Inhibition of natural killer cell cytotoxicity by cell growth-related molecules

Certain MHC class I molecules on target cells are known to inhibit the cytotoxic action of NK cells. By using monoclonal antibody (mAb) Cho-1, we have found inhibitory non-MHC class I cell surface molecules that are noncovalently-associated with 200 kDa and 40 kDa antigens. Poly I-C-induced rat NK cells were not cytotoxic to rat fetus-derived fibroblast WFB cell line. In contrast, NK cells were cytotoxic to H-ras oncogene-induced transformants of WFB, W14 and W31. FACS analysis indicated that mAb Cho-1 reacts with WFB, but not with W14 and W31 cells. Thus, this antigen may disappear concomitantly with cell growth and transformation. Cho-1 antigens were also expressed on other NK-resistant lines, such as mouse BALB3T3 fibroblast, EL-4 lymphoma and human fibroblast HEPM. However, they were not expressed on NK-sensitive mouse YAC-1 and H-ras transformant (Brash) of BALB3T3 cells. Furthermore, treatment of target cells with IFN-gamma clearly induced the cell surface expression of Cho-1 antigens, and conferred a resistance to NK cytolysis on target cells. These data strongly suggest that Cho-1 antigen expression may correlate with target cell susceptibility to NK cells. Indeed, treatment of NK-resistant WFB as well as HEPM cells with F(ab')2 fragments of mAb Cho-1 resulted in the acquisition of susceptibility to NK cytolysis. Cho-1 antigens may be novel molecules that regulate the NK resistance of cells.     

高功率激光系统通过空间滤波和中继成像抑制自聚焦

讨论了由光束自聚焦引起的细丝形成和光束分裂，为了克服聚焦造成的破坏要求在光束传播中采用中继成像和空间滤波。     

LD泵浦Nd：YVO4内腔倍频激光器获得120mW绿光连续输出

利用半导体激光器（ＬＤ）端面泵浦Ｎｄ：ＹＶＯ＿４和用ＫＴＰ内腔倍频的绿激光器获得了１２０ｍＷ连续、稳定的５３２ｎｍ绿激光输出。泵浦阈值Ｐ＿（ｔｈ）＝１６０ｍＷ，光－光转换效率η＿ｓ＝８．１％。换用激光腔输出耦合镜，在不加ＫＴＰ晶体倍频时，可连续输出１．０６μｍ的红外激光，输出功率为４５０ｍＷ，光－光转换效率为３１％。     

组合式光纤流量传感器

提出了一种新型的组合式光纤流量传感器，介绍了它的工作原理，详细讨论了光脉冲转换器的设计要点，据此设计了传感头，并给出了它的实验结果。     

Experimental studies of high frequency jet ventilation improved by enhancing expiratory turbulence

A 43-year-old male and a 39-year-old male presented with multiple pituitary adenomas with two distinct histological types. The first patient who had multiple endocrine neoplasia type 1 had developed acromegaly due to a growth hormone-releasing hormone (GHRH)-producing pancreatic tumor. Both plasma GHRH and growth hormone (GH) levels decreased to normal after resection of the pancreatic tumor. However, the plasma GH level gradually increased again and magnetic resonance imaging revealed pituitary adenoma formation. Histological examination revealed two different histological types of pituitary adenoma: GH cell adenoma and null cell adenoma. The second patient, with no such genetic condition, had a non-functioning pituitary adenoma. Histological examination revealed two different histological types of silent GH cell adenoma and silent gonadotroph adenoma. Careful histological examination is required to exclude the possibility of multiple pituitary adenomas.     

厅堂音质的听觉化模拟技术

厅堂音质的听觉化模拟技术是计算机技术、室内声学、电声技术相结合的双耳听觉化模拟技术，是新一代的厅堂音质ＣＡＤ技术的关键。同时听觉化模拟技术也为未来新的立体声制式的出现提供了可能性，这对未来的数字立体声广播、多媒体广播都可能产生巨大的潜在影响。本文对此项技术的原理、声场模拟、听演化实现过程、软件研究及应用前景等作了简要的介绍。     

Computation of 2D discrete Hartley transform

Based on a decimation-in-time decomposition, a fast split-radix algorithm for the 2D discrete Hartley transform is presented. Compared to other reported algorithms, the proposed algorithm achieves substantial savings on the number of operations and provides a wider choice of transform sizes     

宽带被动导引头天线系统性能分析

详细讨论了宽带被动导引头中的关键部件－超宽频带天线的性能，并在此基础上分析了三种具备大视角特性的被动测角方法。由于宽带天线没有确定的相位中心，因此不能采用通常的振幅和差式单脉冲法进行宽频带测角。本文提出的波束运算网络可用于一个宽带螺旋天线同时得到两个交叉波束的振幅－振幅式单脉冲系统中。此外，对比幅相干测向法中的测角模糊问题也进行了研究。     

The PBD-Closure of Constant-Composition Codes

We show an interesting pairwise balanced design (PBD)-closure result for the set of lengths of constant-composition codes whose distance and size meet certain conditions. A consequence of this PBD-closure result is that the size of optimal constant-composition codes can be determined for infinite families of parameter sets from just a single example of an optimal code. As an application, the sizes of several infinite families of optimal constant-composition codes are derived. In particular, the problem of determining the size of optimal constant-composition codes having distance four and weight three is solved for all lengths sufficiently large. This problem was previously unresolved for odd lengths, except for lengths seven and eleven.     

智能同步广播激励器及其标频

使用智能同步广播激励器,并采用CCTV传输的1MHz标频信号,就有可能实现自适应相位跟踪同步广播。这将大大节省中波段的频率资源。