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91.
Thanawala S Palyvoda O Georgiev DG Khan SP Al-Homoudi IA Newaz G Auner G 《Journal of materials science. Materials in medicine》2007,18(9):1745-1752
Functional neural stimulation requires good interface between the neural cells and the electrode surfaces. In order to study
the effect of electrode materials and surface structure on cell adhesion and biocompatibility, we cultured cortical neurons
on thin films of platinum and iridium oxide. We used both flat, as-deposited and laser micro-structured films. The laser micro-structuring
consisted of creating regular arrays of micro-bumps or holes with diameters of 4–5 μm and height of about 1.5 μm. The micro-bumps
were fabricated onto platinum and iridium film surfaces deposited on borosilicate glass substrates, using mask-projection
irradiation with single nano-second pulses from a KrF excimer laser (λ = 248 nm). Amorphous and crystalline (deposited at
250 °C) IrO2 films were deposited onto the laser micro-structured iridium films by pulsed-DC reactive sputtering to obtain micro-structured
IrO2 films. Cortical neurons isolated from rat embryo brain were cultured onto these film surfaces. Our results indicate that
flat and micro-structured film surfaces are biocompatible and non-toxic for neural cell growth. The use of poly-d-lysine as a mediator for cell adhesion onto the thin film surfaces is also discussed. 相似文献
92.
Gert Bartzsch Rennie Christian Soumya Ranjan Mohanty Ajay Kumar Shukla Olena Volkova 《国际钢铁研究》2023,94(6):2200798
The influence of Al2O3 in the range of 10–20 mass% and TiO2 in the range of 0.55–5 mass% on the flow behavior, viscosity, density, and surface tension of molten industrial blast furnace slag with CaO/SiO2 = 1.13 is investigated using a high-temperature microscope, a rotating viscometer, and the maximum bubble pressure method. The measurement results show that Al2O3 acts as a network former in the studied CaO–SiO2–MgO–Al2O3–TiO2 slags. With an increase in the Al2O3 content from 10 to 20 mass%, the viscosity and surface tension of the slags increase and the density decreases. In contrast to Al2O3, the TiO2 acts as a surfactant and network breaker in the range of up to 15 mass%. The addition of TiO2 up to 15 mass% results in a decrease in the viscosity in the liquid-dominated region and a decrease in the surface tension of the studied slags. Therefore, the density increases with the addition of TiO2 due to increasing molar volume. The behavior of the breakpoint temperature on all the viscosity curves is in complete agreement with the behavior of the flow point temperature and crystallization temperatures of melilite and perovskite. 相似文献
93.
Valentina Vasta Alessandro Priolo Manuel Scerra Katharine G. Hallett Jeffrey D. Wood Olena Doran 《Meat science》2009
The aims of this study were to investigate the effect of feeding system and of supplementation of tannins (8.93% DM) on the relationship between intramuscular fat content, fatty acid composition and Δ9desaturase (Δ9d) protein expression in longissimus dorsi muscle of lamb. Twenty-eight Comisana lambs (age 45 days) were fed either vetch (Vicia sativa) or concentrate. The herbage diet was (i) lower in saturated fatty acids (especially in C16:0), C18:1 n−9 and in C18:2 n−6; (ii) higher in C16:1 and C18:3 n−3 when compared to concentrate. Within each feeding system the lambs were divided into two sub-groups, one of which received the diet without tannins supplementation, and the other was fed the diets supplemented with the tannins from Quebracho (Schinopsis lorentzii). The animals were slaughtered at age 105 days. The concentrate feeding system increased (p < 0.01) the total intramuscular fat content and the amount of SFA, MUFA and n−6 PUFA and decreased the level of n−3 PUFA (p = 0.05) when compared to the vetch-fed animals but did not affect Δ9 desaturase protein expression. There was no correlation between Δ9d protein expression and total intramuscular fatty acids, CLA and MUFA level. It was suggested that in ruminants, in contrast to monogastric animals, Δ9d expression does not play the key role in intramuscular fatty acids formation. Tannins supplementation resulted in higher (p < 0.05) muscle levels of transC18:1 and C18:2 n−6. It has also increased Δ9d expression in the case of herbage-based diet but not in the case of concentrate-based diet. The mechanism of tannins action on the enzyme expression needs to be elucidated. 相似文献
94.
Risovic V Man D Sivak O Lee SD Wasan KM 《Drug development and industrial pharmacy》2006,32(5):609-615
Purpose: The purpose of this study was to assess the lipid lowering and plasma cholesteryl ester transfer protein (CETP) activity following administration of simvastatin to rabbits fed a high fat/cholesterol diet. Methods: Male New Zealand white rabbits were housed in individual cages and fed a standard diet for 7 days. After 7 days, animals were fed 10 g of a regular chow diet plus 100 g of the same diet supplemented with 0.5% (w/v) cholesterol and 14.0% (w/v) coconut oil for 28 days. Following 28 days on this diet, the animals were randomized based on plasma cholesterol and triglyceride levels, into a group of control animals and a group (n = 6) of animals fed 100 g of cholesterol/coconut diet plus 10 g regular chow diet containing simvastatin (3 mg/kg/day) for an additional 28 days. Blood samples were taken from the marginal ear vein prior to and 28 days after the initiation of drug treatment. Plasma was harvested and stored at 4°C prior to lipid analysis. Plasma total cholesterol and triglyceride levels were quantified using enzymatic kits. HDL (high-density lipoproteins) cholesterol levels were determined using the dextran sulfate-Mg2+ precipitation method. ApoB cholesterol levels were determined by subtracting total cholesterol from HDL cholesterol. Cholesteryl ester transfer protein (CETP) activity was determined by standard assay methods. Results: We observed that simvastatin significantly reduced total plasma cholesterol, triglyceride, and apoB cholesterol compared to non-treated controls. Simvastatin treatment did not alter serum CETP activity compared to non-treated controls. Conclusions: These findings suggest that decreasing plasma lipid levels by treatment with simvastatin is not due to changes in serum CETP activity in rabbits fed a high fat/cholesterol diet. 相似文献
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The range of titanium dioxide (TiO2) samples, modified by β‐cyclodextrin containing copolymers was synthesized. The copolymers obtained were investigated by different methods, such as ultraviolet‐, Fourier transform infrared‐spectroscopy, thermal mass spectroscopy, thermogravimetric analysis, transmission electron microscopy, and scanning electron microscopy. The modification of TiO2 is shown to promote a significant positive impact on the process of methyl orange absorption and photodegradation on its surface. The modified TiO2‐photocatalysts prepared in such way could be promising objects for water purification from organic pollutants. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018 , 135, 46373. 相似文献
99.
Roik Nadiia V. Dziazko Marina O. Trofymchuk Iryna M. Oranska Olena I. 《Journal of Porous Materials》2022,29(2):317-330
Journal of Porous Materials - Templated sol–gel synthesis of silica materials with hexagonally ordered mesoporous structure was realized in the presence of amphiphilic organic compounds (azo... 相似文献
100.