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61.
Jiecheng Yang Liliana Bello Kevin Buettner Yu Guo Carl Wassgren Jennifer S. Curtis 《American Institute of Chemical Engineers》2019,65(8):e16626
The breakage of an agglomerate of wet flexible fibers impacting a plane is computationally investigated in this work using the discrete element method. In the agglomerate, the fibers stick together due to cohesive liquid bridge forces. Agglomerate breakage with various impact conditions, initial configurations, fiber properties, and liquid bridge properties is systematically investigated. The degree of breakage is governed by the impact energy, the cohesion energy due to liquid bridges, the energy dissipation/absorption through fiber–fiber contacts and fiber deformation, and the efficiency of force transmission within the agglomerate. More specifically, breakage is promoted by increasing impact velocity, decreasing agglomerate size, increasing initial compaction, increasing fiber bending modulus, decreasing liquid surface tension, and decreasing liquid-to-solid volume ratio. Breakage is strongly dependent on the modified Weber number, that is, the ratio of the Weber number to a dimensionless rupture distance, which is a measure of the impact energy relative to the cohesion energy. 相似文献
62.
Liliana Jimenez Emilio Alarcón Colleen Trevithick-Sutton Niket GandhiJuan C. Scaiano 《Food chemistry》2011
The effect of γ-radiation on green onion DNA integrity, phenol content, oxygen radical absorbance capacity, employing pyrogallol red and fluorescein as probes, as well as ascorbic acid content has been evaluated. Measurements using thiazole orange-DNA fluorescence and agarose gel electrophoresis show that γ-radiation does not lead to an apparent DNA change in green onion. However, it was readily cleaved upon irradiation from the previously isolated nucleic acid. Furthermore, green onion exposure to γ-radiation produces slight increases in the polyphenol concentrations (163–188 μM Trolox eq.) and a decrease in the oxygen radical absorbance using fluorescein (from 245 to 200 Trolox eq.) Interestingly, a high ascorbic acid content (364 μM), which decreases by 40% after γ-ray exposure was measured by using pyrogallol-red-based oxygen radical absorbance capacity induction times from green onion aqueous extracts. Thus, our results suggest that ascorbic acid present in green onion plays a fundamental role in the plant antioxidant response toward γ-radiation exposure, while polyphenols remain largely unchanged, as revealed from oxygen radical absorbance capacity, employing pyrogallol red. 相似文献
63.
Osvaldo Da Pos Dhanraj Vishwanath Liliana Albertazzi 《Color research and application》2021,46(1):88-102
Although color plays a crucial role in the demarcation of surfaces in the visual field, its role in depth perception is not well understood. Certain special effects of color on depth perception that arise from optical factors such as chromatic aberration (chromostereopsis) have been studied, but less is known about the role of perceptual factors of color in determining depth relations. The present study explores the role that the different attributes of color such as hue, chroma, and lightness play in the stratification of surfaces in depth. In two experiments, subjects manipulated specific dimensions of colors (hue, chroma, lightness, and whiteness) while making judgments of coplanarity of either two or more abutting surfaces. The results demonstrate that for surfaces to appear coplanar, their lightness has to be proportional to the natural (intrinsic) lightness of the hues. No meaningful effects of chroma, whiteness, or blackness were found in depth stratification. The results suggest a primary role of the natural lightness of hues in depth perception. 相似文献
64.
Florina D. Cojocaru Vera Balan Constantin-Edi Tanase Ionel Marcel Popa Maria Butnaru Ovidiu Bredetean Mihai Mares Valentin Nastasa Sorin Pasca Liliana Verestiuc 《Ceramics International》2021,47(8):11209-11219
Fine-tuning of the scaffolds structural features for bone tissue engineering can be an efficient approach to regulate the specific response of the osteoblasts. Here, we loaded magnetic nanoparticles aka superparamagnetic iron oxide nanoparticles (SPIONs) into 3D composite scaffolds based on biological macromolecules (chitosan, collagen, hyaluronic acid) and calcium phosphates for potential applications in bone regeneration, using a biomimetic approach. We assessed the effects of organic (chitosan/collagen/hyaluronic acid) and inorganic (calcium phosphates, SPIONs) phase over the final features of the magnetic scaffolds (MS). Mechanical properties, magnetic susceptibility and biological fluids retention are strongly dependent on the final composition of MS and within the recommended range for application in bone regeneration. The MS architecture/pore size can be made bespoken through changes of the final organic/inorganic ratio. The scaffolds undertake mild degradation as the presence of inorganic components hinders the enzyme catalytic activity. In vitro studies indicated that osteoblasts (SaOS-2) on MS9 had similar cell behaviour activity in comparison with the TCP control. In vivo data showed an evident development of integration and resorption of the MS composites with low inflammation activity. Current findings suggest that the combination of SPIONs into 3D composite scaffolds can be a promising toolkit for bone regeneration. 相似文献
65.
Bogdan Obric Bogdan Sorohan Liliana Tu Gener Ismail 《International journal of molecular sciences》2021,22(7)
Systemic lupus erythematosus (SLE) is the prototype of autoimmune disorders caused by a loss of tolerance to endogenous nuclear antigens triggering an aberrant autoimmune response targeting various tissues. Lupus nephritis (LN), a major cause of morbidity and mortality in patients with SLE, affects up to 60% of patients. The recent insights into the genetic and molecular basis of SLE and LN paved the way for newer therapies to be developed for these patients. Apart from the traditional B-cell-centered view of this disease pathogenesis, acknowledging that multiple extrarenal and intrarenal pathways contribute to kidney-specific autoimmunity and injury may help refine the individual therapeutic and prognostic characterization of such patients. Accordingly, the formerly induction-maintenance treatment strategy was recently challenged with the exciting results obtained from the trials that evaluated add-on therapy with voclosporin, belimumab, or Obinutuzumab. The scope of this review is to provide an insight into the current knowledge of LN pathogenesis and future therapeutic strategies. 相似文献
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García-Alcaraz Jorge Luis Montalvo Francisco Javier Flor Avelar-Sosa Liliana Pérez de la Parte María Mercedes Blanco-Fernández Julio Jiménez-Macías Emilio 《Wireless Networks》2020,26(8):5713-5726
Wireless Networks - This paper presents a structural equation model that relates knowledge coordination with access to information in the process of implementing Six Sigma and their impact on the... 相似文献
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