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排序方式: 共有2687条查询结果,搜索用时 15 毫秒
71.
研究辊速差对连铸连轧7075铝板显微组织、织构及力学性能的影响.采用3种不同上辊/下辊转速比(ω/ω0,ω为上辊转速,ω0为下辊转速)1:1、1:1.2及1:1.4进行多次试验.结果显示,在最大辊速差条件下(ω/ω0=1:1.4),7075铝板在轧制方向的屈服强度和极限抗拉强度分别提高41.5%和21.9%.此外,当辊... 相似文献
72.
Since the discovery of camelid heavy-chain antibodies in 1993, there has been tremendous excitement for these antibody domains (VHHs/sdAbs/nanobodies) as research tools, diagnostics, and therapeutics. Commercially, several patents were granted to pioneering research groups in Belgium and the Netherlands between 1996–2001. Ablynx was established in 2001 with the aim of exploring the therapeutic applications and development of nanobody drugs. Extensive efforts over two decades at Ablynx led to the first approved nanobody drug, caplacizumab (Cablivi) by the EMA and FDA (2018–2019) for the treatment of rare blood clotting disorders in adults with acquired thrombotic thrombocytopenic purpura (TPP). The relatively long development time between camelid sdAb discovery and their entry into the market reflects the novelty of the approach, together with intellectual property restrictions and freedom-to-operate issues. The approval of the first sdAb drug, together with the expiration of key patents, may open a new horizon for the emergence of camelid sdAbs as mainstream biotherapeutics in the years to come. It remains to be seen if nanobody-based drugs will be cheaper than traditional antibodies. In this review, I provide critical perspectives on camelid sdAbs and present the promises and challenges to their widespread adoption as diagnostic and therapeutic agents. 相似文献
73.
Mehdi Bezahaf Luigi Iannone Marcelo Dias de Amorim Serge Fdida 《Computer Networks》2012,56(5):1568-1583
Over the latest few years, cross-layer design in wireless networks has drawn great attention from the research community. One of the main arguments in favor of such techniques is that the hop-count metric alone is not enough to capture the specificities of wireless links (e.g., interferences, collisions, fading). In this paper, we address a simple yet fundamental question: What are the real improvements that cross-layering can bring to routing performance when compared to the simple hop-count metric? In our experiments, we consider the backbone of a real wireless mesh network composed of 12 routers deployed in an office building. We focus on the stability of routes and their persistence. In spite of the nature of cross-layer metrics that take into account information from different layers, lets them be very reactive to changes, we observe that using these metrics, pairs of nodes tend to mainly use the same set of two or three routes between them. 相似文献
74.
Fluid flow through the gas diffusion layer (GDL) of fuel cells is numerically studied using a pore network modeling approach. The model is developed based on an experimental visualization technique (fluorescence microscopy). The images obtained from this technique are analyzed to find patterns of flow inside the GDL samples with different hydrophobicity. Three different flow patterns are observed: initial invasion, progression, and pore-filling. The observation shows that liquid water flows into the majority of available pores on the boundary of the untreated GDL and several branches are segregated from the initial pathways. For the treated GDL, however, a handful of boundary pores are invaded and the original pathways extend toward the other side of the medium with minimum branching. The numerical model, developed based on an invasion percolation algorithm, is used to study the effects of GDL hydrophobicity and thickness on the flow configuration and breakthrough time as well as to determine the flow rate and saturation in different GDL samples. During the injection of water into the samples, it is numerically shown that the flow rates are monotonically decreasing for both treated and untreated samples. For the treated sample, however, the injection flow rate is constantly lower than that of the untreated sample, resulting in a lower overall water saturation at breakthrough. The numerical results also suggest that hydrophobic treatment of thick samples has minor effects on water management and overall performance. The developed model can be used to optimize the GDL properties for designing porous medium with effective transport characteristics. 相似文献
75.
Two new optical single side band (OSSB) configurations for radio frequency (RF) transmission of data are proposed based on the structures that have been designed for baseband digital data transmission. The performances of these schemes are evaluated based on the relevant eye diagrams and bit error rate (BER). The proposed configurations are studied and analyzed mathematically. Eye diagrams and BER’s indicate an acceptable performance for the suggested structures. Feasible settings for the RF electrical power of the links are considered and the link performance for each setting is evaluated. A 4-dense wavelength division multiplexing (4-DWDM) link is considered for transmitting different types of data over a single mode fiber (SMF). Baseband digital data in the format of OSSB and RF-OSSB signals are transmitted over a 4-DWDM link. Furthermore, the link performance is considered for different electrical power settings of OSSB signal in order to achieve efficient transmission for DWDM network. 相似文献
76.
In this paper, a laminated composite plate is analyzed using a multiscale method. At first, material properties of a lamina are obtained using an analytical micromechanical approach called simplified unit cell method (SUCM), and then in structural level, the generalized differential quadrature method (GDQM) is used to analyze a laminated composite plate. By means of the Boltzmann superposition principle, the viscoelastic behavior of the matrix is obtained. The Prony series is considered to define the compliance of matrix. To verify the results, graphiteT300/epoxy5208 composite material is analyzed and the results are compared with existing experimental data. The multiscale algorithm includes obtaining overall properties of the composite by SUCM; then, these properties are used to define the bending stiffness. Governing equations of motion of laminated composite plate are solved via GDQM and Newton–Raphson method. Variations of stresses and displacements versus time and volume fraction of the fibers are shown for laminated composite plates with different boundary conditions. 相似文献
77.
Masoud Rakhshani Mohammad Mehdi Kamrannejad Ali Akbar Babaluo Mostafa Rezaei Mirkarim Razavi Aghjeh 《Iranian Polymer Journal》2012,21(12):821-828
Polyacrylamide gel (PAMG) method is a simple, fast and cheap method used for the synthesis of a wide variety of nanopowders. However, no adequate results have been reported on the thermal degradation behavior of PAMG which can be very effective on the final product properties. In this work, thermal degradation behavior of PAMG in the presence of TiCl4 as a precursor salt for synthesis of TiO2 nanoparticles was examined in comparison with linear polyacrylamide (LPAM) and pure PAMG by thermogravimetry/differential thermal analysis. Their thermal degradation kinetics was investigated, as well. The results showed that thermal degradation of all samples occurred in two stages at different onset temperatures. Despite the high thermal stability of pure PAMG compared to LPAM, the presence of TiCl4 as a mineral material in PAMG structure decreases the thermal degradation onset temperature, considerably. Furthermore for LPAM and PAMG, majority of weight loss occurs in the second stage, but in PAMG with TiCl4 the weight loss occurs mainly at the first stage. For more detailed investigation, residual materials were characterized by Fourier transform infrared spectroscopy and X-ray diffraction (XRD) techniques, attributing this trend to the presence of mineral materials in PAMG structure. XRD and transmission electron microscopy were also applied to confirm anatase crystalline structure and nanoscale distribution of the TiO2 particles synthesized via PAMG method. 相似文献
78.
Mehdi Taassori Meysam Taassori Sener Uysal 《Design Automation for Embedded Systems》2016,20(3):191-210
Network on chip (NoC) has been proposed as an appropriate solution for today’s on-chip communication challenges. Power dissipation has become a key factor in the NoCs because of their shrinking sizes. In this paper, we propose a new encoding approach aimed at power reduction by decreasing the number of switching activities on the buses. This approach assigns the symbols to data word in such a way that the more frequent words are sent by less power consumption. This algorithm dedicates the symbols with less ones to high probability data and uses transition signaling to transmit data. The proposed method, unlike the existing low power encoding, does not rely on spatial redundancy and keeps the width of the bus constant. Experimental evaluations show that our approach reduces the power dissipation up to 46 % with 2.70, 0.51, and 15.43 % power, critical path and area overhead in the NoCs, respectively. 相似文献
79.
80.
In the modeling of brain mechanics subjected to primary blast waves, there is currently no consensus on how many biological components to be used in the brain–meninges–skull complex, and what type of constitutive models to be adopted. The objective of this study is to determine the role of layered meninges in damping the dynamic response of the brain under primary blast loadings. A composite structures composed of eight solid relevant layers (including the pia, cerebrospinal fluid (CSF), dura maters) with different mechanical properties are constructed to mimic the heterogeneous human head. A hyper-viscoelastic material model is developed to better represent the mechanical response of the brain tissue over a large strain/high frequency range applicable for blast scenarios. The effect of meninges on the brain response is examined. Results show that heterogeneous composite structures of the head have a major influence on the intracranial pressure, maximum shear stress, and maximum principal strain in the brain, which is associated with traumatic brain injuries. The meninges serving as protective layers are revealed by mitigating the dynamic response of the brain. In addition, appreciable changes of the pressure and maximum shear stress are observed on the material interfaces between layers of tissues. This may be attributed to the alternation of shock wave speed caused by the impedance mismatch. 相似文献