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61.
The use of Static Two Phase Locking Protocols (S2PL) for concurrency control in real-time database systems (RTDBS) has received little attention in the past. Actually, real-time S2PL (RT-S2PL) protocols do possess some desirable features making them suitable for RTDBS, especially for distributed real-time database systems (DRTDBS) in which remote locking is required and distributed deadlock is possible. In this paper, different RT-S2PL protocols are proposed. They differ in their methods of reducing the blocking time of higher priority transactions. Their performance is studied and compared with a real-time dynamic two phase locking protocol (RT-D2PL), called Hybrid Two Phase Locking (Hb2PL). The impact of different system and workload parameters, such as mean inter-arrival time of transactions, number of remote lock requests of a transaction, communication overhead for sending messages, and database size on their performance have been examined. The performance results indicate that the RT-S2PL protocols are suitable for DRTDBS in which the proportion of local locks of a transaction is small and the communication overhead for locking is high. 相似文献
62.
Kang K.-D. Son S.H. Stankovic J.A. 《Knowledge and Data Engineering, IEEE Transactions on》2004,16(10):1200-1216
The demand for real-time data services is increasing in many applications including e-commerce, agile manufacturing, and telecommunications network management. In these applications, it is desirable to execute transactions within their deadlines, i.e., before the real-world status changes, using fresh (temporally consistent) data. However, meeting these fundamental requirements is challenging due to dynamic workloads and data access patterns in these applications. Further, transaction timeliness and data freshness requirements may conflict. We define average/transient deadline miss ratio and new data freshness metrics to let a database administrator specify the desired quality of real-time data services for a specific application. We also present a novel QoS management architecture for real-time databases to support the desired QoS even in the presence of unpredictable workloads and access patterns. To prevent overload and support the desired QoS, the presented architecture applies feedback control, admission control, and flexible freshness management schemes. A simulation study shows that our QoS-aware approach can achieve a near zero miss ratio and perfect freshness, meeting basic requirements for real-time transaction processing. In contrast, baseline approaches fail to support the desired miss ratio and/or freshness in the presence of unpredictable workloads and data access patterns. 相似文献
63.
Hyunseok Oh Jisun Kim Hyejeong Son Byeng D. Youn Byung C. Jung 《Structural and Multidisciplinary Optimization》2016,54(6):1527-1541
In recent years, virtual testing has played an increasingly important role in the design and evaluation of engineered products. However, it is challenging to build the highly accurate computational models for virtual testing. Blind and recognized uncertainties are often unintentionally incorporated. These uncertainties consequently decrease the predictive capability of the models. To this end, this paper proposes a systematic approach for model refinement that minimizes the impact of unrecognized blind and recognized epistemic uncertainties in computational modeling. The approach consists of three steps: model invalidity analysis (MIA), development of an invalidity reasoning tree (IRT), and invalidity sensitivity analysis (ISA). First, in the MIA, possible causes that lead to discrepancies between the experimental and simulation responses are identified through brainstorming. Next, the IRT is built using the affinity diagram. It sequentially lists and screens potential candidate issues for model refinement at the stages of conceptual, mathematical, and computational modeling. Finally, the ISA quantifies the effect of incorporating updates in the model to address potential candidate issues with the goal of reducing the impact of the blind and recognized uncertainties. The most critical candidates are determined by using a weighted decision matrix. To demonstrate the effectiveness of the proposed approach, a case study examining a smartphone liquid crystal display fracture is presented. 相似文献
64.
Minh Son Phan Étienne Baudrier Loïc Mazo Mohamed Tajine 《Journal of Mathematical Imaging and Vision》2017,57(2):164-182
This paper introduces a new method for estimating the angular difference between two tomographic projections belonging to a set of projections taken at unknown directions in 2D and 3D. Our method relies on the projection neighbor selection in projection moment space, the calculation of the angular differences between these neighboring projections using moment properties and a projection moment neighborhood graph. The accuracy and the robustness of our method are shown on a test database including fifty 2D and 3D gray-level images at different resolutions and with different levels of noise. 相似文献
65.
Yoen-Ju Son 《Drug development and industrial pharmacy》2013,39(9):948-959
The dry powder inhaler (DPI) has become widely known as a very attractive platform for drug delivery. Many patients have traditionally used DPIs to treat asthma and chronic obstructive pulmonary disease. Recently, the development of new DPIs for delivering therapeutic proteins such as insulin has been accelerated by patient demands, and innovative research. The current market for DPIs has over 20 devices presently in use, and many devices under development for delivering a variety of therapeutic agents. DPIs are recognized as suitable alternatives to pressurized metered dose inhalers for some patients, but the performance of DPI devices may vary according to a given patient's physiological condition. This variation can be associated with the necessary powder dispersion mechanism of each device. As such, much interest has focused on the development of efficient powder dispersion mechanisms, as this effectively minimizes the influence of interpatient variability. This article reviews DPI devices currently available, advantages of newly developed devices, outlines some requirements for future device design. 相似文献
66.
Kiho Bae Kyung Sik Son Jun Woo Kim Suk Won Park Jihwan An Fritz B. Prinz Joon Hyung Shim 《International Journal of Hydrogen Energy》2014
This work elucidated the proton-incorporation mechanism in ALD YSZ1. Isotope 2H2O was used as an oxidant to trace proton incorporation. The ratio of ZrO2 to Y2O3 ALD cycles was varied from 1:1 to 5:1. TEM confirmed that the ALD YSZ films grew as fully crystallized columnar grains in the cubic ZrO2 phase. SIMS indicated that the Y3+ and 2H+ concentrations were linearly correlated, indicating yttria-deposition-induced proton incorporation. XPS confirmed an appreciable amount of Y(OH)3 proportional to the 2H+ content in the ALD YSZ, as was also detected by SIMS. Oxide ion vacancies created by the replacement of ZrO2 with relatively small amounts of Y2O3 provided additional vacancies for proton incorporation, resulting in steeper [2H+]/[Y3+] slopes. 相似文献
67.
So Gun-Baek Yi Hyun-Sik Son Yung-Deug Jin Gang-Gyoo 《International Journal of Control, Automation and Systems》2018,16(6):3047-3054
International Journal of Control, Automation and Systems - This paper presents two nonlinear PID (NPID) controllers which control the glycol temperature of a regasification system for LNG-fuelled... 相似文献
68.
Dae Chul Ha Ha Young Lee Yeo Won Son Soon Hong Yuk Youn Woong Choi Byung Kook Kwak Byung Cheol Shin Cheong-Weon Cho Sun Hang Cho 《Nanoscale research letters》2014,9(1):38
The purpose of this study was to synthesize biocompatible poly(2-hydroxyethyl aspartamide)–C16-iron oxide (PHEA-C16-iron oxide) nanoparticles and to evaluate their efficacy as a contrast agent for magnetic resonance imaging of lymph nodes. The PHEA-C16-iron oxide nanoparticles were synthesized by coprecipitation method. The core size of the PHEA-C16-iron oxide nanoparticles was about 5 to 7 nm, and the overall size of the nanoparticles was around 20, 60, and 150 nm in aqueous solution. The size of the nanoparticles was controlled by the amount of C16. The 3.0-T MRI signal intensity of a rabbit lymph node was effectively reduced after intravenous administration of PHEA-C16-iron oxide with the size of 20 nm. The in vitro and in vivo toxicity tests revealed the high biocompatibility of PHEA-C16-iron oxide nanoparticles. Therefore, PHEA-C16-iron oxide nanoparticles with 20-nm size can be potentially useful as T2-weighted MR imaging contrast agents for the detection of lymph nodes. 相似文献
69.
Thin films of NiO were deposited on Pt/Ta/glass sub-strates using a radio frequency (RF) sputtering method. The NiO thin films showed polycrystalline nature, indicating preferentially (111)-oriented structure. The resistive random access memory (RRAM) capacitor of a Pt/NiO/Pt structure exhibited unipolar switching characteristics and bistable resistivities for 200 repeated switching cycles. Furthermore, RRAM nanobits array was formed on the NiO thin films by applying a bias. The RRAM nanobits had a diameter of approximately 8 nm and were observed via a conducting atomic force microscope (CAFM). The density of the RRAM nanobits array was estimated to be approximately 0.64 Tbit/cm2. 相似文献
70.
So Young Kim Cheol Park Min Yeong Kim Seon Yeong Ji Hyun Hwangbo Hyesook Lee Su Hyun Hong Min Ho Han Jin-Woo Jeong Gi-Young Kim Chang-Gue Son JaeHun Cheong Yung Hyun Choi 《International journal of molecular sciences》2021,22(9)
Coptidis Rhizoma is the dried rhizome from the Coptis chinensis Franch. that has been shown to have a number of beneficial pharmacological properties including antioxidant, anti-inflammatory, and anti-cancer effects. However, the anti-cancer effects of Coptidis Rhizoma on hepatocellular carcinoma (HCC) remain unclear. In this study, we investigated the anti-cancer properties of Coptidis Rhizoma ethanol extract (CR) in HCC Hep3B cells and in a xenograft mouse model. Our results showed that the CR significantly inhibited cell growth and induced apoptosis in Hep3B cells through increased expression of Bcl-2 associated x-protein (Bax) and cleavage of poly-ADP ribose polymerase (PARP), reduced expression of Bcl-2, and activated caspases. CR also increased the generation of intracellular reactive oxygen species (ROS), which caused a loss of mitochondrial membrane potential (MMP, ΔΨm) and activation of the mitochondria-mediated intrinsic apoptosis pathway. Moreover, N-acetylcysteine (NAC), a ROS inhibitor, markedly blocked the effects of CR on apoptotic pathways. CR also induced the expression of light chain 3 (LC3)-I/II, a key autophagy regulator, whereas CR-mediated autophagy was significantly suppressed by NAC. In addition, pre-treatment with NAC perfectly attenuated the inhibition of cell invasion and migration of CR-stimulated Hep3B cells. Furthermore, oral administration of CR suppressed Hep3B tumor growth in xenograft mice without toxicity, alterations to body weight, or changes in hematological and biochemical profiles. Taken together, our findings suggest that CR has anti-tumor effects that result from ROS generation, and may be a potential pharmacological intervention for HCC. 相似文献