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排序方式: 共有498条查询结果,搜索用时 15 毫秒
491.
The high-temperature oxidation behavior of pure Ni in air and Ar with and without 30?vol%H2O at 1,000?°C was investigated to understand the effects of water–vapor on the resulting oxidation kinetics and scale structures. It was found that water–vapor significantly affected the morphology and scale structure of NiO. A duplex NiO scale with a powder-like outer and dense inner NiO layer developed when the Ni was oxidized in atmospheres containing water–vapor. The grain size of the dense inner NiO layer was much smaller than that formed in dry atmospheres. The growth of the powder-like NiO required outward diffusion of Ni and its continued formation occurred at the interface between the powder and dense NiO layers. The dense inner NiO layer grew outward and incorporated the powder-like NiO particles and the resulting grain size of the inner layer was smaller in the presence of water–vapor. The water–vapor is speculated to have prevented sintering of NiO particles during growth of the NiO scale. 相似文献
492.
493.
Teramoto K Sato H Sun L Torimura M Tao H Yoshikawa H Hotta Y Hosoda A Tamura H 《Analytical chemistry》2007,79(22):8712-8719
A new method for phylogenetic classification of bacterial strains using matrix-assisted laser desorption/ionization-mass spectrometry (MALDI-MS) is proposed. This method was developed using a bioinformatics-based approach to the rapid identification of bacteria as previously proposed by Demirev and co-workers, which uses ribosomal proteins composed of approximately 50 subunit proteins as biomarkers. Although the amino acid sequences of ribosomal proteins are highly conserved, slight sequence variations can occur at the strain level. Since ribosomal subunit proteins are a complex of housekeeping proteins that have different phylogenetic evolution rates, sequence variation detected as mass differences by MALDI-MS may be useful for the phylogenetic classification of bacteria at strain level. In our proposed method, the first step is the selection of reliable biomarkers through characterization of the expressed ribosomal subunit proteins of a reference strain (usually a genome-sequenced strain) by MALDI-MS. The observed masses in the MALDI mass spectra of cell lysates of sample strains are then compared with the biomarker masses of the reference strain. The biomarkers for each sample strain were designated as present or absent at the reference masses, indicated by 1 or 0, respectively, which were summarized in a table. This table is processed by cluster analysis, generating a phylogenetic tree. In this study, the success of this approach was confirmed by classification of Pseudomonas putida strains because its classification is much more complicated than that of other bacterial strains. Forty-three reliable biomarkers were selected from ribosomal sub-unit proteins of a genome-sequenced strain, P. putida KT2440. The numbers and kinds of biomarkers observed for 16 strains of P. putida, including different biovars, were markedly different, reflecting the variety of the strains. The classification results by the proposed method were highly comparable to those based on the DNA gyrase subunit B gene (gyrB) sequence analysis, suggesting our proposed method would be a useful high-throughput method for phylogenetic classification of newly isolated bacteria. 相似文献
494.
Miyamoto M. Toyota K. Seki K. Nagano T. 《Electron Devices, IEEE Transactions on》1999,46(8):1699-1704
A new CMOS structure has been developed that is distinguished by its asymmetrically doped buried layer (ADB). This structure makes it possible to achieve high drain output resistance and high transconductance necessary for high-performance analog circuits with a low-voltage power supply. The ADB structure has a high-impurity-concentration “pocket” layer near the channel edge of the buried layer only on the source side and a low-impurity surface region through the channel. The source-side channel region determines the threshold voltage and the drain-side channel region absorbs the drain potential. The low-impurity surface region reduces impurity scattering and enables high transconductance. The fabricated ADB CMOS structure increased the drain output resistance, transconductance, and saturation current down to a 0.3-μm channel length, as compared to a control structure. Furthermore, the drain junction capacitance was reduced because of the low impurity concentration beneath the drain region 相似文献
495.
FU Yuan-yong ZHOU Shu-hua T. Koike S. Kinoshita Y. Ma Y. Miura K. Miwa Y. Miyagi K. Shirotori T. Suzuki H. Tamura K. Tsukada M. Ukai K. Futatsukawa K. Hosomi M. Kawai M. Mimori N. Terada N. Maruyama K. Aoki H. Fujioka Y. Kakiguchi T. Nagae D. Nakajima H. Noumi T. Takahashi T. N. Takahashi A. Toyota M. Dairaku T. Fukuda S. Minami W. Irnoto S. Ajimura K. Tanida 《中国原子能科学研究院年报》2007,(1)
496.
F Ikehata J Satoh K Nata A Tohgo T Nakazawa I Kato S Kobayashi T Akiyama S Takasawa T Toyota H Okamoto 《Canadian Metallurgical Quarterly》1998,102(2):395-401
Cyclic ADP-ribose (cADPR) has been shown to be a mediator for intracellular Ca2+ mobilization for insulin secretion by glucose in pancreatic beta cells, and CD38 shows both ADP-ribosyl cyclase to synthesize cADPR from NAD+ and cADPR hydrolase to hydrolyze cADPR to ADP-ribose. We show here that 13.8% of Japanese non-insulin-dependent diabetes (NIDDM) patients examined have autoantibodies against CD38 and that the sera containing anti-CD38 autoantibodies inhibit the ADP-ribosyl cyclase activity of CD38 (P = 0.05). Insulin secretion from pancreatic islets by glucose is significantly inhibited by the addition of the NIDDM sera with anti-CD38 antibodies (P = 0.04-0.0001), and the inhibition of insulin secretion is abolished by the addition of recombinant CD38 (P = 0.02). The increase of cADPR levels in pancreatic islets by glucose was also inhibited by the addition of the sera (P = 0.05). These results strongly suggest that the presence of anti-CD38 autoantibodies in NIDDM patients can be one of the major causes of impaired glucose-induced insulin secretion in NIDDM. 相似文献
497.
Hideaki Hamada Nobuyuki Matsubayashi Hiromichi Shimada Yoshiaki Kintaichi Takehiko Ito Akio Nishijima 《Catalysis Letters》1990,5(2):189-196
XANES and EXAFS analysis of Cu ion-exchanged ZSM-5 zeolite, a highly active catalyst for NO decomposition, is performed. The copper species in the zeolite are Cu(II) ions in the zeolite cages. The contribution of Cu-Cu local structure is suggested for high loading samples. The Cu atoms in the zeolite are more ionic than CuO. The analysis of the catalyst deactivated by SOx treatment suggests the presence of Cu atoms surrounded by SO4 ions which blocks the adsorption of NO molecules. 相似文献
498.
H Suzuki T Shimosegawa A Satoh K Kimura S Ohara S Asaki T Toyota 《Canadian Metallurgical Quarterly》1997,32(6):726-733
To investigate cytoprotection against mucosal injuries of the stomach in patients with diabetes, we investigated gastric mucosal blood flow (GMBF), its response to a burn stress, and the involvement of nitric oxide (NO) in streptozotocin (STZ) diabetic rats. GMBF was measured by laser-Doppler velocimetry (LDV) and by the hydrogen gas clearance technique (HGC). The steady-state GMBF of STZ rats decreased according to the duration of diabetes, and insulin treatment blocked this decrease. Burn stress caused a rapid decrease in the GMBF. Reduction of the GMBF and gastric mucosal leakage of Evans blue (EB) after the burn stress were greater in the STZ rats than in the controls, but insulin treatment completely blocked this increase in EB leakage in the STZ rats. There was a significant negative correlation between the percent GMBF 3 h after the burn stress and EB leakage at the same time point. In the controls and the insulin-treated STZ rats, N-nitro-L-arginine (L-NNA), an NO synthase inhibitor, enhanced the decrease in postburn GMBF and EB leakage, but was without effect in the STZ rats. These results suggest that NO may be involved in the regulation of GMBF, and that persistent hyperglycemia may impair this regulation. These findings suggest that patients with diabetes have reduced cytoprotection against a variety of gastric mucosal injuries. 相似文献