Elimination of beta-blockers in sewage treatment plants

beta-Blockers are used to treat high blood pressure as well as patients recovering from heart attacks. In several studies, they were detected in surface water, thus indicating incomplete degradability of these substances in sewage treatment plants (STPs). In this study, we determined the sorption coefficients (K(D)) and degradation rates of the four beta-blockers sotalol, atenolol, metoprolol and propranolol in sludge from an STP operating with municipal wastewater. The sorption coefficients (K(D), standard deviations in brackets) were determined as 0.04(+/-0.035), 0.04(+/-0.033), 0.00(+/-0.023) and 0.32(+/-0.058) Lg(-1)(COD), and the pseudo-first-order degradation rate constants were estimated to be 0.29(+/-0.02), 0.69(+/-0.05), 0.58(+/-0.05) and 0.39(+/-0.07) Ld(-1)g(-1)(COD) for sotalol, atenolol, metoprolol and propranolol, respectively. These values translate into a typical elimination in STPs (sludge concentrations of 4g(COD)L(-1) and a hydraulic retention time of 6h) of 25%, 37%, 44% and 50% for sotalol, propranolol, metoprolol and atenolol, respectively. These results are also confirmed by measurements in two municipal STPs for atenolol, sotalol and propranolol. The estimated eliminations are slightly too high for metoprolol.     

Indoor air quality in the 21st century: search for excellence

Field studies demonstrate that there are substantial numbers of dissatisfied people in many buildings, among them those suffering from sick building syndrome (SBS) symptoms, even though existing standards and guidelines are met. The reason is that the requirements specified in these standards are rather low, allowing a substantial group of people to become dissatisfied and to be adversely affected. A paradigm shift from rather mediocre to excellent indoor environments is foreseen in the 21st century. Based on existing information and on new research results, five principles are suggested as elements behind a new philosophy of excellence: 1) better indoor air quality increases productivity and decreases SBS symptoms; 2) unnecessary indoor pollution sources should be avoided; 3) the air should be served cool and dry to the occupants; 4) "personalized air", i.e. a small amount of clean air, should be served gently, close to the breathing zone of each individual; and 5) individual control of the thermal environment should be provided. These principles of excellence are compatible with energy efficiency and sustainability.     

Mobilization of lead from human bone tissue during pregnancy and lactation--a summary of long-term research

The skeleton is potential endogenous source of lead during pregnancy and lactation. We have undertaken a longitudinal investigation into the mobilization of lead from the human maternal skeleton to determine whether lead is mobilized from the maternal skeleton during pregnancy and lactation, and if so, when and how much is released. Subjects in the study were migrants to Australia (n=15) whose skeletal lead isotopic composition (endogenous lead) was different to that prevailing in the Australian environment (exogenous lead). This migrant cohort was compared with 6 multi-generational Australian controls. Biological and environmental samples were taken pre-pregnancy where possible, throughout pregnancy and postpartum for at least 6 months. Newly-born infants of the migrant and Australian mothers were monitored for 6 months. Blood lead concentrations for the migrant mothers ranged from 1.5 to 20 microg/dl (geometric mean 2.8) and for Australian mothers ranged from 1.9 to 4.3 microg/dl (geometric mean 2.9). There was minimal change in lead isotopic composition of the Australian pregnant controls although there were increases of approximately 40% in blood lead concentration in 3 of 6 cases during the postpartum period and from 0 to 12% in the other 3. In the migrant pregnant subjects, the geometric mean skeletal lead contribution to blood lead using the isotopic composition was approximately 33% (range 10-88%) for 14 subjects using a revised estimate for exogenous lead. Skeletal contribution to blood lead during the postpartum period was significantly greater than during pregnancy (P<0.001). The skeletal contributions to blood lead are higher and the changes are more consistent in those subjects who conceived within 100 days of arrival in Australia compared with those who conceived longer than 100 days. In the migrant subjects, changes in blood lead concentration during pregnancy and postpartum varied from subject to subject with an overall 20% increase; the increases during the postpartum period were greater than during pregnancy (P<0.001). It was estimated that the amount of maternal skeletal lead mobilized during pregnancy and transferred to the infant via cord blood averaged approximately 79%. The increased skeletal contribution to blood lead is attributed to a low daily calcium intake of approximately 500 mgCa/day, a condition which was present in both migrant and Australian subjects. An ongoing clinical trial is providing a new cohort with calcium supplements. A summary of other aspects of the study is included and covers: additional flux released from the skeleton during pregnancy and postpartum; XRF bone lead results; urinary excretion of lead during pregnancy and postpartum; dietary contribution to blood lead in female adults and children; comparison of rates of exchange of lead in blood of newly-born infants and mothers; relationships of lead in breast milk to lead in blood, urine and diet of the infant and mother; changes in blood lead after cessation of breastfeeding; urinary lead isotopes during pregnancy and postpartum indicate no preferential partitioning of endogenous lead into plasma; a comparison of some aspects of the nonhuman primate and human pregnancy studies.     

ASSESSING AND MANAGING THE RISKS OF PATHOGEN TRANSFER FROM LIVESTOCK MANURES INTO THE FOOD CHAIN

A review was undertaken of (a) the levels and prevalence of Salmonella spp., Campylobacter spp., Listeria monocytogenes, Escherichia coli 0157. Cryptosporidium parvum and Giardia intestinalis in livestock manure, and (b) factors which affect their survival during storage and following land application. Pathogens are commonly present in livestock manures and can survive in soil for several months or years after spreading or excretion onto land. Temperature was identified as being the most important factor influencing pathogen survival, although pH, UV light and drying were also important. Various practical measures to minimise the risk of pathogen transfer into the food chain were identified, including treatment, extended storage and no/harvest periods following land spreading. Guidelines are being developed on managing farm manures to minimise the risks of microbiological contamination of ready-to-eat crops.     

Use of driven piles in rammed holes during construction in soils prone to slump-type settlement

Conclusions The experiment with the use of piles cast in rammed holes in lieu of continuous foundations placed on a bed compacted by tamping produced positive results and will be expanded upon further, since the strength properties of the materials in the foundations and the soils in the foundation beds can be more fully utilized, the reliability of the structure increased, the volume of earthwork reduced, labor and material outlays diminished, and the rate of construction and the level of the industrial nature of the work increased.State Institute for the Projection of the Greenhouse Industry. Translated from Osnovaniya, Fundamenty i Mekhanika Gruntov, No. 2, p. 10, March–April, 1977.     

Design Water Levels in Tidal River Systems under the Influence of Typhoons

Water levels in tidal rivers are subject to the influence of both fluvial and tidal factors. The interaction between these factors is rendered more complex in regions affected by typhoons, which typically result in the combined occurrence of heavy rainfall and high sea levels.
Previous studies have outlined an analytical approach for calculating design water levels based on dividing the fluvial and tidal series into a typhoon and a non-typhoon component. This paper illustrates the steps involved in the analytical approach and describes its application to drainage basins in Hong Kong.
The approach provides a practical means for calculating design water levels, and is recommended for final design purposes. The results of using the full analysis may be approximated by using a sub-set of analytical results, and should prove satisfactory for the purposes of outline design.     

Compartment tests of polyurethane foam seating assemblies

Data from compartment tests of polyurethane foam seating assemblies are reported. Results show that the behavior of such assemblies during fires is strongly dependent on the type and position of interliners and upholstery fabrics. An incidental comparison of peak rate of heat release obtained in a compartment test with a predictive model equation is made and selected data from the tests are presented.     

The development of macrolayer thickness of water in the pool boiling regime

ABSTRACT

The main purpose of this study is to analyse the phenomenon of pool boiling in water over a horizontally placed copper tube heater of 28?mm diameter. The experiment has been carried out to observe the bubble growth and departure characteristics for the heat flux range up to 40,000?W/m². The entire process is being recorded by a digital camera at different time intervals. The measured parameters have been used to determine the initial layer thickness, macro layer thickness and critical heat flux and validated with models proposed in the literature.     

Levels of copper in the urine of women from nonpolluted farming regions of Japan.

Nearly 1500 spot urine samples were collected in the winter of 1987-1988 from women of seven farming prefectures located throughout Japan. Samples were analyzed for copper by flameless atomic absorption spectrometry. The copper content of the urine samples (Cu-U) distributed log-normally with a geometric mean (geometric standard deviation) of 36.9 (1.47) micrograms/l after adjustment for the specific gravity of urine of 1.016. The 95% confidence range was 17.1-79.7 micrograms/l. Neither alcohol consumption nor smoking habit affected the Cu-U. A literature survey showed that the observed level appears to be somewhat higher than previously reported values.     

Results of evaluation of the strength of concrete placed in the shafts of cast-in-place piles

Conclusions 1. Application of the method of underwater concreting with the use of a container is inexpedient in connection with the presence of a large number of flaws detected in the shafts of cast-in-place piles formed by this method; concreting of holes by the VAT method is preferable.2. The strength of concrete in the shafts of cast-in-place piles increases, reaching a maximum at a depth of 0.4–0.5 the length of the shaft. Variation in strength along the shaft is explained primarily by the percentage of coarse aggregate contained in the concrete.3. The quality of pile concrete should be monitored during all stages of pile installation, and, primarily during the stage of concreting, i.e., when there is a chance of correcting an observed defect.All-Union Institute for the Design and Planning of Health Resorts. Scientific-Research Institute of Foundations and Underground Structures. Translated from Osnovaniya, Fundamenty i Mekhanika Gruntov, No. 5, pp. 14–17, September–October, 1976.