Determination of precompression and compression force levels to minimize tablet friability using simplex

Pilot simplex experiments for improving the tablet strength of three aspirin tablet formulations based on precompression and compression forces were presented. As each simplex moved towards the direction of the optimum, the friability was being minimized and the crushing strength was concomittantly being maximized. Because it followed a systematic direction, simplex process would locate a local optimum rapidly. The appropriate levels of precompression and compression forces that produced tablets with the desired strength were attained in five trials. By contrast, random search for this force combination required at least ten trials. Simplex technique is a cost and time effective means for determining the precompression and compression forces that will reduce the friability or increase the hardness of a tablet formulation. Results appeared to also indicate that crushing strength might be a more reliable measure of tablet strength than friability.     

Criteria for evaluation of the hardening factor of machine parts

V. Ya. Chubar' Zaporozhe Machine Building Institute. Translated from Problemy Prochnosti, No. 3, pp. 62–65, March, 1989.     

Strength of small-scale spherical shells formed from pressed glass elements

Institute of Strength Problems, Academy of Sciences of the Ukrainian SSR, Kiev. Sumy Branch, Khar'kov Polytechnic Institute. Translated from Problemy Prochnosti, No. 8, pp. 102–104, August, 1989.     

Dynamic viscosities of mixtures of n-butyraldehyde and isobutyraldehyde over wide ranges in the state parameters

Dynamic-viscosity measurements are reported for liquid mixtures in the system formed by n-butyraldehyde and isobutyraldehyde.Translated from Inzhenerno-Fizicheskii Zhurnal, Vol. 48, No. 2, pp. 321–322, February, 1985.     

Modelling induction skull melting design modifications

Induction Skull Melting (ISM) is used for heating, melting, mixing and, possibly, evaporating reactive liquid metals at high temperatures when a minimum contact at solid walls is required. The numerical model presented here involves the complete time dependent process analysis based on the coupled electromagnetic, temperature and turbulent velocity fields during the melting and liquid shape changes. The simulation is validated against measurements of liquid metal height, temperature and heat losses in a commercial size ISM furnace. The often observed limiting temperature plateau for ever increasing electrical power input is explained by the turbulent convective heat losses. Various methods to increase the superheat within the liquid melt, the process energy efficiency and stability are proposed.     

A personal computer based system used in electromyography for interpretation and reporting

Programs for rule based electromyography (EMG) interpretation and reporting are described. A number of parameters are obtained during an EMG investigation. The combination of these data leads to a neurophysiological conclusion. Knowledge from the literature, research and experience is the basis for rule development. Rules have been developed for 14 of the most commonly used classifications of an EMG. The syntax is relatively easy and the user may change the rules, add rules or apply the system for other types of data. The results are displayed in a new graphical way. The system presented here is part of an integrated EMG laboratory with administrative routines, distributed databases for storage of results and routines for automatic report generation.     

High-gain pseudomorphic InGaAs base ballistic hot-electron device

A high-gain ballistic hot-electron device is described. The GaAs-AlGaAs heterostructure device, with a 21-mm-thick pseudomorphic In _0.12Ga_0.88As base, had a current gain of 27 at 77 K and 41 at 4.2 K. As characteristically seen in ballistic devices, transfer into the L valley limited the maximum gain. The Γ-L valley separation in the strained In_0.12Ga_0.88As was estimated to be about 380 meV     

Phase relations in the ternary system Cu-In-Se

The phase relations of the ternary system Cu-In-Se were studied at 750° C by quenching experiments. Special attention was given to the region CuInSe₂In₂Se₃-In₄Se₃. Only four ternary phases with extended homogeneity ranges were found to exist. They were characterized by X-ray powder diffraction, electron microprobe analysis (EK8PA)' end optical microscopy. Differential thermal analysis (DTA) investigations allowed us to construct theT-x diagram of the Cu₂Se-In₂Se₃. out between 47 and 100 mol% In₂Se₃. Besides, it was also possible to give a tentative diagram of the solid-liquid equilibria at 750° C and to get some information on the sub-solid existence fields beside the Cu₂Se-In₂Se₃ cut.