钻井工程固井胶结界面研究现状

固井质量问题在石油勘探开发中备受关注，对特殊工艺井钻井、油水井开采寿命和勘探开发效益有直接的影响。对固井胶结界面的研究是从根本上提高固井质量的一项基础性研究工作。为了推动固井胶结界面研究工作的开展，分析了国内外近年来有关固井界面研究的文献，阐述了开展固井胶结界面基础研究工作的意义，着重分析了这一研究领域目前所采用的研究方法，以及提高固井界面胶结强度的主要途径。在分析文献的基础上，提出今后深入开展固井界面研究工作的重点是：1）继续完善研究方法；2）重视动态研究；3）从胶结界面的微观结构和钻井工程整体系统的角度开展研究工作；4）注重改善胶结界面水化产物的微观结构和钻井工作液之间的协调增强作用。     

CFG桩法的设计及施工

CFG桩复合地基是一种新型的地基处理技术 ,本文对其作用原因、设计方法、施工及质量检测等方面进行了初步探讨。     

异丁醛氧化制丙酮热导气相色谱分析

本工作用２米４０１有机担体填充柱，在带四臂热导检测器的国产１０３型气相色谱仪上，仅８分钟将原料异丁醛、产物丙酮及水进行良好分离，并采用内标法定量，其最大平均偏差在±２％以内。方法简单、快速、准确     

用废聚苯乙烯塑料制备胶粘剂的综述

废聚苯乙烯泡沫塑料在自然界中不能自然降解而正成为严重的社会公害，其综合利用在当今社会越来越受到重视。本文着重分析了聚苯乙烯塑料在我国的消费状况并阐述了利用废旧泡沫塑料研制和开发各种不同用途胶粘剂的进展     

模糊技术的发展及在相关领域中的应用

本文介绍了模糊技术的发展和现状，以及在相关领域中的应用情况，并且讨论了模糊技术在我国的产业化方向等问题。     

Delta opioid peptide [D-Ala2,D-leu5]enkephalin blocks the long-term loss of dopamine transporters induced by multiple administrations of methamphetamine: involvement of opioid receptors and reactive oxygen species

Delta opioid peptide [D-Ala2,D-leu5]enkephalin (DADLE) can prolong organ preservation and increases myocardial tolerance to ischemia. Our study examined the protective property of DADLE against methamphetamine- (METH) induced dopaminergic terminal damage in the central nervous system. Because the neurotoxicity of METH involves reactive oxygen species, we also examined if DADLE might be an antioxidative agent in vitro. DADLE at 2 and 4 mg/kg (i.p.), given 30 min before each METH administration (5 or 10 mg/kg, i.p., four injections in a day at 2-hr intervals), dose-dependently blocked the METH-induced long-term dopamine transporter loss. The opioid antagonist naltrexone blocked this action of DADLE in both aspects of striata but tends not to affect the effects of DADLE in the nucleus accumbens. DADLE did not alter changes in body temperature induced by METH. The reduction of striatal dopaminergic content and tyrosine hydroxylase activity caused by METH, however, were not blocked by DADLE. In vitro, DADLE was approximately equipotent to glutathione in inhibiting both superoxide anion formation induced by xanthine oxidase and hydroxyl radical formation evoked by ferrous/citrate complex. DADLE was only slightly less potent than glutathione in inhibiting the iron/ascorbate-induced brain lipid peroxidation. These results suggest that DADLE can protect the terminal membranes of dopaminergic neurons against METH-induced insult but not the loss of dopaminergic content and tyrosine hydroxylase activity and that this action of DADLE might involve opioid receptors as well as the sequestration of free radical.     

One-stage sternal stenting with homograft bone after cardiac operation in pediatric patients

Low cardiac output after open heart operations in neonates and infants carries a high mortality. Delayed sternal closure may be life-saving but may prolong hospital stay and increase costs. To circumvent these issues, we shaped homograft bone and interposed it between the sternal edges to allow primary wound closure in 2 pediatric patients. Midterm results are satisfactory.     

Sequencing of two alternatively spliced mRNAs corresponding to the extracellular domain of the rat receptor for advanced glycosylation end products (RAGE)

The phosphorylation of glucose to glucose-6-phosphate, catalyzed by hexokinase, is the first committed step in glucose uptake into skeletal muscle. Two isoforms of hexokinase, HKI and HKII, are expressed in human skeletal muscle, but only HKII expression is regulated by insulin. HKII messenger RNA, protein, and activity are increased after 4 h of insulin infusion; however, glucose uptake is stimulated much more rapidly, occurring within minutes. Studies in rat muscle suggest that changes in the subcellular distribution of HKII may be an important regulatory factor for glucose uptake. The present studies were undertaken to determine if insulin causes an acute redistribution of HKII activity in human skeletal muscle in vivo. Muscle biopsies (vastus lateralis muscle) were performed before and at the end of 30 min insulin infusion, performed using the euglycemic clamp technique. Muscle biopsies were subfractionated into soluble and particulate fractions to determine if insulin acutely changes the subcellular distribution of HKII. Insulin decreased HKII activity in the soluble fraction from 2.20 +/- 0.31 to 1.40 +/- 0.18 pmoles/(min[chempt]micrograms) and increased HKII activity in the particulate fraction from 3.02 +/- 0.46 to 3.45 +/- 0.46 pmoles/(min[chempt]micrograms) (P < 0.01 for both). These changes in HKII activity were correlated with changes in HKII protein, as determined by immunoblot analysis (r = 0.53, P = 0.05). Insulin had no effect on the subcellular distribution of HKII activity, which was primarily restricted to the soluble fraction. These studies are consistent with the conclusion that, in vivo in human skeletal muscle, insulin changes the subcellular distribution of HKII within 30 min.     

Hybrid integrator backstepping control of robotic manipulators driven by brushless DC motors

In this paper, a hybrid integrator backstepping controller is proposed for robotic manipulators actuated with brushless DC motors in the presence of arbitrary uncertain inertia parameters of the manipulator and the electrical parameters of the actuators. The main features are: 1) the design, requiring at most the joint velocities and stator currents feedback; 2) the semiglobal asymptotic stability of the controller being established in the Lyapunov sense; and 3) suitability of the scheme for multijoint robots. Simulation results are included to demonstrate the tracking performance.