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41.
In this paper we describe continuing work being carried out as part of the Bristol Wearable Computing Initiative. We are
interested in the use of context sensors to improve the usefulness of wearable computers. A CyberJacket incorporating a Tourist Guide application has been built, and we have experimented with location and movement sensing devices
to improve its performance. In particular, we have researched processing techniques for data from accelerometers which enable
the wearable computer to determine the user’s activity. We have experimented with, and review, techniques already employed
by others; and then propose new methods for analysing the data delivered by these devices. We try to minimise the number of
devices needed, and use a single X-Y accelerometer device. Using our techniques we have adapted our CyberJacket and Tourist
Guide to include a multimedia presentation which gives the user information using different media depending on the user’s
activity as well as location. 相似文献
42.
de Boer AR Letzel T van Elswijk DA Lingeman H Niessen WM Irth H 《Analytical chemistry》2004,76(11):3155-3161
Liquid chromatography (LC) was coupled on-line to a continuous-flow enzymatic assay using electrospray ionization mass spectrometry (ESI-MS) as readout for the screening of enzyme inhibitors in complex samples. Inhibitors were detected by changes in the concentration of the enzymatic reaction products, indicating the inhibition of enzymatic activity. The molecular masses of the inhibitors were determined with high certainty by using retention time matching and peak shape comparison. Due to the high matching accuracy, baseline separation of coeluting analytes was not necessary in order to identify the correct masses of the bioactive compounds. The continuous-flow system was successfully applied for the screening of complex samples, such as natural extracts. For a red clover extract, detection limits of 0.3-0.8 micromol/L were obtained. System validation was performed by determining the IC(50) values of four inhibitors in the flow-injection mode. The IC(50) values were in the 0.11-5.6 micromol/L range and correspond closely to data obtained by microtiter plate assays. Detection limits were in the range of 0.018-0.35 micromol/L in the flow-injection mode, and 0.075-0.75 micromol/L in the LC mode. These values are well below the typical compound concentrations (1-10 micromol/L) used in high-throughput screening. Together with an interday precision of 12.6%, these results demonstrate the applicability of the system for bioactivity screening of complex mixtures, generating both chemical and biological information on bioactive compounds in a single run. 相似文献
43.
Computer-controlled mechanical simulation of the artificially ventilated human respiratory system 总被引:3,自引:0,他引:3
Mesić S Babuska R Hoogsteden HC Verbraak AF 《IEEE transactions on bio-medical engineering》2003,50(6):731-743
A mechanical lung simulator can be used to simulate specific lung pathologies, to test lung-function equipment, and in instruction. A new approach to mechanical simulation of lung behavior is introduced that uses a computer-controlled active mechatronic system. The main advantage of this approach is that the static and dynamic properties of the simulator can easily be adjusted via the control software. A nonlinear single-compartment mathematical model of the artificially ventilated respiratory system has been derived and incorporated into the simulator control system. This model can capture both the static and dynamic compliance of the respiratory system as well as nonlinear flow-resistance properties. Parameters in this model can be estimated by using data from artificially ventilated patients. It is shown that the simulation model fits patient data well. This mathematical model of the respiratory system was then matched to a model of the available physical equipment (the simulator, actuators, and the interface electronics) in order to obtain the desired lung behavior. A significant time delay in the piston motion control loop has been identified, which can potentially cause oscillations or even instability for high compliance values. Therefore, a feedback controller based on the Smith-predictor scheme was developed to control the piston motion. The control system, implemented on a personal computer, also includes a user-friendly interface to allow easy parameter setting. 相似文献
44.
How effective is intermittent chlorination to control adult mussel fouling in cooling water systems? 总被引:6,自引:0,他引:6
Mussel control in cooling water systems is generally achieved by means of chlorination. Chlorine is applied continuously or intermittently, depending on cost and discharge criteria. In this paper, we examined whether mussels will be able to survive intermittent chlorination because of their ability to close their valves during periods of chlorination. Experiments were carried out using three common species of mussels: a freshwater mussel, Dreissena polymorpha, a brackish water mussel, Mytilopsis leucophaeata and a marine mussel, Mytilus edulis. The mussels were subjected to continuous or intermittent (4 h chlorination followed by 4 h no chlorination) chlorination at concentrations varying from 1 to 3 mg l(-1) and their responses (lethal and sublethal) were compared to those of control mussels. In addition, shell valve activity of mussels was monitored using a Mussel-monitor. Data clearly indicate that mussels shut their valves as soon as chlorine is detected in the environment and open only after chlorine dosing is stopped. However, under continuous chlorination mussels are constrained to keep the shell valves shut continuously. The mussels subjected to continuous chlorination at 1 mg l(-1) showed 100% mortality after 588 h (D. polymorpha), 966 h (Mytilus edulis) and 1104 h (Mytilopsis leucophaeata), while those subjected to intermittent chlorination at 1 mg l(-1) showed very little or no mortality during the same periods. Filtration rate, foot activity index and shell valve movement of D. polymorpha, Mytilopsis leucophaeata and Mytilus edulis decreased more than 90% at 1 mg l(-1) chlorine residual when compared to control. However, mussels subjected to intermittent chlorination showed a similar reduction (about 90%) in filtration rate, foot activity index and shell valve movement during chlorination and 3% during breaks in chlorination. The data indicate that intermittent chlorination between 1 and 3 mg l(-1) applied at 4 h on and 4 h off cycle is unlikely to control biofouling if mussels are the dominant fouling organisms. 相似文献
45.
This paper considers the problem of output feedback trajectory tracking with a unicycle mobile robot system. A state-feedback controller for the non-linear error dynamics of the robot is combined with an observer that estimates the orientation error based on available trajectory information and measurement of the position coordinates. A stability analysis, derivation and implementation of the resulting controller is given and tested on an experimental mobile robot. 相似文献
46.
47.
48.
Zhang Tianci Wang Haitao Li Zhengcao Schut Henk Zhang Zhengming He Ming Sun Yuliang 《金属学报》2018,(4):512-518
The reactor pressure vessel (RPV) is the key component in the nuclear power plant, which is considered irreplaceable and can be the life-limiting feature of the operation of nuclear power plant if its mechanical properties degrade sufficiently. High temperature gas-cooled reactor (HTGR) has perfect inherent safety, which is intended to be one of the fourth generation advanced nuclear reactors. However, HTGR has different service temperature with pressurized water reactor (PWR), that the service temperature of HTGR is 250 degrees C and that of PWR is 290 degrees C. So the irradiation behaviour of RPV in HTGR is expected to be investigated. In this wok, 3 MeV Fe-ion irradiation was performed on Chinese A508-3 reactor pressure vessel steel which is employed by high-temperature gas-cooled reactors and pure Fe under room temperature (about 25 degrees C) and high temperature (250 degrees C). The ion doses were 0.1, 0.5 and 1.0 dpa for both room temperature irradiation and high temperature irradiation. SRIM modeling was performed before irradiation experiments to guide the experimental details. Positron annihilation Doppler broadening (PADB) spectroscopy experiments and nano-indentation tests (to study embrittlement behavior) were conducted for characterization. It is found that after both room temperature irradiation and high temperature irradiation, the densities of defects in the reactor pressure vessel steel and pure Fe increase, and the type of defects could be vacancy-type and solute cluster type from PADB results. The vacancy-type defect density under high temperature irradiation is lower than that under room temperature irradiation. That is because high temperature can recover the defects formed during irradiation. The hardness test results show that for both the reactor pressure vessel steel and pure Fe, the irradiation hardening increases with increasing dose. Compared to room temperature irradiation, high temperature irradiation can produce more solute clusters and fewer vacancy-type defects in the reactor pressure vessel steel. So the irradiation hardening of the reactor pressure vessel steel might be caused mainly by the formation of solute clusters. 相似文献
49.
Algorithms for calculating the emitter hole and electron currents in the case of an n+n? epitaxial emitter have been published by Yu [2] and Rofail et al. [3]. Both algorithms are restricted to a small ratio of hole to electron current whereas Yu's algorithm is further restricted by the assumption of a constant electric field in the epilayer.In the present paper an algorithm is presented in which both restrictions have been removed and which is valid from low through high injection. The assumption of quasineutrality in the epilayer, which is used in the present algorithm, is veryfied using Adlers criterium [4]. Calculation results are presented for a structure treated by Poorter [1] and a comparison is made with his results. 相似文献
50.