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排序方式: 共有625条查询结果,搜索用时 15 毫秒
21.
Xu Xuan Khoshima Sina Karajic Milana Balderman Jan Markovic Katarina Scancar Janez Samardzija Zoran Sturm Saso Rozman Kristina Zuzek 《Journal of Applied Electrochemistry》2022,52(7):1081-1090
Journal of Applied Electrochemistry - The consumption of critical raw materials, especially those in permanent magnets of Nd–Fe–B and Sm–Co-type, has significantly grown in the... 相似文献
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Tatiana B. Eronina Valeriya V. Mikhaylova Natalia A. Chebotareva Kristina V. Tugaeva Boris I. Kurganov 《International journal of molecular sciences》2022,23(7)
Protein–protein interactions (PPIs) play an important role in many biological processes in a living cell. Among them chaperone–client interactions are the most important. In this work PPIs of αB-crystallin and glycogen phosphorylase b (Phb) in the presence of betaine (Bet) and arginine (Arg) at 48 °C and ionic strength of 0.15 M were studied using methods of dynamic light scattering, differential scanning calorimetry, and analytical ultracentrifugation. It was shown that Bet enhanced, while Arg reduced both the stability of αB-crystallin and its adsorption capacity (AC0) to the target protein at the stage of aggregate growth. Thus, the anti-aggregation activity of αB-crystallin increased in the presence of Bet and decreased under the influence of Arg, which resulted in inhibition or acceleration of Phb aggregation, respectively. Our data show that chemical chaperones can influence the tertiary and quaternary structure of both the target protein and the protein chaperone. The presence of the substrate protein also affects the quaternary structure of αB-crystallin, causing its disassembly. This is inextricably linked to the anti-aggregation activity of αB-crystallin, which in turn affects its PPI with the target protein. Thus, our studies contribute to understanding the mechanism of interaction between chaperones and proteins. 相似文献
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A simulation of the polymerization of methylmethacrylate in a CSTR is adaptively controlled by two types of pole-placement algorithms. The strongly nonlinear polymerization process, exhibiting multiple steady states, presents difficult control problems for conventional feedback controllers. The performance of an adaptive explicit SISO controller and that of an adaptive implicit multivariable controller are compared and evaluated as applied to this process. The plant is identified by a recursive least squares estimator. Modifications made to the estimation algorithm help to maintain adequate closed-loop results. A simple warm-up procedure is introduced that successfully initializes the controller and estimator during plant start-up. Good servo and regulatory control are achieved by both pole-placement schemes. 相似文献
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The U.S. Food Safety and Inspection Service (FSIS) pathogen reduction-hazard analysis critical control point systems final rule, published in 1996, established Salmonella performance standards for broiler chicken, cow and bull, market hog, and steer and heifer carcasses and for ground beef, chicken, and turkey meat. In 1998, the FSIS began testing to verify that establishments are meeting performance standards. Samples are collected in sets in which the number of samples is defined but varies according to product class. A sample set fails when the number of positive Salmonella samples exceeds the maximum number of positive samples allowed under the performance standard. Salmonella sample sets collected at 1,584 establishments from 1998 through 2003 were examined to identify factors associated with failure of one or more sets. Overall, 1,282 (80.9%) of establishments never had failed sets. In establishments that did experience set failure(s), generally the failed sets were collected early in the establishment testing history, with the exception of broiler establishments where failure(s) occurred both early and late in the course of testing. Small establishments were more likely to have experienced a set failure than were large or very small establishments, and broiler establishments were more likely to have failed than were ground beef, market hog, or steer-heifer establishments. Agency response to failed Salmonella sample sets in the form of in-depth verification reviews and related establishment-initiated corrective actions have likely contributed to declines in the number of establishments that failed sets. A focus on food safety measures in small establishments and broiler processing establishments should further reduce the number of sample sets that fail to meet the Salmonella performance standard. 相似文献
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Nader Makki Kristina W. Thiel Francis J. Miller Jr. 《International journal of molecular sciences》2013,14(10):20597-20613
The epidermal growth factor receptor (EGFR) family and its ligands serve as a switchboard for the regulation of multiple cellular processes. While it is clear that EGFR activity is essential for normal cardiac development, its function in the vasculature and its role in cardiovascular disease are only beginning to be elucidated. In the blood vessel, endothelial cells and smooth muscle cells are both a source and a target of EGF-like ligands. Activation of EGFR has been implicated in blood pressure regulation, endothelial dysfunction, neointimal hyperplasia, atherogenesis, and cardiac remodeling. Furthermore, increased circulating EGF-like ligands may mediate accelerated vascular disease associated with chronic inflammation. Although EGFR inhibitors are currently being used clinically for the treatment of cancer, additional studies are necessary to determine whether abrogation of EGFR signaling is a potential strategy for the treatment of cardiovascular disease. 相似文献
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Constraining Si Particles within Graphene Foam Monolith: Interfacial Modification for High‐Performance Li+ Storage and Flexible Integrated Configuration 下载免费PDF全文
Yue Ma Reza Younesi Ruijun Pan Chenjuan Liu Jiefang Zhu Bingqing Wei Kristina Edström 《Advanced functional materials》2016,26(37):6797-6806
Pulverization of electrode materials and loss of electrical contact have been identified as the major causes for the performance deterioration of alloy anodes in Li‐ion batteries. This study presents the hierarchical arrangement of spatially confining silicon nanoparticles (Si NPs) within graphene foam (GF) for alleviating these issues. Through a freeze‐drying method, the highly oriented GF monolith is engineered to fully encapsulate the Si NPs, serving not only as a robust framework with the well‐accessible thoroughfares for electrolyte percolation but also a physical blocking layer to restrain Si from direct exposure to the electrolyte. In return, the pillar effect of Si NPs prevents the graphene sheets from restacking while preserving the highly efficient electron/Li+ transport channels. When evaluated as a binder‐free anode, impressive cycle performance is realized in both half‐cell and full‐cell configurations. Operando X‐ray diffraction and in‐house X‐ray photoelectron spectroscopy confirm the pivotal protection of GF to sheathe the most volume‐expanded lithiated phase (Li15Si4) at room temperature. Furthermore, a free‐standing composite film is developed through readjusting the pore size in GF/Si monolith and directly integrated with nanocellulose membrane (NCM) separator. Because of the good electrical conductivity and structural integrity of the GF monolith as well as the flexibility of the NCM separator, the as‐developed GF/Si‐NCM electrode showcases the potential use in the flexible electronic devices. 相似文献
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Current knowledge of the potential for an increased use of industrial district heating (DH) due to conversions of industrial processes to DH is limited. In this paper, a Method for Heat Load Analysis (MeHLA) for exploring industrial DH conversions has been developed. This method can be a helpful tool for analyzing the impact different industrial processes have on the local DH system, when processes that utilize electricity and other fuels, convert to utilizing DH. Heat loads for different types of industries and processes are analyzed according to characteristics such as temperature levels and time-dependency. MeHLA has been used to analyze 34 Swedish industries and the method demonstrates how conversion of industrial processes to DH can result in heat load duration curves that are less outdoor temperature-dependent and more evenly distributed over the year. An evenly distributed heat load curve can result in increased annual operating time for base load DH plants such as cogeneration plants, leading to increased electricity generation. In addition to the positive effects for the DH load duration curve, the conversions to DH can also lead to an 11% reduction in the use of electricity, a 40% reduction in the use of fossil fuels and a total energy end-use saving of 6% in the studied industries. Converting the industrial processes to DH will also lead to a potential reduction of the global carbon dioxide emissions by 112,000 tonnes per year. 相似文献
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General spousal perceived criticism (PC) robustly predicts psychological symptoms and is associated with marital discord (e.g., Hooley & Teasdale, 1989); however, it is unclear what types of criticism PC encompasses (Renshaw, 2008). One hundred eighteen couples rated general PC and both constructive and destructive criticism from their own videotaped spousal discussions. Independent judges also coded criticism from the discussions. Results suggest that destructive rather than constructive criticism is related to PC. That PC primarily reflects destructive criticism may explain its utility in predicting relapse. Future studies will benefit from separate application of constructive and destructive criticism measures. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
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