Poly (hydroxyethyl methacrylate-glycidyl methacrylate) films modified with different functional groups: In vitro interactions with platelets and rat stem cells

Copolymerization of 2-hydroxyethylmethacrylate (HEMA) with glycidylmethacrylate (GMA) in the presence of α-α′-azoisobisbutyronitrile (AIBN) resulted in the formation of hydrogel films carrying reactive epoxy groups. Thirteen kinds of different molecules with pendant NH₂ group were used for modifications of the p(HEMA-GMA) films. The NH₂ group served as anchor binding site for immobilization of functional groups on the hydrogel film via direct epoxy ring opening reaction. The modified hydrogel films were characterized by FTIR, and contact angle studies. In addition, mechanical properties of the hydrogel films were studied, and modified hydrogel films showed improved mechanical properties compared with the non-modified film, but they are less elastic than the non-modified film. The biological activities of these films such as platelet adhesion, red blood cells hemolysis, and swelling behavior were studied. The effect of modified hydrogel films, including NH₂, (using different aliphatic CH₂ chain lengths) CH₃, SO₃H, aromatic groups with substituted OH and COOH groups, and amino acids were also investigated on the adhesion, morphology and survival of rat mesenchymal stem cells (MSCs). The MTT colorimetric assay reveals that the p(HEMA-GMA)-GA-AB, p(HEMA-GMA)-GA-Phe, p(HEMA-GMA)-GA-Trp, p(HEMA-GMA)-GA-Glu formulations have an excellent biocompatibility to promote the cell adhesion and growth. We anticipate that the fabricated p(HEMA-GMA) based hydrogel films with controllable surface chemistry and good stable swelling ratio may find extensive applications in future development of tissue engineering scaffold materials, and in various biotechnological areas.     

Recovery of phenolic compounds from peach pomace using conventional solvent extraction and different emerging techniques

The study compared high-pressure, microwave, ultrasonic, and traditional extraction techniques. The following extraction conditions were implemented: microwave-assisted extraction (MAE) at 900 W power for durations of 30, 60, and 90 s; ultrasonic-assisted extraction (UAE) at 100% amplitude for periods of 5, 10, and 15 min; and high-pressure processing (HPP) at pressures of 400 and 500 MPa for durations of 1, 5, and 10 min. The highest yield in terms of total phenolic content (PC) was obtained in UAE with a value of 45.13 ± 1.09 mg gallic acid equivalent (GAE)/100 g fresh weight (FW). The highest PC content was determined using HPP-500 MPa for 10 min, resulting in 40 mg GAE/100 g, and MAE for 90 s, yielding 34.40 mg GAE/100 g FW. The highest value of antioxidant activity (AA) was obtained by UAE in 51.9% ± 0.71%. The PCs were identified through the utilization of Fourier transform infrared (FTIR) spectroscopy and high-performance liquid chromatography (HPLC). Utilizing multivariate analysis, the construction of chemometric models were executed to predict AA or total PC of the extracts, leveraging the information from IR spectra. The FTIR spectrum revealed bands associated with apigenin, and the application of HPP resulted in concentrations of 5.41 ± 0.25 mg/100 g FW for apigenin and 1.30 ± 0.15 mg/100 g FW for protocatechuic acid. Furthermore, HPLC analysis detected the presence of protocatechuic acid, caffeic acid, p-coumaric acid, and apigenin in both green extraction methods and the classical method. Apigenin emerged as the predominant phenolic compound in peach extracts. The highest concentrations of apigenin, p-coumaric acid, and protocatechuic acid were observed under HPP treatment, measuring 5.41 ± 0.25, 0.21 ± 0.04, and 1.30 ± 0.15 mg/kg FW, respectively.     

Effect of High-Temperature Treatment on the Mechanical Properties of Rowan (Sorbus aucuparia L.) Wood

Heat treatment is a wood modification method that has been used to some extent in improving timber quality. The high temperature thermal treatment of wood is an environmentally friendly method for wood preservation. This technique has attracted considerable attention both in Europe and in North America in recent years.

This article presents the results of experimental studies on influence of heat treatment on the mechanical properties of Rowan (Sorbus aucuparia L.) wood performed in order to understand its role in wood processing. Samples were exposed to temperature levels of 120, 150, and 180°C for time spans ranging from 2 to 10 h. Mechanical properties including compression strength, modulus of elasticity, modulus of rupture, Janka hardness, impact bending strength, tension strength perpendicular to grain, tension strength parallel to grain, shear strength, and cleavage strength of heat-treated samples were determined. Maximum reduction values of 34.12, 28.40, and 26.37% were found for impact bending strength, tension strength parallel to grain, and cleavage strength for the samples exposed to 180°C for 10 h, respectively. Overall, the results showed that treated samples had lower mechanical properties than those of the control samples. Statistically significant difference was determined (P = 0.05) between mechanical properties of the control samples and those treated at 180°C for 10 h.     

Optimization of Residual Stresses in the Surface Regions of Injection Moldings

The present study focused on the optimization of the injection molding process parameters to minimize thermal residual stresses in the surface regions of the polystyrene and high density polyethylene parts. Process parameters such as melt temperature, mold temperature and cooling time were considered as variables and their effects on residual stresses in surface regions of the parts were investigated by utilizing design of experiment (DOE), Taguchi and analysis of variance (ANOVA) methods. As a result, the most important parameters for residual stresses in surface regions of the PS and HDPE parts were found melt temperature and mold temperature, respectively.     

Outage Probability Analysis of Dual-Hop Decode-and-Forward Relaying Over Mixed Rayleigh and Generalized Gamma Fading Channels

In this letter, outage probability of dual-hop decode-and-forward (DF) relaying scheme is analyzed over mixed Rayleigh and generalized Gamma fading channels. Cooperation model considered in this work consists of a source, a relay and a destination. It is assumed that source-relay and relay-destination channels experience Rayleigh fading and generalized Gamma fading, respectively. Exact outage probability expression is derived and outage performance is illustrated for both direct transmission and DF relaying scheme.     

Synthesis of Chiral N‐Sulfonyl and N‐Phosphinoyl α‐Halo Aldimine Precursors

α‐Halogenated aldimines have emerged as an important class of synthetic intermediates. The stability and reactivity of α‐halo aldimines can vary greatly depending on the nitrogen protecting group. A general synthesis of stable, chiral α‐halo‐N‐sulfonyl and N‐phosphinoyl aldimine precursors is presented (42–96% yield). The corresponding α‐halo aldimines can be isolated upon treatment with a mild base. Enantioenriched α‐chloro aldehydes can be employed to afford aldimine precursors with no erosion of optical purity. Both the enantioenriched aldimine precursor and the isolated aldimine can react with an alkynyllithium nucleophile to give trans‐β‐chloroamine products with excellent dr. Ring closure affords the enantioenriched trans‐aziridine, demonstrating the potential for this approach in complex molecule synthesis.     

Investigation of water absorption performance of polyester-woven fabrics coated with super absorbent polymer

Superabsorbent polymers (SAPs) constitute a special class of polymers widely used in various fields, especially in the hygiene and healthcare sectors. This study investigates the feasibility of achieving high water absorption capacity surfaces by coating powdered SAP using conventional coating methods onto textile surfaces. For this purpose, water-based coating pastes containing micronized SAP powder based on acrylamide/acrylic acid copolymer were coated onto polyester (PES)-woven fabric surfaces using a knife-over-roll coating technique. As the working parameters, the pH value of the coating paste, the coating thickness (the distance between the cloth and the knife), the drying/fixing temperature and time, the SAP concentration, and the water absorption capacity according to time were investigated. The results were evaluated by applying the coating thickness, the amount of coating material transferred to the fabric on the SAP-coated samples, water absorbing capacity, and centrifugal water retention tests. The obtained results have demonstrated that textile surfaces with high water absorption capacity (on average 200%–350%) can be achieved by coating hydrophobic fabric surfaces, such as PES, with SAP under suitable conditions.     

Optimum design of cellular beams using harmony search and particle swarm optimizers

Cellular beams became increasingly popular as an efficient structural form since their introduction. Their sophisticated design and profiling process provide greater flexibility in beam proportioning for strength, depth, size and location of circular holes. The main goal of manufacturing these beams is to increase the moment of inertia and section modulus, which results in greater strength and rigidity. Cellular beams are used as primary or secondary floor beams in order to achieve long spans and service integration. In this study, the design problem of cellular beams is formulated as optimum design problem. The minimum weight is taken as the design objective while the design constraints are implemented from The Steel Construction Institute Publication Number 100. The design methods adopted in this publication are consistent with BS5950 parts 1 and 3. The formulation of the design problem considering the limitations of the above mentioned turns out to be a discrete programming problem. Harmony search and particle swarm optimization methods are used for obtaining the solution of the design problem. The design algorithms based on these two techniques select the optimum UB section to be used in the production of a cellular beam subjected to a general loading, the optimum hole diameter and the optimum number of holes in the cellular beam. Furthermore, this selection is also carried out such that the design limitations are satisfied and the weight of the cellular beam is the minimum. A number of design examples are considered to demonstrate the efficiency of the algorithm presented.     

Empirical formulation for estimating the fundamental frequency of historical stone mosques with masonry domes

Historical stone mosques with masonry dome are complex structures due to their different structural elements, material properties, boundary conditions, connections, etc. It is very difficult to develop the numerical models representing the real behaviour of these structures. Therefore, their numerical models should be checked with ambient vibration tests for the reliable safety evaluations before the restoration applications. However, it is known that the ambient vibration tests of historical mosques are very difficult and costly and need permissions from the owners and relevant government agencies. The paper aims to develop an empirical formulation for estimating the fundamental frequency of historical stone mosques with masonry dome to check the initial finite element models. Nine stone mosques with masonry dome in different dimensions in the eastern Black Sea Region of Turkey were selected as examples for this purpose. By performing ambient vibration tests of the selected mosques, experimental natural frequencies, mode shapes, and damping ratios have been determined and evaluated together. An empirical formulation for the fundamental frequency and coefficients for the second and third frequencies of stone mosques with masonry dome based on vibration data are obtained by using the statistical regression analysis and verified with the control data. The comparative results confirm that the proposed formulation has a reliable predictive performance.     

Characterization of the absorption of histidine and lead by Juglan regia L., Platanus L., and Pinus nigra L. using high-performance liquid chromatography–mass spectrometry and inductively coupled plasma–mass spectrometry

High-performance liquid chromatography–mass spectrometry and inductively coupled plasma – mass spectrometry were used for the determination of histidine and lead in Juglan regia L., Platanus L., and Pinus nigra L. leaves from industrial areas including Gaziantep City and Bursa City, Turkey. Distilled water was used for the extraction of histidine from plant material at 90°C for 30 min. The flow rate of the mobile phase, fragmentation potential, injection volume, and column temperature were optimized to be 0.2 mL min^?1, 70 V, 15 µL, and 20°C for the determination of histidine. The concentrations of histidine were from 7–9 mg kg^?1 for Juglan regia L., 2–5 mg kg^?1 for Platanus L., and 1–7 mg kg^?1 for Pinus nigra L. The concentrations of Pb were from 1–42 mg kg^?1 for Juglan regia L., 1–4 mg kg^?1 for Platanus L., and 1–62 mg kg^?1 for Pinus nigra L.