Dietary CLA and DHA modify skin properties in mice

This study investigated the influence of PUFA on the properties of mouse skin. Mice (3 wk old) were given free access to oils high in linoleic acid, CLA, or DHA for 4 wk. At the end of the experiment, their skins were compared by both biochemical and histological methods. No significant differences in lipid and collagen contents were detected among treatments, although the FA composition in the skin was altered depending upon the FA composition of the supplemented oils. Electron microscopy revealed that the subcutaneous tissue layers in the CLA and DHA groups were significantly thinner than that in the high linoleic acid group, whereas no differences in the thickness of dermis layers were observed among the three groups. These results suggest that skin properties in mice are readily modified by dietary FA sources within 4 wk of dietary oil supplementation.     

Polarization state fixer composed of passive optical devices

We investigate a polarization state fixer that produces light with an arbitrary desired polarization state and constant power from an arbitrary elliptically polarized input light whose principal polarization axis fluctuates randomly. An example of such a device composed of a quarter-wave plate and a polarizer is proposed, and its characteristics at wavelengths of 633 nm and 1550 nm are demonstrated. We conclude that we cannot obtain a passive device that produces fixed-axis, linearly polarized light with a constant power level from an elliptically polarized light with a varying elliptical parameter.     

Mask design compensation for sloped sidewall structures fabricated by X-ray lithography

We have investigated and report in this paper the factors influencing the deformation caused by the dependence between the absorbed X-ray energy on the resist and the shape of the absorber on the X-ray mask. Based on the measurement of errors that occurred during the transferring process between the 2-D shape of mask pattern and the resulting wall of the fabricated 3-D structure, we have developed newly useful graphical data on the absorbed X-ray energy, dosage, and shape of a microstructure. As a result, it is being reported as a method for compensation for the deformed shape after the fabrication of a quadruplets-microneedle. We have considered a number of factors affecting the deformation and finally realized that the effect of a dose–depth nonlinear curve is the most possible cause. Without the compensation of the mask design, we could observe the deformed shapes of the sloped sidewall on the exposed structures. Polymethylmethacrylate microneedle structures fabricated by X-ray lithography with an additional plane-pattern to cross-section transfers technique are directly influenced by the absorber on the X-ray mask pattern. The sidewall of the microneedle was improved by changing the mask pattern from a double right-triangular pattern to a double semi-circular pattern, modeled by comparing the results from a mask-pattern and the actual structure.     

10-GHz 8.7-ps Pulse Generation From a Single-Mode Gain-Switched AlGaAs VCSEL at 850 nm

We have successfully generated a 10-GHz 8.7-ps pulse train at 850 nm by using a gain switching technique with a high-speed AlGaAs-based vertical-cavity surface-emitting laser (VCSEL). The VCSEL, which operates in a single transverse mode by employing an aluminum oxide aperture, has a modulation bandwidth of 6.3 GHz and a relaxation oscillation frequency at around 11.7 GHz. An error-free 10-Gb/s return-to-zero data modulation was demonstrated by using the generated 10-GHz pulse train.     

Design and evaluation of robot patient for nursing skill training in patient transfer

We developed a robot patient for patient transfer training for simulating a patient’s performance during patient transfer and for enabling nurses to practice their nursing skills on it. To realize the robot patient, we focused on addressing the problems of designing its limb actions to enable it to respond to nurses’ operations. RC servos and electromagnetic brakes were installed in the joints to enable the robot to simulate a patient’s limb actions, such as embracing and remaining standing. To enable the robot to automatically respond to nurses’ operations, an identification method for these operations was developed that used voice commands and the features of the limbs’ posture measured by angle sensors installed in the robot’s joints. The robot patient’s performance was examined by a control test in which four experienced nursing teachers performed patient transfer with the robot patient and a human-simulated patient. The results revealed that the robot patient could successfully simulate the actions of a patient’s limbs according to the nursing teachers’ operations and that it is suitable for nursing skill training.     

Influence of developer temperature on the shape of structures fabricated by deep X-ray lithography

This paper describes the fabrication of poly(methyl methacrylate) (PMMA) microstructures with three-dimensional (3-D) sloped sidewalls using synchrotron-radiated (SR) deep X-ray lithography (DXRL). Here, the developer temperature was varied to produce variations in the inclination angle of the sloped sidewalls. We found that the PMMA sidewall inclination angle and height were controlled by the dosage, development time, and development temperature. When the development temperature was low, the inclination angle was nearly 0°, regardless of dosage amounts or exposure time. When the development temperature was high, microstructures with sloped sidewalls were fabricated; as the dosage amount and development time increased, the inclination angle increased. The ability to control the PMMA sidewall inclination angle suggests the application of this technique to microstructure fabrication technologies, such as 3-D microelectromechanical system (MEMS) device components, in which the inclination angle becomes the draft angle for moulding processes.     

Design principle of micromechanical probe with an electrostatic actuator for friction force microscopy

It is important to understand friction force in micro/nano mechanical devices both at high sliding speed and with high lateral resolution. Dual-axis friction force microscopes that can provide high lateral resolution and accuracy have been proposed; however, the sliding speed is limited by the probe scan speed. While a micro mechanical probe (MMP) with an electrostatic actuator can overcome this problem, details of probe design have not been established yet. This paper presents the principle of the mechanical design for an MMP with high force sensitivity and sufficient drive force. The dimensions of the double cantilever beam control the spring constants, resonant frequencies, and drive force. The use of an actuated MMP enables accurate friction force microscopy at high sliding speeds, which is required for the design of micro/nano mechanical devices.     

Determination of bisphenol A in canned vegetables and fruit by high performance liquid chromatography

A high performance liquid chromatograph y (HPLC) method was developed for the determination of bisphenol A (BPA) that had migrated into canned fruit and vegetables. BPA was extracted with acetonitrile from the solid portion of canned food, and with an OASIS HLB cartridge from the aqueous portion, respectively. Both extracts were cleaned up on a Florisil cartridge. The HPLC separation was carried out on a Wakosil II 3C18 RS column (4.6 × 150mm) with acetonitrile-water (40:60, v/v) as a mobile phase with a flow rate of 0.8 ml/min. BPA was detectable by UV detector at 228 nm and determined with the similarity of chromatographic peak spectrum by multiwavelength detector (similarity index was 0.99 or above). The quantification limits were 10 ng/g for the solid portion and 5 ng/ml for the aqueous portion, respectively. BPA was mainly detected in the solid portion of canned food and found at the maximum level of 11 μg per can. To verify migration into the solid portion of canned food, a partitioning experiment was carried out.     

Study on environmental effect on fatigue and creep-fatigue strength of 316FR stainless steel in sodium at elevated temperature

Low-carbon 316 stainless steel with medium-nitrogen (316FR) is considered as the principal structural material for next generation fast breeder reactor (FBR) plants in Japan. The material strength standard and the creep-fatigue life evaluation method for 316FR have been developed. However, they are based on the results of material tests in air, while actual structural material will be used mainly in liquid sodium environment in the plants. In order to clarify the environmental effect, cyclic bending tests were carried out with and without hold time in sodium. Tested materials were 316FR and conventional 304 and 316 stainless steels. Weld metal of 316FR was also tested. As a result, it was found that fatigue and creep-fatigue lives of 316FR in sodium were larger than those in air and no explicit consideration of the environmental effect is necessary in design. It was also found that the life evaluation method based on the ductility exhaustion concept is applicable to creep-fatigue life assessment in sodium.     

40 Gbit/s return-to-zero transmission over 500 km of standard fibreusing chirped fibre Bragg gratings with small group delay ripples

A 40 Gbit/s return-to-zero transmission has been successfully achieved over 500 km using standard fibres (non-dispersion shifted fibre, singlemode fibre) and chirped fibre Bragg gratings (CFBG). CFBGs were fabricated with small group delay ripples, and error free transmission (BER <1×10^-12) was achieved using these CFBGs for dispersion compensation