Immunological properties of human decidual macrophages--a possible role in intrauterine immunity

Our aim was to investigate the contribution of decidual macrophages, which constitute an important immune component of the decidua in late gestation, to intrauterine defence mechanisms. Using flow cytometry we examined the ability of decidual macrophages, isolated from term decidua, to bind and phagocytose fluorescence-labelled bacterial and yeast bioparticles. We also assessed their ability to generate superoxide radicals and tumour necrosis factor-alpha following lipopolysaccharide challenge. Decidual macrophages bound bacterial and yeast particles in a dose-dependent manner, which subsequently led to phagocytosis. These macrophages also produced superoxide radicals and the pro-inflammatory cytokine TNF-alpha when challenged with bacterial lipopolysaccharides. These results suggest a role for decidual macrophages in pathogen recognition and clearance during pregnancy, and, therefore, they are likely to protect the fetus against intrauterine infections which might otherwise lead to preterm labour.     

Computed tomography in the postoperative patient

Nine cases of patients in whom intracranial infection was suspected after operation are presented. Lesions with ring enhancement were seen in all of these patients. The differentiation of enhancement, seen as a normal postoperative phenomenon, from residual neoplasia and cerebral abscess can be difficult. This can be resolved by serial and sequential-delayed CT, and thus unnecessary re-exploration may be prevented.     

Quasithermodynamic theory of He3 and He4 solutions

The conventional theory of nonideal solutions is modified on the basis of Gorter's hypothesis, and various properties of He³ and He⁴ solutions are investigated. The variation of -temperature with He³ concentration is explained adequately right up to the phase separation region. A comparison between the theoretical and experimental results for excess chemical potentials, excess entropy, and excess enthalpy is then carried out. In view of the recognized complex behavior of the solution in the region 1 to 2° K, the observed satisfactory agreement between theory and experiment may be regarded as a strong support for the assumptions made in our work.     

Assembly Lines with Overlapping Work Stations

Traditionally assembly line balancing problems have been examined under the assumption of serial work station design. Thus no pair of work stations could be simultaneously working on the same copy of a product. This paper presents two models for which this assumption is dropped. The algorithms developed for operational design of such assembly lines are presented along with sample problems to demonstrate the computational procedures and advantages of these models.     

Response of materials as a function of grinding angle on friction and transfer layer formation

Surface texture influences friction and transfer layer formation during sliding contact. In the present investigation, basic studies were conducted using an inclined pin-on-plate sliding apparatus to understand the effect of grinding mark directionality on the coefficient of friction and transfer layer formation. In the experiments, 080 M40 steel plates were ground to attain different surface roughness with unidirectional grinding marks. Pins consisting of soft materials (pure Al, pure Mg, and Al–4Mg alloy) were then slid against the prepared steel plates. The grinding angle (angle between direction of sliding and grinding marks) was varied between 0° and 90° in the tests. The experiments were conducted under both dry and lubricated conditions in an ambient environment. It was observed that the transfer layer formation and the coefficient of friction depend primarily on the directionality of the plate grinding marks. For the case of pure Mg pins, a stick-slip friction phenomenon was observed for all grinding angles under dry conditions and for grinding angles over 25° under lubricated conditions. In the case of Al pins, the stick-slip phenomenon was observed only under lubricated conditions for angles exceeding 25°. The stick-slip phenomena did not occur in any of the conditions studied with Al–4Mg alloy pins. Based on the results, it was concluded that the magnitudes of the friction and the stick-slip motion amplitude (for Al and Mg pins) were primarily controlled by changes in the level of plowing friction.     

Influence of altitudinal variation on the antioxidant potential of tartar buckwheat of Western Himalaya

In the present work, the effect of altitudinal variations on the total phenol, flavonoid, and antioxidant potential of seeds and hull of Tartar buckwheat collected from 15 different locations of Western Himalaya has been investigated. Methanolic and acetonic extracts of seed and hull powder showed significantly increasing amounts of total polyphenol content, and antioxidant potential with rising altitude. Methanolic extract of seed and hull powder were found to have significantly greater polyphenol, and antioxidant potential as compared to acetonic extract. The methanolic seed extract of Inderdhara (3,133 m) showed the maximum total phenolic content 1,651 μg gallic acid equivalent/50 mg of dry weight. The methanolic seed extract of Inderdhara showed the maximum antioxidant activity (77.29±1.2%) and antiradical activity (55.5±0.5%) also. The results of this study exhibited good correlation with total polyphenol and antioxidant potential in all the samples followed by the increasing tendency towards rising altitude.     

Stability and 2-D Simulation Studies of Avalanche Breakdown in 4H-SiC DMOSFETs With JTE

In this paper, the stability of n-channel 4H-silicon carbide (SiC) DMOSFETs with junction termination extension (JTE) was assessed by measuring the breakdown voltage (BV) of these devices before and after bias stress at a high temperature. The BV slumped after the DMOSFET was bias stressed at 1200 V for 2 h at 175degC, and the slumped BV dynamically recovered to the prestress value during the poststress period. Computer simulation suggests that the BV slump and its recovery are dominated by the positive charge trapping/detrapping phenomena at the SiC/fleld oxide interface in the JTE structure, rather than the trapping/detrapping at the SiC/gate oxide interface in the cell structure. A positive interface charge of approximately one-third of the sheet dopant concentration of the JTE region, lowers BV by 150 V, which is the typical measured BV slump of the DMOSFETs of this paper.     

Performance evaluation of an IEEE 802.15.4 sensor network with a star topology

One class of applications envisaged for the IEEE 802.15.4 LR-WPAN (low data rate—wireless personal area network) standard is wireless sensor networks for monitoring and control applications. In this paper we provide an analytical performance model for a network in which the sensors are at the tips of a star topology, and the sensors need to transmit their measurements to the hub node so that certain objectives for packet delay and packet discard are met. We first carry out a saturation throughput analysis of the system; i.e., it is assumed that each sensor has an infinite backlog of packets and the throughput of the system is sought. After a careful analysis of the CSMA/CA MAC that is employed in the standard, and after making a certain decoupling approximation, we identify an embedded Markov renewal process, whose analysis yields a fixed point equation, from whose solution the saturation throughput can be calculated. We validate our model against ns2 simulations (using an IEEE 802.15.4 module developed by Zheng [14]). We find that with the default back-off parameters the saturation throughput decreases sharply with increasing number of nodes. We use our analytical model to study the problem and we propose alternative back-off parameters that prevent the drop in throughput. We then show how the saturation analysis can be used to obtain an analytical model for the finite arrival rate case. This finite load model captures very well the qualitative behavior of the system, and also provides a good approximation to the packet discard probability, and the throughput. For the default parameters, the finite load throughput is found to first increase and then decrease with increasing load. We find that for typical performance objectives (mean delay and packet discard) the packet discard probability would constrain the system capacity. Finally, we show how to derive a node lifetime analysis using various rates and probabilities obtained from our performance analysis model.