相函数进行了计算,发现与实验所测得的曲线有明显的差异,这两种模型都不存在散射次极峰.通过对不同半径粒子的散射相函数的计算,说明实验所测的气溶胶系统在粒子尺寸较大的区间的密度要比Junge和Deirmendjian两种模型的密度要大得多,在假定大粒子服从正态分布的前提下,拟合出了气溶胶的分布函数.