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991.
Self-locking analysis in closed kinematic chains is sometimes likened to kinematic singularity analysis, especially when mechanisms are characterized by more than one degree of freedom. Although in singular configurations a mechanism is obviously locked-up since joint constraint reactions and friction forces rise to infinity, this approach identifies only a condition sufficient for self-locking, while the phenomenon actually occurs in a larger domain, the size of which depends on the values of friction coefficients.The paper proposes a definition of self-locking for multi degrees of freedom mechanisms and presents an algorithm for computing the geometrical locus that corresponds to a specific self-locking configuration. This methodology is then demonstrated on a simple parallel kinematic mechanism with two degrees of freedom. 相似文献
992.
993.
This article focuses on the dynamic index and performance of a radial symmetric six-legged robot. At first the structure of the robot is described in brief and its inverse kinematics is presented. Then the dynamic model is formulated as based on the Lagrange equations. A novel index of total torque is proposed by considering the posture of the supporting legs. The new index can be used to optimize the leg’s structure and operation for consuming minimum power and avoiding unstable postures of the robot. A characterization of the proposed six-legged robot is obtained by a parametric analysis of robot performance through simulation using the presented dynamic model. Main influences are outlined as well as the usefulness of the proposed performance index. 相似文献
994.
This paper presents four calibrations carried out in four different, independent, metrological accredited laboratories, on six diaphragm gas meters for domestic use (G4). The aim of this study is to evaluate the degree of metrological agreement among different calibration results, by means of the assessment of suitable factors (compatibility index, also known as normalized error). This application study is quite interesting in the field of “legal metrology”, when often conformity assessment are requested in order to assure the adequate behavior of a domestic gas meter. The six gas meters were calibrated in four different laboratories, each of them characterized by different values of the calibration uncertainty (also called CMC = Calibration and Measurement Capability, or BMC = Best Measurement Capability, or Minimum Uncertainty). Two alternative approaches about the metrological compatibility are introduced: a quantitative approach and a qualitative approach. The calibration results show that for diaphragm gas meters for domestic use, the metrological agreement should be preferable by means of the qualitative approach. 相似文献
995.
Mass spectrometry in the diagnosis of thyroid disease and in the study of thyroid hormone metabolism
Marco Borsò Patrizia Agretti Riccardo Zucchi Alessandro Saba 《Mass spectrometry reviews》2022,41(3):443-468
The importance of thyroid hormones in the regulation of development, growth, and energy metabolism is well known. Over the last decades, mass spectrometry has been extensively used to investigate thyroid hormone metabolism and to discover and characterize new molecules involved in thyroid hormones production, such as thyrotropin-releasing hormone. In the earlier period, the quantification methods, usually based on gas chromatography–mass spectrometry, were complicated and time consuming. They were mainly focused on basic research, and were not suitable for clinical diagnostics on a routine basis. The development of the modern mass spectrometers, mainly coupled to liquid chromatography, enabled simpler sample preparation procedures, and the accurate quantification of thyroid hormones, of their precursors, and of their metabolites in biological fluids, tissues, and cells became feasible. Nowadays, molecules of physiological and pathological interest can be assayed also for diagnostic purposes on a routine basis, and mass spectrometry is slowly entering the clinical laboratory. This review takes stock of the advancements in the field of thyroid metabolism that were carried out with mass spectrometry, with special focus on the use of this technique for the quantification of molecules involved in thyroid diseases. 相似文献
996.
In this work, the fretting behaviour of pure Ti plates laser treated with a Nd:YAG pulsed laser was compared to that of untreated Ti plates. Fretting tests were done at room temperature without lubrication. The contact geometry was a cylinder (bearing steel) on a plane. The evolution of both the ratio, μ=Q/P, between the normal and the tangential forces, and the Fouvry's energy criterion (A) were recorded as a function of the number of fretting cycles, N. Energy dispersive spectrometry and micro-Raman spectroscopy were used to analyse the fretting scars. The oxidized layer formed by the laser treatment displayed a mixed slip regime as a function of N, and a smaller fretting coefficient μ than the titanium reference. 相似文献
997.
Pedersoli E Capotondi F Cocco D Zangrando M Kaulich B Menk RH Locatelli A Mentes TO Spezzani C Sandrin G Bacescu DM Kiskinova M Bajt S Barthelmess M Barty A Schulz J Gumprecht L Chapman HN Nelson AJ Frank M Pivovaroff MJ Woods BW Bogan MJ Hajdu J 《The Review of scientific instruments》2011,82(4):043711
We present a compact modular apparatus with a flexible design that will be operated at the DiProI beamline of the Fermi@Elettra free electron laser (FEL) for performing static and time-resolved coherent diffraction imaging experiments, taking advantage of the full coherence and variable polarization of the short seeded FEL pulses. The apparatus has been assembled and the potential of the experimental setup is demonstrated by commissioning tests with coherent synchrotron radiation. This multipurpose experimental station will be open to general users after installation at the Fermi@Elettra free electron laser in 2011. 相似文献
998.
999.
1000.
Marco Leonesio Paolo Parenti Alberto Cassinari Giacomo Bianchi 《The International Journal of Advanced Manufacturing Technology》2014,72(9-12):1347-1360
In this paper, a particular kind of non-regenerative instability in surface grinding is studied. Clear evidences have been collected suggesting that vibrations can occur suddenly even during the first grinding pass, just after wheel dressing. These circumstances exclude workpiece and wheel surface regeneration as instability origin, whereas both surfaces have to be considered initially smooth. On these bases, the stability of the dynamic system constituted by an oscillating ideal wheel (namely without waviness on the surface) immerged in a positional and velocity-dependent process force field has been studied, demonstrating that, under particular conditions, the force field generates an unstable behaviour. The instability occurrence is strictly related to the oscillation direction of the wheel centre, according to the mode shape associated to the dominant resonance, with respect to the direction of the grinding force (identified by the ratio between its tangential and normal components). The analysis leads to the identification of a simple necessary condition for instability occurrence. The analytical results are confirmed by time-domain grinding simulations and compared with experimental evidences. 相似文献