Rapid assembly of polyelectrolyte multilayer membranes using an automatic spray system

The layer‐by‐layer (LbL) assembly of polyelectrolyte multilayers on to a porous supporting membrane is able to create various new composite membranes. However, the low efficiency and long time required for such procedures limit practical applications. In this study, an automatic spray system has been constructed for the rapid assembly of polyelectrolyte multilayers on to nanoporous supporting membranes. The compounds polyacrylic acid and poly(ethyleneimine), used as a model polyelectrolyte pair, were alternately sprayed on to a polyacrylonitrile ultrafiltration membrane. Experiments proved that the composite membrane obtained in this way had a good pervaporation dehydration performance. In addition, the process times were dramatically decreased, by as much as 80 folds, when compared with classical dip‐LbL methods. Such an automated system can easily be converted to the assembly of various organic species. Therefore, it is a versatile and highly efficient system for manufacturing composite multilayer membranes for many separation applications. © 2012 American Institute of Chemical Engineers AIChE J, 59: 250–257, 2013     

Role of Akirin in Skeletal Myogenesis

Akirin is a recently discovered nuclear factor that plays an important role in innate immune responses. Beyond its role in innate immune responses, Akirin has recently been shown to play an important role in skeletal myogenesis. In this article, we will briefly review the structure and tissue distribution of Akirin and discuss recent advances in our understanding of its role and signal pathway in skeletal myogenesis.     

制药废水处理工程实例

根据制药废水的组成和特点,采用IC厌氧反应器-A/A/O-二级A/O-芬顿高级氧化-曝气生物滤池为主体的处理工艺,目前出水水质稳定达到《污水综合排放标准》GB8978-1996中的一级标准,系统运行稳定,可为同类型工业污水的处理提供参考经验.     

双十六氟壬醇琥珀酸单酯胺盐在硝基复合肥防结块中的应用

以含十六氟壬醇的副产物和琥珀酸酐为原料合成十六氟壬醇琥珀酸单酯,再用二乙烯三胺中和十六氟壬醇琥珀酸单酯,即可得到双十六氟壬醇琥珀酸单酯胺盐。确定了双十六氟壬醇琥珀酸单酯胺盐在硝基复合肥防结块剂中的添加量为6％（质量分数）时,可替代原配方中的伯胺盐和仲胺盐,并能明显提高防结块剂的防结块效果。     

以科研项目为导向优化材料类实验室

当今高校教育教学过程中,越来越需要将理论教学和科研项目融合在一起,通过二者的相互作用,增强学生实验教学的学习效果.科研项目制度化和科学化的管理,既能够保证科研项目圆满完成,又能为实验教学的实施提供一定的环境和实施内容,确保高校教育及实验教学能够最大化地出成果、出人才.本文探讨了材料类科研项目和教学实验相互融合的方法,并提出了适合将材料类科研项目转化成学生实验教学的建议.     

全日制工程硕士创新型实践教学的探索

围绕为制药领域培养基础扎实、素质全面、工程实践能力强并具有一定创新能力的应用型、复合型高层次工程技术和工程管理人才的培养目标,我们在课程设置、实践教学环节等方面研究和探索全日制工程硕士专业学位研究生教育培养模式,以适应国家研究生培养类型和模式改革。     

Fabrication of Three-Dimensionally Ordered Macroporous TiO2 Films with Enhanced Photovoltaic Conversion Efficiency

Negative-charged polystyrene (PS) microspheres were prepared through a soap-free emulsion polymerization method using potassium persulfate as initiator. Three-dimensionally ordered macroporous TiO₂ films were fabricated using the high-quality PS colloidal crystals templates obtained via a horizontal deposition method. The as-prepared macroporous TiO₂ films were applied as the photoanodes in dye-sensitized solar cell (DSSC). The microstructure of the products were characterized by X-ray diffractometer, fourier transform infrared spectroscopy, scanning electron microscopy, transmission electron microscopy and nitrogen adsorption–desorption analyzer. The results showed that the macroporous TiO₂ films replicated well the 3D ordered structure derived from PS colloidal crystal templates and revealed a relatively large specific surface area (69.99 m²/g), which could increase the capacity of TiO₂ film anode for absorbing dyes and scattering light. The photocurrent–voltage (I–V) characteristics of DSSC were measured by a digital source meter under simulated solar light. The results indicated that the introduction of an ordered macroporous TiO₂ interfacial layer increased the photovoltaic conversion efficiency, which was improved by 68 % from 3.61 to 6.08 %, as compared to a device using a bare P25 TiO₂ photoanode. Our results showed that the hierarchically ordered macroporous TiO₂ bilayer films photoanode for DSSC could be helpful to improve the photovoltaic conversion efficiency.     

聚合双酸铝铁絮凝剂对APMP制浆废水处理效果的研究

以生产钛白粉的废弃物和铝矾土熟料为主要原料,合成了聚合双酸铝铁(PAFCS)絮凝剂,并将PAFCS用于APMP制浆废水的混凝处理,以正交试验分析,确定了优化的混凝条件。结果表明,在优化混凝条件下,水样COD和色度的去除率高达97.4%和97.5%。与PFS和PAC相比,PAFCS混凝处理效果最好,且成本低廉。     

Paclitaxel-loaded nanoparticles of star-shaped cholic acid-core PLA-TPGS copolymer for breast cancer treatment

A system of novel nanoparticles of star-shaped cholic acid-core polylactide-d-α-tocopheryl polyethylene glycol 1000 succinate (CA-PLA-TPGS) block copolymer was developed for paclitaxel delivery for breast cancer treatment, which demonstrated superior in vitro and in vivo performance in comparison with paclitaxel-loaded poly(d,l-lactide-co-glycolide) (PLGA) nanoparticles and linear PLA-TPGS nanoparticles. The paclitaxel- or couramin 6-loaded nanoparticles were fabricated by a modified nanoprecipitation method and then characterized in terms of size, surface charge, surface morphology, drug encapsulation efficiency, and in vitro drug release. The CA-PLA-TPGS nanoparticles were found to be spherical in shape with an average size of around 120 nm. The nanoparticles were found to be stable, showing no change in the particle size and surface charge during 90-day storage of the aqueous solution. The release profiles of the paclitaxel-loaded nanoparticles exhibited typically biphasic release patterns. The results also showed that the CA-PLA-TPGS nanoparticles have higher antitumor efficacy than the PLA-TPGS nanoparticles and PLGA nanoparticles in vitro and in vivo. In conclusion, such nanoparticles of star-shaped cholic acid-core PLA-TPGS block copolymer could be considered as a potentially promising and effective strategy for breast cancer treatment.