A genetic algorithm for multiple molecular sequence alignment

MOTIVATION: Multiple molecular sequence alignment is among the most important and most challenging tasks in computational biology. The currently used alignment techniques are characterized by great computational complexity, which prevents their wider use. This research is aimed at developing a new technique for efficient multiple sequence alignment. APPROACH: The new method is based on genetic algorithms. Genetic algorithms are stochastic approaches for efficient and robust searching. By converting biomolecular sequence alignment into a problem of searching for optimal or near-optimal points in an 'alignment space', a genetic algorithm can be used to find good alignments very efficiently. RESULTS: Experiments on real data sets have shown that the average computing time of this technique may be two or three orders lower than that of a technique based on pairwise dynamic programming, while the alignment qualities are very similar. AVAILABILITY: A C program on UNIX has been written to implement the technique. It is available on request from the authors.     

Design of optimum signals for the simultaneous estimation of timedelay and Doppler shift

The problem of joint estimation of time delay and Doppler shift is considered from the point of view of the Wigner distribution of the signal. A very efficient method of obtaining the optimum signal with minimum estimation error based on the convexity of the design region is developed. Practical applications, however, require the signal to satisfy other constraints which present complications in acquiring the optimum signal. A design approach based on the method of simulated annealing is suggested to solve for the optimum signal under constraints. The performance of the signals so obtained is evaluated and compared with that of signals obtained by synthesis     

能消除RGB差分视频传输线上共模噪声的放大器

5类网络电缆由四对双绞线组成,并有耐用的外套,这种电缆能为分量视频信号的传输提供一种通用而有良好性价比的选择。三个线对可以承载RGB视频信号,而第四对线可以承载音频信号、同步信号和其它传输信号。不幸的是,5类电缆缺乏屏蔽,因此容易遭受共模噪声耦合     

Data mining of resilience indicators

In recent years, the Asia-Pacific region has experienced several financial setbacks, including speculative attacks in 1998 and the SARS outbreak in 2003. Financial stresses of this nature are unanticipated, and not all of the dangers can be predicted by the examination of market information and macroeconomic indicators. The Early Warning System (EWS) that has been adopted by the International Monetary Fund may not be able to predict future financial crises for all possible scenarios, because shocks come in many different forms. To supplement the EWS, this paper proposes a data mining framework to measure the resilience of an economy. The resilience framework does not predict a crisis, but rather assesses the current state of health of an economy and its ability to withstand a financial shock should one occur. The framework is based on a feedback system consisting of two stages. The first stage assigns a resilience score to each economy based on a fuzzy logic scoring scheme that is built on the ambiguous reasoning of experts. The second stage uses the classification tree approach to estimate thresholds for each economic indicator, and examines the quality of the fuzzy score. The result from the second stage is then passed back to the first stage as feedback. The final result is obtained when the feedback system reaches its equilibrium state. The proposed resilience framework is applied to the external-sector and the public-sector economies of several countries to illustrate its applicability.     

A broadband PHEMT MMIC distributed doubler using high-pass drain line topology

A broadband frequency doubler, based on distributed amplifier techniques, has been designed to operate from 11 to 21 GHz. In order to reject the fundamental signal over a broadband frequency range, the conventional low-pass drain line structure was replaced with the high-pass structure. This topology can suppress fundamental signals over broadband without any balanced structure so that the chip size can be more compact. Measured conversion losses of better than 10 dB from 11 to 21 GHz input frequencies are achieved with fundamental signal rejection better than 12 dB. To the best of our knowledge, this is the first demonstration of distributed doubler using the high-pass drain line topology.     

WLAN chip antenna mountable above the system ground plane of a mobile device

A novel wireless local-area network (WLAN) chip antenna suitable to be mounted above the system ground plane of a mobile device is presented. The antenna in the study is easily fabricated from folding a single metal plate onto a foam base, and mainly comprises a short-circuited radiating strip and an antenna ground. The antenna ground occupies the bottom surface and two adjacent side surfaces of the foam base. When the antenna is mounted at the corner of the system ground plane, this antenna ground structure is expected to effectively reduce the antenna's possible fringing electromagnetic fields inside the mobile device. In this case, when the associated element such as the radio-frequency shielding metal case is placed under the proposed antenna, small or negligible variations in the antenna performance are obtained. Design considerations of the proposed antenna for WLAN operation in the 2.4 GHz band are described, and results of the constructed prototypes are presented.     

Surface-mount dual-loop antenna for 2.4/5 GHz WLAN operation

A surface-mount dual-loop antenna suitable for dual-frequency WLAN operation is presented. For achieving dual-frequency operation with a compact size, the antenna comprises two loop strips of different sizes printed on a flexible printed circuit board, which is then bent and attached onto a foam base of compact size. The antenna shows an attractive feature of high antenna gain, about 4 and 5 dBi for frequencies across the 2.4 and 5 GHz WLAN bands, respectively.     

Hydrogenated amorphous silicon thin-film transistor arrays fabricated by digital lithography

A jet-printed digital-lithographic method, in place of conventional photolithography, was used to fabricate 64 /spl times/ 64 pixel (300 /spl mu/m pitch) matrix addressing thin-film transistor (TFT) arrays. The average hydrogenated amorphous silicon TFT device within an array had a threshold voltage of /spl sim/3.5 V, carrier mobility of 0.7 cm/sup 2//V/spl middot/s, subthreshold slope of 0.76 V/decade, and an on/off ratio of 10/sup 8/.     

On teletraffic applications to OBS

We provide teletraffic models for loss probability evaluation of optical burst switching (OBS). We show that the popular Engset formula is not exact for OBS modeling and demonstrate that in certain cases it is not appropriate. A new exact model is provided. The various models are compared using numerical results for various OBS alternatives with and without burst segmentation.