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71.
72.
小河嘴水电站已运行四十多年,设备老化,故障多,自动化水平低,对该站进行增效扩容改造是必要的,而且也是可行的。  相似文献   
73.
74.
Mixed transition metal oxides (MTMOs) have received intensive attention as promising anode materials for lithium-ion batteries (LIBs) and sodium-ion batteries (SIBs). In this work, we demonstrate a facile one-step water-bath method for the preparation of graphene oxide (GO) decorated Fe2(MoO4)3 (FMO) microflower composite (FMO/GO), in which the FMO is constructed by numerous nanosheets. The resulting FMO/GO exhibits excellent electrochemical performances in both LIBs and SIBs. As the anode material for LIBs, the FMO/GO delivers a high capacity of 1,220 mAh·g–1 at 200 mA·g–1 after 50 cycles and a capacity of 685 mAh·g–1 at a high current density of 10 A·g–1. As the anode material for SIBs, the FMO/GO shows an initial discharge capacity of 571 mAh·g–1 at 100 mA·g–1, maintaining a discharge capacity of 307 mAh·g–1 after 100 cycles. The promising performance is attributed to the good electrical transport from the intimate contact between FMO and graphene oxide. This work indicates that the FMO/GO composite is a promising anode for high-performance lithium and sodium storage.
  相似文献   
75.
As an attractive alternative to plasmid DNA, messenger RNA (mRNA) has recently emerged as a promising class of nucleic acid therapeutics for biomedical applications. Advances in addressing the inherent shortcomings of mRNA and in the development of nanoparticle-based delivery systems have prompted the development and clinical translation of mRNA-based medicines. In this review, we discuss the chemical modification strategies of mRNA to improve its stability, minimize immune responses, and enhance translational efficacy. We also highlight recent progress in nanoparticle-based mRNA delivery. Considerable attention is given to the increasingly widespread applications of mRNA nanomedicine in the biomedical fields of vaccination, protein-replacement therapy, gene editing, and cellular reprogramming and engineering.  相似文献   
76.
Zan  Wu  Zhang  Qiaochu  Xu  Hu  Liao  Fuyou  Guo  Zhongxun  Deng  Jianan  Wan  Jing  Zhu  Hao  Chen  Lin  Sun  Qingqing  Ding  Shijin  Zhou  Peng  Bao  Wenzhong  Zhang  David Wei 《Nano Research》2018,11(7):3739-3745
Nano Research - A spin-coating method was applied to obtain thinner and smoother PEO/LiClO4 polymer electrolyte films (EFs) with a lower level of crystallization than those obtained using a...  相似文献   
77.
Jiang  Lei  Ding  Yang  Xue  Xialin  Zhou  Sensen  Li  Cheng  Zhang  Xiaoke  Jiang  Xiqun 《Nano Research》2018,11(11):6062-6073
Nano Research - Developing multifunctional nanoparticles to support new therapy models is a promising and challenging task to address the current dilemma on antitumor treatment. Herein, we...  相似文献   
78.
Li  Dongyu  Ni  Xiang  Zhang  Xiaoyan  Liu  Liwei  Qu  Junle  Ding  Dan  Qian  Jun 《Nano Research》2018,11(11):6023-6033
Nano Research - Aggregation-induced emission luminogens (AIEgens) are fluorescent agents that are ideal for bioimaging and have been widely used for organelle targeting, cellular mapping, and...  相似文献   
79.
BACKGROUND AND PURPOSE: Mood disorders are common after stroke and may impede physical, functional, and cognitive recovery, making early identification and treatment of potential importance. We aimed to compare the accuracy of the General Health Questionnaire (GHQ-30) and the Hospital Anxiety and Depression (HAD) Scale in detecting psychiatric morbidity after stroke and to determine the most suitable cutoff points for different purposes. METHODS: One hundred five hospital-referred stroke patients completed both the GHQ-30 and HAD Scale 6 months after onset before a blinded psychiatric assessment in which the Schedule for Affective Disorders and Schizophrenia with some supplementary questions was used to determine a DSM-IV (Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition) diagnosis. Measures were compared in terms of sensitivity, specificity, and receiver operating characteristic curves. RESULTS: No significant differences were found between the GHQ-30 and the HAD Scale in identifying those patients with any DSM-IV diagnosis (P=0.95), grouped depression (P=0.56), or anxiety (P=0.25) disorders. The previously recommended cutoff points for identifying "cases" for the GHQ (4/5) and for the HAD Scale (8/9 and 11/12) were found to be suboptimal in this population. CONCLUSIONS: The GHQ-30 and HAD scale exhibited similar levels of sensitivity and specificity. Data are presented, taking into account the "cost" of false-positives and negatives, to allow a choice of cutoff points suitable for differing situations.  相似文献   
80.
电路的任意激励的零状态响应,可以用卷积积分和拉普拉斯交换的方法求解。本文通过两个一阶电路的实例,阐述了两种方法的应用特点。  相似文献   
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