Free-living inferential modeling of blood glucose level using only noninvasive inputs

The goal of this work is to present a causation modeling methodology with the ability to accurately infer blood glucose levels using a large set of highly correlated noninvasive input variables over an extended period of time. These models can provide insight to improve glucose monitoring, and glucose regulation through advanced model-based control technologies. The efficacy of this approach is demonstrated using real data from a type 2 diabetic (T2D) subject collected under free-living conditions over a period of 25 consecutive days. The model was identified and tested using eleven variables that included three food variables as well as several activity and stress variables. The model was trained using 20 days of data and validated using 5 days of data. This gave a fitted correlation coefficient of 0.70 and an average absolute error (AAE) (i.e., the average of the absolute values for the measured glucose concentration minus modeled glucose concentration) of 13.3 mg/dL for the validation data. This AAE result was significantly better than the subject’s personal glucose meter AAE of 15.3 mg/dL for replicated measurements.     

Robust multiscale stereo matching from fundus images with radiometric differences

A robust multiscale stereo matching algorithm is proposed to find reliable correspondences between low contrast and weakly textured retinal image pairs with radiometric differences. Existing algorithms designed to deal with piecewise planar surfaces with distinct features and Lambertian reflectance do not apply in applications such as 3D reconstruction of medical images including stereo retinal images. In this paper, robust pixel feature vectors are formulated to extract discriminative features in the presence of noise in scale space, through which the response of low-frequency mechanisms alter and interact with the response of high-frequency mechanisms. The deep structures of the scene are represented with the evolution of disparity estimates in scale space, which distributes the matching ambiguity along the scale dimension to obtain globally coherent reconstructions. The performance is verified both qualitatively by face validity and quantitatively on our collection of stereo fundus image sets with ground truth, which have been made publicly available as an extension of standard test images for performance evaluation.     

The experience of enchantment in human–computer interaction

Improving user experience is becoming something of a rallying call in human–computer interaction but experience is not a unitary thing. There are varieties of experiences, good and bad, and we need to characterise these varieties if we are to improve user experience. In this paper we argue that enchantment is a useful concept to facilitate closer relationships between people and technology. But enchantment is a complex concept in need of some clarification. So we explore how enchantment has been used in the discussions of technology and examine experiences of film and cell phones to see how enchantment with technology is possible. Based on these cases, we identify the sensibilities that help designers design for enchantment, including the specific sensuousness of a thing, senses of play, paradox and openness, and the potential for transformation. We use these to analyse digital jewellery in order to suggest how it can be made more enchanting. We conclude by relating enchantment to varieties of experience.An earlier version of this paper was presented at Chi’2004 Fringe.     

Collection and transfusion of blood and blood components in the United States, 1989

A poor response to L-DOPA in addition to parkinsonian, cerebellar, and autonomic signs is commonly regarded as indicative of clinical multiple system atrophy (MSA). We compared the motor response to a single oral administration of 250 mg L-DOPA/25 mg carbidopa in eight MSA patients and eight Parkinson's disease (PD) patients with the "on-off" phenomenon, evaluating L-DOPA peripheral pharmacokinetics. Motor response was consistently good in all PD patients, but only four MSA patients had a (moderate) response. Pharmacokinetic parameters did not differ between the groups. The varying extent of putaminal damage could be responsible for the differing motor response to L-DOPA in MSA patients.     

Differential Fos Expression Following Aspiration, Electrolytic, or Excitotoxic Lesions of the Perirhinal Cortex in Rats.

The authors explored the possibility that there are different neural consequences, beyond the primary site of brain damage, following perirhinal cortex (PRh) lesions made in different ways. Fos expression was used as a marker for neuronal activation and compared across the forebrains of rats that underwent the different types of surgery. Electrolytic and excitotoxic PRh lesions produced dramatic increases in Fos expression in the cortex, and excitotoxic and aspiration PRh lesions increased Fos expression in the dentate gyrus. These data are consistent with the hypothesis that different lesion methods have separable effects on neural function in regions outside the lesion site that could account for inconsistencies in the literature regarding the behavioral effects of PRh lesions on tests of spatial memory. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Energy-efficient induction motors performance characteristics andlife-cycle cost comparisons for centrifugal loads

When fixed-speed motors (fed directly at power frequency) are purchased for new installations or for replacements, the loaded shaft speed differences among motor options are either ignored or overestimated. The most common first-cut estimate is that the consumed shaft power will vary as the cube of the ratio of the motor rated nameplate speeds for centrifugal driven loads that have discharge control valves (on pressure or now control). In actuality, this is true only if the motors are loaded at approximately nameplate output. This paper discusses the true “control valve loss” factor taking into account actual speed differences among motor options. A simplified equation and figure are presented to permit quick evaluation of motor purchase alternatives for the lowest life-cycle cost based on efficiency and rated-load speed differences. NEMA standards on slip-speed variation should be made more stringent to increase the validity of speed-difference loss evaluations. Additionally, efficiency test results and loaded speed measurements for standard-efficiency and premium-efficiency 10 and 100 hp motors are presented, leading to a conclusion that standard-efficiency motors should be operated at no higher than rated voltage and that premium-efficiency motors should he operated at 5%-10% above rated voltage for best system efficiency     

Modeled and measured instruction fetching performance forsuperscalar microprocessors

Instruction fetching is critical to the performance of a superscalar microprocessor. We develop a mathematical model for three different cache techniques and evaluate its performance both in theory and in simulation using the SPEC95 suite of benchmarks. In all the techniques, the fetching performance is dramatically lower than ideal expectations. To help remedy the situation, we also evaluate its performance using prefetching. Nevertheless, fetching performance is fundamentally limited by control transfers. To solve this problem, we introduce a new fetching mechanism called a dual branch target buffer. The dual branch target buffer enables fetching performance to leap beyond the limitation imposed by conventional methods and achieve a high instruction fetching rate     

Reasons for drop in shell-and-tube condenser performance when replacing R22 with zeotropic mixtures. Part 1. Analysis of experimental findings

An experimental and theoretical investigation was made to find out the reasons for the drop in shell-and-tube condenser performance when replacing R22 with a zeotropic mixture R407C. Measurements show that at lower condenser loads the reduction in performance can be as large as 70% compared to the full condenser load. Calculation results are compared with experimental results for two different condensers, one with micro-finned tubes and one with 3-D finned tubes. Calculations show that the degree of mixing of the newly formed condensate on a tube and the drained condensate is a factor influential enough to explain the performance drop. 3-D finned tubes seem to have better mixing in the condensate than integral finned tubes.     

Agile workforce evaluation: a framework for cross-training and coordination

This paper outlines approaches for assessing and classifying manufacturing and service operations in terms of their suitability for use of cross-trained (flexible) workers. We refer to our overall framework as agile workforce evaluation. The primary contributions of this paper are: (i) a strategic assessment framework that structures the key mechanisms by which cross-training can support organizational strategy; (ii) a tactical framework that identifies key factors to guide the selection of an architecture and worker coordination policy for implementing workforce agility; (iii) a classification of workforce agility architectures; (iv) a survey of a broad range of archetypical classes of worker coordination policies; (v) a survey of the literature with an operational perspective on workforce agility; and (vi) identification of opportunities for research and development of architectures for specific production environments.