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21.
The present study was designed to examine the effects of EFA deficiency (EFAD) on biochemical, functional, and structural
aspects of the kidney in growing and adult rats fed a normal or EFAD diet for 9 wk after weaning. Food and fluid intake (FI),
urine volume, and Na+ and K+ excretions were measured weekly from weeks 4 to 8 by placing the rats in individual metabolic cages for 24 h. At week 9,
Li+ and a 5% water load, respectively, were administered at 14 and 1.5 h prior to glomerular and proximal tubular function studies,
as assessed by 3-h creatinine (CCr) and Li+ (CLi+) clearances. Hematocrit and urine volume; serum and urine [Cr], [Li+], [Na+], and [K+]; and renal FA distribution were also measured. Data [corrected to 100 g/body weight (bw) and presented as means ±SEM] were
significant, at P<-0.05. Despite a similar ingestion of solids from weeks 4 to 7 (weeks 7 to 10 of life), the rats on the EFAD diet showed
a decreased body weight from week 5. From weeks 4 to 8, Fl and urine volume were similar for both groups, but the Fl increased
at week 6 in the EFAD group; 24-h Na+ and K+ excretions were similar at all weeks, except for an increase in the EFAD group for both ions at week 7. In the EFAD group,
CCr and CLi+ decreased by 27 and 56.3%, respectively (385.7±33.4 vs. 280±21.1, and 21.0±2.1 vs. 9.2±1.1 μL/min/100 g; n=9 vs. 10), the latter result suggesting increased proximal reabsorption. The 3-h Na+ and K+ excretions were similar, but the Li+ decreased (0.78±0.06×10−2 vs. 0.32±0.03×10−2 μeq/min/100 g) in the EFAD group, giving additional support to the suggestion. Renal structure was normal and similar for
both groups, but the EFAD group showed a more prominent proximal tubule brush border, together with heavier periodic acid-Schiff
staining in all specimens from weeks 5 to 9. In the EFAD group, FA of the n−9 and n−7 series were higher, but most of the
n−6 series were lower as a percentage of total lipids in the medulla and cortex. Medullary levels of 20∶4n−6 were maintained,
22∶4n−6 declined twice, arachidonic acid was maintained, and 20∶5n−3 was lower. The EFAD diet affected glomerular function,
proximal tubular structure and function, and FA distribution in the rat kidney. 相似文献
22.
Agnes F. Martins Sergio M. de Meneses Leila L. Y. Visconte Regina C. R. Nunes 《应用聚合物科学杂志》2004,92(4):2425-2430
Vulcanized composites of chloroprene rubber (CR) with cellulose II (Cel II) as a filler were investigated. Cel II, obtained by the coagulation of cellulose xanthate, was incorporated in the rubber by the traditional method. The filler content varied from 0 to 30 phr. For comparison purposes, carbon black (CB)–CR composites were also studied. The CB amount varied from 0 to 45 phr. The mechanical and dynamic mechanical properties were determined, and the CR composite containing 20 phr of Cel II showed the best set of properties. © 2004 Wiley Periodicals, Inc. J Appl Polym Sci 92: 2425–2430, 2004 相似文献
23.
Thermotropic polyesters prepared from series of 4,4-dihydroxy-,w-diphenoxy alkanes and 4,4-dichloroformyl-,w-diphenoxy alkanes are well known. The substitution of a methylenic spacer by an oxyethylenic spacer in the main chain of these polyesters drastically modifies their physical properties, particularly the mesogenic transition temperatures, as can be observed by DSC and thermooptical analysis. The thermal stability and the polymer solubility in common organic solvents of these polymers did not show a significant change. The physical properties of the two thermotropic polyesters prepared in diphenyl ether were evaluated. 相似文献
24.
Larissa S. Martins Noelle C. Zanini Alexandre L. S. Botelho Daniella R. Mulinari 《Polymer Engineering and Science》2021,61(7):2055-2065
Oil spill accidents in marine environments and the lack of disposal of post-consumer plastic are environmental problems worldwide. This study presents a sustainable alternative for both issues through envelopes filled with microplastics (MPs) from recycled bags for the sorption of spilled crude oil. Through particle size analysis by three different sieves (4, 9, and 20 mesh), different MP sizes were characterized by scanning electron microscope (SEM), Brunauer–Emmett–Teller (BET), density, contact angle (CA), and Fourier-transform infrared spectroscopy (FTIR). According to their sizes, the MPs were distributed in envelopes and submitted to crude oil sorption capacity and efficiency evaluation. Three MP particle sizes were obtained (from the largest to the smallest, according to the sieve mesh, MP4, MP9, and MP20). SEM images of samples exhibited irregular and porous surfaces, and MP4 had the smallest pore size (8.6 μm). BET showed that MP4 had the highest surface area (0.074 m2/g). The CA > 90° exposed that all samples were hydrophobic. FTIR spectrum demonstrated that the samples from the recycled bags were made of high density polyethylene (HDPE). The MP4 envelopes also had the best crude oil sorption results in capacity and efficiency (1.73 g/g and 68%, respectively), being a promising recycled sorbent in crude oil spillage applications. 相似文献
25.
Expert finding is an information retrieval task that is concerned with the search for the most knowledgeable people with respect to a specific topic, and the search is based on documents that describe people's activities. The task involves taking a user query as input and returning a list of people who are sorted by their level of expertise with respect to the user query. Despite recent interest in the area, the current state‐of‐the‐art techniques lack in principled approaches for optimally combining different sources of evidence. This article proposes two frameworks for combining multiple estimators of expertise. These estimators are derived from textual contents, from graph‐structure of the citation patterns for the community of experts and from profile information about the experts. More specifically, this article explores the use of supervised learning to rank methods, as well as rank aggregation approaches, for combining all of the estimators of expertise. Several supervised learning algorithms, which are representative of the pointwise, pairwise and listwise approaches, were tested, and various state‐of‐the‐art data fusion techniques were also explored for the rank aggregation framework. Experiments that were performed on a dataset of academic publications from the Computer Science domain attest the adequacy of the proposed approaches. 相似文献
26.
27.
Andrew B. Lambe Joaquim R. R. A. Martins 《Structural and Multidisciplinary Optimization》2016,53(3):589-603
In structural optimization subject to failure constraints, computing the gradients of a large number of functions with respect to a large number of design variables may not be computationally practical. Often, the number of constraints in these optimization problems is reduced using constraint aggregation at the expense of a higher mass of the optimal structural design. This work presents results of structural and coupled aerodynamic and structural design optimization of aircraft wings using a novel matrix-free augmented Lagrangian optimizer. By using a matrix-free optimizer, the computation of the full constraint Jacobian at each iteration is replaced by the computation of a small number of Jacobian-vector products. The low cost of the Jacobian-vector products allows optimization problems with thousands of failure constraints to be solved directly, mitigating the effects of constraint aggregation. The results indicate that the matrix-free optimizer reduces the computational work of solving the optimization problem by an order of magnitude compared to a traditional sequential quadratic programming optimizer. Furthermore, the use of a matrix-free optimizer makes the solution of large multidisciplinary design problems, in which gradient information must be obtained through iterative methods, computationally tractable. 相似文献
28.
A density-based partitioning strategy is proposed for large domain networks in order to deal with the scalability issue found in autonomic networks considering, as a scenario, the autonomic Quality of Service (QoS) management context. The approach adopted focus as on obtaining dense network partitions having more paths for a given vertices set in the domain. It is demonstrated that dense partitions improve autonomic processing scalability, for instance, reducing routing process complexity. The solution looks for a significant trade-off between partition autonomic algorithm execution time and path selection quality in large domains. Simulation scenarios for path selection execution time are presented and discussed. Authors argue that autonomic networks may benefit from the dense partition approach proposed by achieving scalable, efficient and near real-time support for autonomic management systems. 相似文献
29.
Pedro Martins Rui Caseiro Jorge Batista 《Computer Vision and Image Understanding》2013,117(3):250-268
This work addresses the matching of a 3D deformable face model to 2D images through a 2.5D Active Appearance Models (AAM). We propose a 2.5D AAM that combines a 3D metric Point Distribution Model (PDM) and a 2D appearance model whose control points are defined by a full perspective projection of the PDM. The advantage is that, assuming a calibrated camera, 3D metric shapes can be retrieved from single view images. Two model fitting algorithms and their computational efficient approximations are proposed: the Simultaneous Forwards Additive (SFA) and the Normalization Forwards Additive (NFA), both based on the Lucas–Kanade framework. The SFA algorithm searches for shape and appearance parameters simultaneously whereas the NFA projects out the appearance from the error image and searches only for the shape parameters. SFA is therefore more accurate. Robust solutions for the SFA and NFA are also proposed in order to take into account the self-occlusion or partial occlusion of the face. Several performance evaluations for the SFA, NFA and theirs efficient approximations were performed. The experiments include evaluating the frequency of converge, the fitting performance in unseen data and the tracking performance in the FGNET Talking Face sequence. All results show that the 2.5D AAM can outperform both the 2D + 3D combined models and the 2D standard methods. The robust extensions to occlusion were tested on a synthetic sequence showing that the model can deal efficiently with large head rotation. 相似文献
30.
Raquel Santos Mauler Fernando Guaragna Martins Dimitrios Samios 《Polymer Bulletin》1995,35(1-2):151-156
Summary The cleavage of styrene-butadiene rubber (SBR) with periodic acid (H5IO6) and simultaneous injection of ultrasonic radiation has been performed. Two frequencies, 25 and 40 kHz, respectively, have been used. The results demonstrate clearly that 40 kHz ultrasound radiation accelerates significantly the cleavage reaction. The Pearl String Model theory had been used to elucidate this process. 相似文献