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71.
In this study, the effect of etchant type and etching conditions on the root and airfoil microstructure of a service-exposed IN738 turbine blade has been investigated. The microstructure of superalloy components used at high temperatures, in addition to the usual microstructural changes, experiences deterioration in micrometer dimensions. In order to investigate these changes, electrochemical etching was performed on the samples with the chemical solution including 80% phosphoric acid, solution containing Cr2O3 and 55% glycerol. Chemical etching was performed with marble and etchant solution containing 60% glycerol. The results in terms of specifying the deterioration effects on microstructure of the blade applied at high temperature, the amount of γ′ phase and the best etchant were investigated. Among the solutions used for chemical etching, the solution containing 10 ml HNO3, 50 ml HCl and 60 ml glycerol was appropriate for detection of segregations and dendrites, and among the electrochemical etching solutions, the Cr2O3 solution was found suitable for specifying γ′ precipitates’ morphology by scanning electron microscopy. In this research, the results of the quantitative analysis of the images provided by these etchants were also investigated.  相似文献   
72.
A reinforced double network (DN) hydrogel as a candidate for skin scaffold was prepared. It consists of O-carboxymethyl chitosan, polyvinyl alcohol, honey, CaCl2, and graphene oxide. The various concentrations of CaCl2, namely, 30, 45, and 60 wt% were investigated. Besides, the GO content was studied as 3, 5, and 10 wt%. The structure of the DN was characterized by Fourier-transform infrared spectroscopy, thermogravimetric analysis, differential scanning calorimetry, X-ray diffraction, energy dispersive X-ray and Brunauer-Emmett-Teller were evaluated. The mechanical properties were studied, too. It showed that the DN with 45 wt% CaCl2 was optimized. Also, swelling mechanism was investigated. Moreover, with the increase in GO content, the mechanical strength was increased. The cytotoxicity was evaluated and it was indicated that DN with 45% CaCl2 and 5% GO had an acceptable level of biocompatibility. Moreover, scanning electron microscopy images showed the porous structure of the DN nanocomposite. Thus, the DN has the potential to be applied in tissue engineering as a skin scaffold. POLYM. ENG. SCI., 60:889–899, 2020. © 2020 Society of Plastics Engineers  相似文献   
73.
Engineering with Computers - Blast-induced ground vibration is considered as one of the most hazardous phenomena of mine blasting, which can even cause casualties and severe damages to the adjacent...  相似文献   
74.
To explore the effect of combination therapy of epirubicin (Epi) and melittin (Mel) to cancer cells, calcium carbonate nanoparticles (CCN), as carriers, were developed which were modified with MUC1-Dimer aptamers as targeting agents. Both Epi and Mel were delivered at the same time to cancer cells overexpressing the target of MUC1 aptamer, mucin 1 glycoproteins (MCF7 and C26 cells). CCN were prepared with a water-in-oil emulsion method. Epi and Mel were separately encapsulated in CCN and the nanoparticles were modified with MUC1-Dimer aptamers. In vitro studies, including MTT assay, flow cytometry analysis and fluorescence imaging were applied to investigate the targeting and cell proliferation inhibition capabilities of MUC1-Dimer aptamer-CCN-Mel complex and MUC1-Dimer aptamer-CCN-Epi complex in the target (MCF-7 and C26 cells) and nontarget (HepG2) cells. Also, the function of the developed complexes was analyzed using in vivo tumor growth inhibition. The release of Epi from MUC1-Dimer aptamer-CCN-Epi complex was pH-sensitive. Cellular uptake studies showed more internalization of the MUC1-Dimer aptamer-CCN-Epi complex into MCF-7 and C26 cells (target) compared to HepG2 cells (nontarget). Interestingly, the MUC1-Dimer aptamer-CCN-Mel complex and MUC1-Dimer aptamer-CCN-Epi complex indicated very low toxicity as compared to target cells. Moreover, co-delivery of Epi and Mel using the mixture of MUC1-Dimer aptamer-CCN-Mel complex and MUC1-Dimer aptamer-CCN-Epi complex exhibited strong synergistic cytotoxicity in MCF-7 and C26 cells. Furthermore, the presented complexes had a better function to control tumor growth in vivo compared to free Epi.  相似文献   
75.
The optimum design of structures under static loads is well-known in the design world; however, structural optimization under dynamic loading faces many challenges in real applications. Issues such as the time-dependent behavior of constraints, changing the design space in the time domain, and the cost of sensitivities could be mentioned. Therefore, optimum design under dynamic loadings is a challenging task. In order to perform efficient structural shape optimization under earthquake loadings, the finite element-based approximation method for the transformation of earthquake loading into the equivalent static loads (ESLs) is proposed. The loads calculated using this method are more accurate and reliable than those obtained using the building regulations. The shape optimization of the structures is then carried out using the obtained ESLs. The proposed methodologies are transformed into user-friendly computer code, and their capabilities are demonstrated using numerical examples.  相似文献   
76.
Wireless body sensor networks are offered to meet the requirements of a diverse set of applications such as health‐related and well‐being applications. For instance, they are deployed to measure, fetch and collect human body vital signs. Such information could be further used for diagnosis and monitoring of medical conditions. IEEE 802.15.4 is arguably considered as a well‐designed standard protocol to address the need for low‐rate, low‐power and low‐cost wireless body sensor networks. Apart from the vast deployment of this technology, there are still some challenges and issues related to the performance of the medium access control (MAC) protocol of this standard that are required to be addressed. This paper comprises two main parts. In the first part, the survey has provided a thorough assessment of IEEE 802.15.4 MAC protocol performance where its functionality is evaluated considering a range of effective system parameters, that is, some of the MAC and application parameters and the impact of mutual interference. The second part of this paper is about conducting a simulation study to determine the influence of varying values of the system parameters on IEEE 802.15.4 performance gains. More specifically, we explore the dependability level of IEEE 802.5.4 performance gains on a candidate set of system parameters. Finally, this paper highlights the tangible needs to conduct more investigations on particular aspect(s) of IEEE 802.15.4 MAC protocol. Copyright © 2015 John Wiley & Sons, Ltd.  相似文献   
77.
In this study, a numerical modeling approach was used to investigate the current-voltage behavior of conductive nanoplatelet-based nanocomposites. A three-dimensional continuum Monte Carlo model was employed to randomly disperse the nanoplatelets in a cubic representative volume element. A nonlinear finite element-based model was developed to evaluate the electrical behavior of the nanocomposite for different levels of the applied electric field. Also, the effect of filler loading on nonlinear conductivity behavior of nanocomposites was investigated. The validity of the developed model was verified through qualitative comparison of the simulation results with results obtained from experimental works.  相似文献   
78.
A new wetting mechanism, termed electro-elastic wetting, and methods to exploit it for droplet manipulation are proposed and demonstrated. The system consists of a droplet of dielectric liquid, an elastic and conductive membrane as its shell, and an electrode-dielectric composite as its substrate. Activation is by an electric field applied between the membrane and the substrate. The equilibrium shape of the droplet is determined by the balance of membrane tension and electrostatic attraction. It is shown that the contact angle of the droplet is governed by a modified Young–Lipmann Equation. It is then demonstrated that it is possible to transport the droplet along a controlled direction, as well as to actively tune its shape, topography, and position by manipulating the spatial distribution of the electrical force.  相似文献   
79.
Multimedia Tools and Applications - An end-to-end text-to-speech system generates acoustic features directly from input text to synthesize speech from it. The challenges of using these models for...  相似文献   
80.
Multimedia Tools and Applications - Training supervised machine learning models like deep learning requires high-quality labelled datasets that contain enough samples from various categories and...  相似文献   
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