Geographic constraints on passive solar domestic hot water systems due to pipe freezing

The supply and return piping of passive solar domestic hot water systems (SDHWS) is typically exposed to ambient weather conditions, and damaging pipe freeze is a major concern. This paper presents a pipe-freeze model that accounts for hot water draws and uses 30 years of actual weather data. The simulation results are cast in terms of pipe-freeze probabilities. Using contour maps of the continental United States, the pipe-freeze probabilities for residential, commercial, and seasonal passive SDHWS are presented for various pipe and insulation geometries.     

Starting up the Sherritt Zinc Pressure Leach Process at Hudson Bay

The first commercial application of the Sherritt two-stage zinc pressure leach process commenced operation at the Hudson Bay Mining and Smelting Company metallurgical complex in Flin Flon, Manitoba (Canada), on July 2, 1993. The start-up was relatively smooth, and full design rate for the plant was achieved by September 12, 1993. Since that time, zinc extraction in the zinc pressure leach plant has consistently been in excess of 98%, and production has continued to exceed expectations. The successful operation of the Hudson Bay plant represents a significant advancement of zinc processing technology, especially with respect to meeting the environmental challenge faced by zinc plants today.     

Successful engraftment of haploidentical stem cell transplant for familial haemophagocytic lymphohistiocytosis using both bone marrow and peripheral blood stem cells

Familial haemophagocytic lymphohistiocytosis (HLH) is a disease with a very poor prognosis unless patients receive a bone marrow transplant. It is often difficult to find an HLA-matched donor and haploidentical familial donors may be considered. The main complication of this type of transplant is graft rejection. We describe a patient with familial HLH who received a haploidentical transplant using both mobilized peripheral blood and bone marrow stem cells in an attempt to overcome graft rejection by increasing the stem cell dose. The peripheral blood stem cell inoculum was CD34 enriched using a Cellpro column and T-cell depleted by Campath-1M, the patient received conditioning for a matched sibling donor transplant with the addition of Campath 1G. There was rapid and full engraftment and the patient remains disease free at 5 months. This technique may be applicable for other fatal inborn errors in the absence of an HLA-matched donor.     

Self-disclosure and liking: A meta-analytic review.

Self-disclosure plays a central role in the development and maintenance of relationships. One way that researchers have explored these processes is by studying the links between self-disclosure and liking. Using meta-analytic procedures, the present work sought to clarify and review this literature by evaluating the evidence for 3 distinct disclosure-liking effects. Significant disclosure-liking relations were found for each effect: (1) People who engage in intimate disclosures tend to be liked more than people who disclose at lower levels, (2) people disclose more to those whom they initially like, and (3) people like others as a result of having disclosed to them. In addition, the relation between disclosure and liking was moderated by a number of variables, including study paradigm, type of disclosure, and gender of the discloser. Taken together, these results suggest that various disclosure-liking effects can be integrated and viewed as operating together within a dynamic interpersonal system. Implications for theory development are discussed, and avenues for future research are suggested. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Wood adhesives based on tannin extracts from barks of some pine and spruce species

Barks available in commercial quantities in Australia and overseas have been examined for their efficacy as raw materials for conversion to high quality adhesives for reconstituted wood products. Previously bark from maturePinus radiata was found to be suitable. This paper examines the suitability of barks from four mature pine species (Pinus caribaea, Pinus elliottii, Pinus pinaster andPinus sylvestris), one young pine species (Pinus radiata) and one spruce species (Picea abies). Only the bark extracts ofPinus caribaea andPinus pinaster gave high quality (Type A bond, WBP) wood adhesives. The gluing properties of the adhesives derived from the extracts appeared to be dependent on their contents of formaldehyde-reactive polyflavanoids as indicated by their Stiasny values, with a value of 65% being the minimum for producing a high quality adhesive by the methods used.     

The UCLA Multidimensional Condom Attitudes Scale: Documenting the complex determinants of condom use in college students.

Describes the development and validation of the UCLA Multidimensional Condom Attitudes Scale (MCAS). The relationships between the MCAS and gender, sexual experience, intentions to use a condom, and past condom use were assessed. The MCAS has 5 distinct factors: (1) Reliability and Effectiveness of condoms, (2) the sexual Pleasure associated with condom use, (3) the stigma attached to persons who use condoms (Identity Stigma), (4) the Embarrassment About Negotiation and Use of condoms, and (5) the Embarrassment About the Purchase of condoms. Results strongly suggest that condom attitudes are multidimensional and thus cannot meaningfully be summed to a single global score. Results further indicate that men and women hold very different attitudes toward condoms. Implications of scale multidimensionality and directions for future research are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Individuation, peers, and adolescent alcohol use: A latent growth analysis.

The study used latent growth modeling to investigate longitudinal relationships between individuation, peer alcohol use, and adolescent alcohol use among African American, Mexican American, and non-Hispanic White adolescents (N=6,048) from 7th, 8th, and 9th grades over a 3-year period. Initial levels of peer alcohol use were significantly related to changes in adolescents' alcohol use, whereas initial adolescent alcohol use also significantly related to changes in peers' alcohol use, suggesting a bidirectional relationship. Higher levels of intergenerational individuation were related to smaller increases in adolescent alcohol use and higher levels of separation were related to larger increases in youth drinking. The findings were similar across ethnic groups. Implications for development of prevention and intervention programs are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Multifunctional hydrogels that promote osteogenic hMSC differentiation through stimulation and sequestering of BMP2

The extracellular environment controls many cellular activities thereby linking external material cues to internal cell function. By better understanding these processes, synthetic extracellular material niches can be tailored to present cells with highly regulated physical and/or chemical cues that promote or suppress selected cell functions. Here, poly(ethylene glycol) (PEG) hydrogels were functionalized with fluvastatin-releasing grafts and growth factor binding heparin domains to enable the dynamic exchange of information between the material and cells from the outside-in and inside-out (i.e., bidirectional signaling). By incorporating a fluvastatin-releasing graft and carefully controlling the dose and temporal release, materials were designed to promote bone morphogenic protein (BMP2) and alkaline phosphatase (ALP) production by human mesenchymal stem cells (hMSCs). When the release of fluvastatin was controlled to occur over 2 weeks, BMP2 and ALP production was increased 2.2-fold and 1.7-fold, respectively, at day 28 compared to hMSCs cultured in the absence of fluvastatin. By introducing a heparin functionality into the gel to sequester and localize the hMSC-produced BMP2, the osteogenic differentiation of hMSCs was further augmented over fluvastatin delivery alone. Osteopontin and core binding factor α1 gene expression was 6-fold and 4-fold greater for hMSCs exposed to fluvastatin in the presence of the heparin functionalities, respectively. These results demonstrate how multifunctional gels that interact with cells in a bidirectional manner can efficiently promote selected cell functions, such as the osteogenic differentiation of hMSCs.     

Finding feasible mold parting directions using graphics hardware

We present new programmable graphics hardware accelerated algorithms to test the 2-moldability of geometric parts and assist with part redesign. These algorithms efficiently identify and graphically display undercuts as well as minimum and insufficient draft angles. Their running times grow only linearly with respect to the number of facets in the solid model, making them efficient subroutines for our algorithms that test whether a tessellated CAD model can be manufactured in a two-part mold. We have developed and implemented two such algorithms to choose candidate directions to test for 2-moldability using accessibility analysis and Gauss maps. The efficiency of these algorithms lies in the fact that they identify groups of candidate directions such that if any one direction in the group is undercut-free, all are, or if any one is not undercut-free, none are. We examine trade-offs between the algorithms' speed, accuracy, and whether they guarantee that an undercut-free direction will be found for a part if one exists.