川东南涪陵地区五峰—龙马溪组硅质页岩的生物成因及其油气地质意义

为研究川东南地区五峰—龙马溪组富有机质硅质页岩的成因,选取川东南涪陵页岩气探区钻井岩心样品,采用X射线衍射（XRD）、光学显微镜、环境扫描电子显微镜和能谱仪开展了岩石的矿物组成、微观形貌和成分与结构特征研究。五峰组和龙马溪组下段页岩的矿物组成以石英为主,向上至龙马溪组中部和上部石英含量逐渐降低,黏土矿物含量明显增加。镜下观察到大量具清晰圈层状生长结构和针状结构的生物残体和碎屑,特别是在五峰组和龙马溪组下段尤为丰富,外观具有放射虫和海绵骨针的典型形貌特征。前者内部具有明显的圈层和外部裙边状结构,碎屑骨架与内部充填物质均为微晶石英;碎屑间更小粒级的石英颗粒则多呈不规则球状或椭球状,自形程度低,充填在矿物基质中,应属生物硅质溶解再沉淀形成的自生石英。后者则以较完整和碎屑两种形式呈分散状分布在矿物基质中。五峰—龙马溪组高丰度硅质生物及其硅质重结晶产物的存在,为该段硅质页岩的生物成因提供了直接证据,具有古生产力恢复、水体沉积环境追溯、微观孔隙结构和岩石力学分析等多方面重要的油气地质意义。     

Critical Roles of Circular RNA in Tumor Metastasis via Acting as a Sponge of miRNA/isomiR

Circular RNAs (circRNAs), a class of new endogenous non-coding RNAs (ncRNAs), are closely related to the carcinogenic process and play a critical role in tumor metastasis. CircRNAs can lay the foundation for tumor metastasis via promoting tumor angiogenesis, make tumor cells gain the ability of migration and invasion by regulating epithelial-mesenchymal transition (EMT), interact with immune cells, cytokines, chemokines, and other non-cellular components in the tumor microenvironment, damage the normal immune function or escape the immunosuppressive network, and further promote cell survival and metastasis. Herein, based on the characteristics and biological functions of circRNA, we elaborated on the effect of circRNA via circRNA-associated competing endogenous RNA (ceRNA) network by acting as miRNA/isomiR sponges on tumor angiogenesis, cancer cell migration and invasion, and interaction with the tumor microenvironment (TME), then explored the potential interactions across different RNAs, and finally discussed the potential clinical value and application as a promising biomarker. These results provide a theoretical basis for the further application of metastasis-related circRNAs in cancer treatment. In summary, we briefly summarize the diverse roles of a circRNA-associated ceRNA network in cancer metastasis and the potential clinical application, especially the interaction of circRNA and miRNA/isomiR, which may complicate the RNA regulatory network and which will contribute to a novel insight into circRNA in the future.     

改进的混凝土重力拱坝温度荷载分析

针对目前拱坝规范中温度荷载不能较好地考虑重力拱坝内部温度的非线性变化,由外界气温变化对混凝土内部温度影响的理论分析及坝体温度计测值的综合分析,对年变化温度荷载的计算进行了改进：仅对外界气温变化影响较显著的距坝体外表面10 m左右区域的混凝土温度进行等效,假设中间区域的温度无变化。这可一定程度考虑坝体内部温度的非线性变化。对某重力拱坝进行分析,得到的结论是：①采用本文提出的考虑坝内温度非线性变化的温度荷载方法计算的应力较规范计算的应力,在下游面拉应力有较大增长,而上游面压应力有所减小;②计算坝体的变形与规范法计算的变形较接近,但截面上的应力分布不同。     

Creation and control of high-dimensional multi-partite classically entangled light

Vector beams, non-separable in spatial mode and polarisation, have emerged as enabling tools in many diverse applications, from communication to imaging. This a...     

哈拉沁水库泄洪洞进水塔静动力分析

利用4—21节点块体单元对哈拉沁水库泄洪洞进水塔进行离散,分析6种工况下进水塔结构的自振特性,并通过反映谱法计算顺水向和垂直水向结构的抗震动力响应,包括结构的动位移和动应力。将动力计算结果与静力计算结果进行叠加,成果显示进水塔的变形和强度均满足要求,为工程设计提供了依据。     

双色注射成形技术及模具设计

双色注射成形可满足产品结构、性能、外观的特殊要求,而逐渐被广泛应用.该文就双色注射成形原理、技术和应用作简单描述,并简要介绍双色注射模具的结构特点及其设计要点.     

基于奇异值分解技术的离心机故障诊断

在简单介绍WH-800型离心机基本结构及工作原理的基础上,介绍了基于重构吸引子轨迹矩阵的奇异值分解技术,并引入自相关函数对现有奇异值分解技术加以改进．通过对现场实测故障信号的分析,表明改进的奇异值分解技术具有很好的降噪效果,能在强噪声背景环境下准确提取设备的故障特征信号,为离心机的故障诊断提供了一种新的思路．     

通用网络辅助教学支撑平台的研制

开展网络辅助教学,需要建设一个功能强大使用方便的支撑平台.本文摈弃了一般的教学网站思维,把各个专业的各门课程集中在一个系统中,大大降低了网络辅助教学的门槛和维护难度,使教师从课程网站的建设与维护的琐事中解脱出来,专心于课程本身内容的研究和更新,学生可在一个系统中完成所有课程的学习,缩短了课程转换时网络浏览所需的时间.     

Sensing mechanism of Ag/α-MoO3 nanobelts for H2S gas sensor

Sensing mechanism is still a big problem in the field of gas sensor.In-depth study of the sensing mecha-nism can provide better ideas for the design of sensing ...     

大采高仰采面煤壁片帮机理及加固技术研究

针对经坊煤业3-602大采高仰采工作面煤壁片帮问题,分析了煤壁片帮机理,确定片帮形式为拉裂破坏和剪切破坏;分析了采高和仰采角度对工作面顶板结构的影响,并确定了两巷超前注浆、工作面煤壁注浆两种不同加固方案及其具体技术参数,大大提高了煤壁及顶板稳定性,保证了工作面的安全开采.