Technical and Economic Advantages of Producing and Applying Ozone At High Concentration

Today ozone can be produced in concentrations up to 3.5 wtJ (12 g/Nm³) in air and 7 wt% (92 g/Nm³) in oxygen with simultaneously low specific energy consumption. The high concentrations improve the transfer efficiency and the reaction kinetics of ozone. This is demonstrated with reference to the design basis of the water treatment plants of Los Angeles, Dordrecht and Jeddah. In all cases the overall costs per kilogram of ozone are minimized by choosing the appropriate ozone concentration between 2 wt% (24 g/Nm³) and 6 wt% (79 g/Nm³).     

Dynamics and circuit of a chaotic system with a curve of equilibrium points

Although chaotic systems have been intensively studied since the 1960s, new systems with mysterious features are still of interest. A novel chaotic system including hyperbolic functions is proposed in this work. Especially, the system has an infinite number of equilibrium points. Dynamics of the system are investigated by using non-linear tools such as phase portrait, bifurcation diagram, and Lyapunov exponent. It is interesting that the system can display coexisting chaotic attractors. An electronic circuit for realising the chaotic system has been implemented. Experimental results show a good agreement with theoretical ones.     

A Matrix Decomposition MFS Algorithm for Biharmonic Problems in Annular Domains

The Method of Fundamental Solutions (MFS) is a boundary-type method for the solution of certain elliptic boundary value problems. In this work, we develop an efficient matrix decomposition MFS algorithm for the solution of biharmonic problems in annular domains. The circulant structure of the matrices involved in the MFS discretization is exploited by using Fast Fourier Transforms. The algorithm is tested numerically on several examples.     

Linearisation via input–output injection of time delay systems

This paper deals with the problem of linearisation of systems with constant commensurable delays by input–output injection using algebraic control tools based on the theory of non-commutative rings. Solutions for the problem of linearisation free of delays, and with delays of an observable nonlinear time-delay systems are presented based on the analysis of the input–output equation. These results are achieved by means of constructive algorithms that use the nth derivative of the output expressed in terms of the state-space variables instead of the explicit computation of the input–output representation of the system. Necessary and sufficient conditions are established in both cases by means of an invertible change of coordinates.     

The Antecedents of Individual Innovative Behaviour in Temporary Group Innovation

This study examines the antecedents of individual innovative behaviour in short‐term innovation camp conditions. Innovation is increasingly a joint activity conducted in various kinds of temporary settings that collect widely diverse people together for a brief time to work on a particular problem. As innovativeness of interplaying individuals is key for the success of collaborative innovation, it is important to study what factors enhance individual innovative behaviour in temporary settings. Data from 103 innovation camp participants were the basis of PLS‐SEM analysis. Results show that individual creative self‐efficacy, perceived task orientation and experimentation have significant effects on individual innovative behaviour. In contrast, participative safety, support for innovation, and vision are not associated with individual innovativeness. These findings suggest that the antecedents of individual innovativeness in temporary settings differ from those identified in conventional groups, pointing to a new field for future research.     

The discovery of compounds that stimulate the activity of kallikrein-related peptidase 3 (KLK3)

Kallikrein-related peptidase 3 (KLK3), also known as prostate-specific antigen (PSA), is the most useful biomarker for prostate cancer (PCa). KLK3 is suggested to play a role in regulating cancer growth through anti-angiogenic activity in vivo and in vitro. This feature, together with its specificity for prostate tissue, makes KLK3 an intriguing target for the design of new therapies for PCa. 3D pharmacophores for KLK3-stimulating compounds were generated based on peptides that bind specifically to KLK3 and increase its enzymatic activity. As a result of pharmacophore-based virtual screening, four small, drug-like compounds with affinity for KLK3 were discovered and validated by capillary differential scanning calorimetry. One of the compounds also stimulated the activity of KLK3, and is therefore the first published small molecule with such an activity.