Hexabromocyclododecanes (HBCDs) in the environment and humans: a review

Hexabromocyclododecanes (HBCDs) are brominated aliphatic cyclic hydrocarbons used as flame retardants in thermal insulation building materials, upholstery textiles, and electronics. As a result of their widespread use and their physical and chemical properties, HBCDs are now ubiquitous contaminants in the environment and humans. This review summarizes HBCD concentrations in several environmental compartments and analyzes these data in terms of point sources versus diffuse sources, biomagnification potential, stereoisomer profiles, time trends, and global distribution. Generally, higher concentrations were measured in samples (air, sediment, and fish) collected near point sources (plants producing or processing HBCDs), while lower concentrations were recorded in samples from locations with no obvious sources of HBCDs. High concentrations were measured in top predators, such as marine mammals and birds of prey (up to 9600 and 19 200 ng/g lipid weight, respectively), suggesting a biomagnification potential for HBCDs. Relatively low HBCD concentrations were reported in the few human studies conducted to date (median values varied between 0.35 and 1.1 ng/g lipid weight). HBCD levels in biota are increasing slowly and seem to reflect the local market demand. One important observation is the shiftfrom the high percentage of the gamma-HBCD stereoisomer in the technical products to a dominance of the alpha-HBCD stereoisomer in biological samples. A combination of factors such as variations in solubility, partitioning behavior, uptake, and, possibly, selective metabolism of individual isomers may explain the observed changes in stereoisomer patterns. Recommendations for further work include research on how HBCDs are transferred from products into the environment upon production, use, and disposal. Time trends need to be analyzed more in detail, including HBCD stereoisomers, and more data on terrestrial organisms are needed, especially for humans. Whenever possible, HBCDs should be analyzed as individual stereoisomers in order to address their fate and effects.     

Using technology to explore social networks and mechanisms underlying peer effects in classrooms.

Peer interactions among children have long interested social scientists. Identifying causal peer effects is difficult, and a number of studies have used random assignment to produce evidence that peers affect each other's outcomes. This focus by sociologists and economists on whether peers affect each other has not been matched by direct evidence on how these effects operate. The authors argue that one reason for the small number of studies in sociology and economics on the mechanisms underlying peer effects is the difficulty of collecting data on microinteractions. They argue technology reduces data collection costs relative to direct observation and allows for realistic school activities with randomly assigned peers. The authors describe a novel strategy for collecting data on peer interactions and discuss how this approach might shed light on mechanisms underlying peer influence. The centerpiece of this strategy is the use of handheld computers by middle and high school students as part of interactive math and science lessons called the Discussion Game. The handhelds collect data on interactions between students and track how students' answers evolve as they interact with different peers. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Thermopower of YBa2Cu3O7-δ–Ag Composites

The percolation behavior of normal-state thermopower, resistivity, and superconductivity have been studied in YBa₂Cu₃O_7-δ─Ag (YBCO─Ag) composite systems. The normal-state resistivity and thermopower show a percolation threshold at a Ag volume fraction ( V _Ag) of 20% to 30%, whereas the superconducting network shows a threshold at a V _Ag of ≅70% to 80%. The results obtained from this study show that the YBCO─Ag composite obtained from Ag₂O and YBCO powders is uniformly distributed with Ag and YBCO remaining as separate phases without changing their characteristics. The measurements of thermopower indicate that the normal-state thermopower and phonon-drag thermopower are affected by the Ag addition. The stability of YBCO is increased when it is in composite form.     

发酵麦麸及其面包面团中阿拉伯木聚糖溶解性与酚酸释放研究

将发酵麦麸作为功能配料用于高膳食纤维面包面团制作,采用化学分析、高效液相色谱及离子色谱法分析麦麸发酵、面包制作过程及面包中阿拉伯木聚糖溶解性和酚类化合物释放。结果表明：随着发酵时间延长,麦麸中水溶性阿拉伯木聚糖、游离酚及阿魏酸含量逐渐增加。发酵处理后,麦麸中游离阿拉伯糖、葡萄糖和果糖含量增加,水溶性阿拉伯木聚糖含量显著提高,分支度显著下降（P＜0.05）。面包搅拌、醒发及烘焙过程中,阿拉伯木聚糖不断溶解,酚类化合物持续释放;富含发酵麦麸的面包中水溶性阿拉伯木聚糖含量及分支度更高。模拟肠、胃消化后,富含发酵麦麸的面包中游离酚和阿魏酸含量更高,且吸收效果好。此外,发酵麦麸显著提高了面包的抗氧化活性。     

Metabolic profile biomarkers of metal contamination in a sentinel terrestrial species are applicable across multiple sites

In this study, we addressed the question of whether an omic approach could genuinely be useful for biomarker profile analysis across different field sites with different physicochemical characteristics. We collected earthworms (Lumbricus rubellus) from seven sites with very different levels of metal contamination and prevailing soil type and analyzed tissue extracts by 1H nuclear magnetic resonance spectroscopy. Pattern recognition analysis of the data showed that both site- and contaminant-specific effects on the metabolic profiles could be discerned. Zinc was identified as the probable major contaminant causing a metabolic change in the earthworms. Individual sites could be resolved on the basis of NMR spectral profiles by principal component analysis; these site differences may also have been caused by additional abiotic factors such as soil pH. Despite an inevitable degree of confounding between site and contaminant concentrations, it was possible to identify metabolites which were correlated with zinc across all different sites. This study therefore acts as a proof of principle for the use of NMR-based metabolic profiling as a diagnostic tool for ecotoxicological research in polluted field soils.     

Effect of sodium citrate plus sodium diacetate or buffered vinegar on quality attributes of enhanced beef top sirloins

As new pathogen intervention products come to market, it is important to ensure that they maintain or improve meat quality. Shelf-life and palatability traits were measured for top sirloins enhanced to 110% with solutions containing 0.5% sodium chloride and 0.4% sodium tripolyphosphate (CNT); CNT with a 1% solution of 80% sodium citrate plus 20% sodium diacetate (SC+D); or CNT with 2% buffered vinegar (VIN) in the final product. Enhancement solution did not influence color over 7days of retail display, except VIN was subjectively more red than CNT and SC+D on d 7 and SC+D had less discoloration than CNT on d 7 (P<0.05). VIN was rated lower (P<0.05) than CNT for trained sensory tenderness and there was no difference in shear force between treatments. SC+D and VIN show promise for use in beef enhancement solutions, however, further sensory studies are warranted.     

Cationic polymerizations at elevated temperatures by novel initiating systems having weakly coordinating counteranions2. Isobutylene/isoprene copolymerizations

As a sequel to our studies on isobutylene (IB) homopolymerizations, we have investigated the copolymerization of IB/isoprene (IP) mixtures containing up to ∼20 mole% IP in the feed by the use of the in situ (CH₃)₃Si[B(C₆F₅)₄] initiating system in close-to-neat monomers in the temperature range from −35 to −8 (reflux)°C. The effects of temperature and IB/IP feed ratio on copolymer molecular weights were determined and compared with those produced by AlCl₃. The molecular weights of butyl rubbers obtained by the novel initiating system under a variety of conditions are invariably and significantly higher than those made with AlCl₃. High molecular weight gel-free rubbers containing up to ∼5 mol% unsaturation can be obtained at relatively high temperatures. Copolymer compositions can be controlled by the IB/IP ratio in the feed. Product molecular weights decrease with increasing IP content. To gain insight into the copolymerization mechanism, the activation enthalpy of molecular weights (ΔH^‡=−5.9 kcal/mol, −24.7 kJ/mol) and the reactivity ratios (r_IB= 1.8, r_IP= 1.5) have been determined. Received: 8 July 1998/Revised version: 16 October 1998/Accepted: 16 October 1998     

Rheological properties of bitumen in water emulsions with added solids

Experimental work was carried out to investigate the rheological properties of bitumen in water emulsions containing solids of different shape and size. The bitumen volumetric concentration was varied up to 60%, solids free basis, and the solids volume fraction (total volume basis) was varied up to 0.2. Irregular-shaped silica sand (average diameter: 9 and 33 μm) and smooth spherical glass beads (average diameter: 27 and 44 μm) were used as the added solids. In the low shear stress range, shear thinning behavior was observed for bitumen in water emulsions. At high shear stress, the viscosity of the emulsions became fairly independent of the shear stress. The addition of solids to the bitumen emulsions increased the mixture viscosity. The addition of irregular-shaped silica sand gave a higher viscosity than a similar addition of the spherical glass beads. The viscosity of the emulsion/solids mixtures was influenced by the solids size as well; the smaller size particles gave a higher viscosity. The addition of solids to the bitumen emulsions also induced shear thickening (dilatancy) behavior at high solids volume fraction. The degree of the shear thickening increased with the oil concentration.