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首先．本人声明,此篇小文并非与本版责编LSKEI叫嚣。但是,对于Lskei所提出的“信息过载”,本人确实持有不同意见。     

A scalable kernel-based semisupervised metric learning algorithm with out-of-sample generalization ability

In recent years, metric learning in the semisupervised setting has aroused a lot of research interest. One type of semisupervised metric learning utilizes supervisory information in the form of pairwise similarity or dissimilarity constraints. However, most methods proposed so far are either limited to linear metric learning or unable to scale well with the data set size. In this letter, we propose a nonlinear metric learning method based on the kernel approach. By applying low-rank approximation to the kernel matrix, our method can handle significantly larger data sets. Moreover, our low-rank approximation scheme can naturally lead to out-of-sample generalization. Experiments performed on both artificial and real-world data show very promising results.     

仗剑江湖网游路，降妖除魔唯剑仙——《剑仙》体验手记

千秋北斗,瑶富寒苦,不若做回潇洒剑仙,笑傲百年人世江湖。《剑仙》作为搜狐首款仙侠网游,游戏中怪物与人物设计风格上也走的是纯粹的“中国风”路线,东方神话中涉及的奇幻鬼怪等造型在游戏中被刻画的极为生动。其实提到剑仙,我们并不陌生,而且这一称谓由来已久,历来民间各种修真道书汗牛充栋,但对剑仙一脉总是避而不谈或一笔带过,所谓理可明宣,术宜秘传也。正史《宋史·陈抟传》云：“关西逸人吕洞宾有剑术,百余岁而童颜,步厦轻疾,顷刻数百里,世以为神仙,皆数来陈斋中,人咸异之。”     

电弧闪光

电弧闪光与触电相比有很大的不同。当一个人触电的时候,电流会在人体的敏感组织（主要是神经）间通过,从而产生影响。电弧闪光通常在空气导电时产生,其的主要成因是两个接触的导体再次分离时将电流拉出。当电弧产生时,形成的缺口内充满了电离子,其数量迅速上升,尤其是在高压／低阻的供电情况下,例如电力输送线,这种情况更加明显。任何大于50V的电路都有可能产生电弧闪光。     

A new bioreactor for the controlled application of complex mechanical stimuli for cartilage tissue engineering

Mechanical stimuli have been shown to enhance chondrogenesis on both animal and human chondrocytes cultured in vitro. Different mechanical stimuli act simultaneously in vivo in cartilage tissue and their effects have been extensively studied in vitro, although often in a separated manner. A new bioreactor is described where different mechanical stimuli, i.e. shear stress and hydrostatic pressure, can be combined in different ways to study the mechanobiology of tissue engineered cartilage. Shear stress is imposed on cells by forcing the culture medium through the scaffolds, whereas a high hydrostatic pressure up to 15 MPa is generated by pressurizing the culture medium. Fluid-dynamic experimental tests have been performed and successful validation of the bioreactor has been carried out by dynamic culture of tissue-engineered cartilage constructs. The bioreactor system allows the investigation of the combined effects of different mechanical stimuli on the development of engineered cartilage, as well as other possible three-dimensional tissue-engineered constructs.     

驾驭电力

控制工程师也许会天真地认为,设备管理者会像变魔术般为他们搭建好的自动化系统提供数量充足、质量上乘的电能。但事实是,这些自动化系统很可能会打乱电力分配体系的平衡状态,并降低供电质量。同时,控制工程师时常会过分追求供电质量,从而心生报怨。     

为什么显示器也需要通过Vista认证

最近有些读者朋友问：现在微软为什么这么霸道,连显示器都要通过它的认证,没有通过Windows Vista认证的液晶显示器会有什么不同吗？液晶显示器和Windows Vista操作系统之间到底有什么必要的联系呢？通过Windows Vista认证的显示器又有什么好处呢？针对上述种种疑问,今天我们将为大家一一解答。     

Contribution of h-bonding to the preference of platinum anti-tumour drugs for particular bases and particular cross-links

The stereochemical factors that influence the tendencies for sequence specific binding of platinum antitumour drugs to DNA are examined. The NHs of the platinum-amine moiety can form hydrogen bonds to the O6 of guanine or to a phosphate oxygen of DNA. Modelling the stereochemistry of the NH atoms can lead to compounds with a strong preference for forming one type of adduct with DNA.