Binary‐offset‐carrier modulation techniques with applications in satellite navigation systems

An important aspect in designing the modulation scheme for various satellite systems, such as the modernized GPS and Galileo, is to obtain good spectral properties and suitable spectral shaping. For example, in the future satellite navigation systems, some of the main goals are: low interference with the existing GPS signals, good root‐mean‐square (RMS) bandwidth, good time resolution (in order to allow the separation between channel paths and to decrease the synchronization errors) etc. Starting from the recently proposed cosine‐ and sine‐BOC modulation families for GPS and Galileo systems, we introduce a new, generalized family, denoted here by double‐BOC (DBOC) modulation. We derive and analyze the properties of the power spectral densities (PSD) and autocorrelation functions (ACF) of the DBOC modulation with various orders, we show its relationship with BPSK, sine‐ and cosine‐BOC modulations, and we illustrate via several examples how to choose optimally the parameters of this new modulation family, according to different optimization criteria. The examples are targeting at applications such as the design of suitable modulations for Galileo open service (OS) and public regulated service (PRS) signals, but the authors believe that the DBOC concept might be useful to other satellite‐based applications, when the available bandwidth is large enough. Copyright © 2006 John Wiley & Sons, Ltd.     

Organochlorine pesticides in colostrums in case of normal and preterm labor (IASI, Romania)

Assessment of organochlorine pesticides (OCPs) in human body is important for human health because they have weak estrogenic or antiestrogenic effects and are considered endocrine disrupters. We used colostrum of women as indicator for levels of OCPs in human body for mothers with normal and preterm labor from eastern part of Romania. Sixty- three samples of colostrum were extracted by solid-phase extraction. Analyses were carried out using gas chromatography coupled to mass spectrometry (GC-MS). OCPs have been detected in all samples, with p,p’-dichlorodiphenyldichloroethylene (p,p’-DDE) and γ-hexachlorocyclohexane (γ-HCH) being at the highest concentrations. Of the organochlorines measured in clostrum samples from women in preterm labor, median levels of DDTs (470 ng/g) and HCHs (99 ng/g) were higher than for the same compounds from women in normal labor (median of DDTs = 268 ng/g and median of HCHs = 96 ng/g). Normal labor had higher median concentrations of HCB (19.5 ng/g) versus preterm labor (14 ng/g). Statistical data show high Spearman correlation coefficients between various OCPs. We found a good correlation between α-, γ-, β- and δ- HCH isomers (p < 0.001) for both normal and preterm labor. The most abundant target compound was p,p’-DDE (median value 96 ng/g, and 137 ng/g for mother with normal and preterm labor, respectively) in all colostrum samples. The estimated daily intakes of HCHs by infants exceeded corresponding Health Canada guidelines.     

Innovation at the end of the life cycle: discontinuous innovation strategies by incumbents

This paper focuses on the strategies of incumbents that seek to develop discontinuous innovations within the boundaries of a mature innovation system. Mature innovation systems do not provide support for these discontinuous innovations. This article focuses on exploring why incumbents in these setting engage in discontinuous innovation and what strategies they deploy to become successful. We analyse 10 cases of incumbents developing discontinuous innovations in the mature Dutch greenhouse horticulture sector. The results of our analysis show that the incumbents are primarily triggered by dissatisfaction with the current way of doing business and that the existing institutions are the main barrier to discontinuous innovation. In response, the incumbents try to circumvent the existing innovation system in their innovation process, but when successful also engage in changing the existing innovation system. This paper contributes to the understanding of the role of incumbents as source of discontinuous innovation in mature innovation systems.     

Texture anisotropy technique in brain degenerative diseases

Structural alterations anisotropy-based measured for different areas for the most common types of dementia diseases could be a biomarker of brain impairment. The current work aims to assess whether texture anisotropy can discriminate both healthy versus Alzheimer’s and Pick’s patients based on regional evaluation while maintaining high predictive power. The investigated area is reduced from the whole-brain surface to three major lobes (i.e., frontal, temporal and parietal). A predictive model was proposed to associate a disease with a specific area in the brain based on the anisotropy values. Simultaneous analysis of 1680 measurements from 105 brain magnetic resonance images acquired as T2w and PD sequences was performed to establish the significance of the model. The cerebral calcinosis disease has been used as artificial ground truth. The association based on textural anisotropy between targeted diseases and control patients was performed by using Pearson’s correlation coefficients. A new proposed consistency index investigated the texture anisotropy relevance for all image’s types and all analyzed classes and regions. The validation study is based on area under the receiver-operating characteristic curve that depicted the overall diagnostic performance of the texture anisotropy in each region. The proposed model demonstrated that texture anisotropy is accurate solution in diagnosis of Alzheimer’s and Pick’s diseases when the investigated area is reduced to major lobes, with sensitivity >90% and specificity >80%.

     

Explaining the failure of the Dutch innovation system for biomass digestion—A functional analysis

Since the 1970s research on energy conversion technologies, such as biomass digestion, has been carried out in the Netherlands. However, after 30 years biomass digestion has not been implemented on large scale. The aim of this paper is to create insight into the underlying factors of this troublesome trajectory by applying the ‘Functions of Innovation Systems’ framework. This results in clear understanding of the (lack of) activities that took place in the innovation system of biomass digestion and the role of government policy in both inducing and blocking this development. The analysis provides several lessons to take into account when developing policies for the acceleration of the development and diffusion of biomass energy.     

SYBRGreenER™ Real-Time PCR to detect almond in traces in processed food

Because food ingredients are sometimes considered as causative factors in IgE mediated food allergies, DNA-based tests may prove to be very useful to establish whether allergenic species have been used in foodstuffs production. The development of two SYBR^®GreenER™ Real-Time PCR assays, targeting Pru 1 and rbcL genes, based on melting curve analysis, to detect allergen species in food has been presented. Applicability of these methods was assessed with several commercial products containing processed almond.     

Characterization of melanoidins from a glucose-glycine model system

The properties of melanoidins prepared from glucose and glycine (GG) were investigated by a three step purification protocol consisting of dialysis, gel filtration at high ionic strength and ion metal affinity chromatography. The high molecular weight fraction obtained in the GG system is responsible for 80% of the total brown colour and its antioxidative ability was about 1/4 of that of Trolox measured by the inhibition of linoleic acid oxidation. GG melanoidins have good affinity towards Cu (II) (32% bound to the resin) while it is much lower towards Pb (II) (10%) and Fe (II) (5%). Capillary zone electrophoresis analysis suggests that GG melanoidins are positively charged, although no signal was observed analysing melanoidins by matrix-assisted laser desorption-ionisation time-of-flight mass spectrometry (MALDI-TOF/MS).     

Carotenoids from tomatoes inhibit heterocyclic amine formation

Tomatoes are a rich source of antioxidants and they are commonly used for meat cooking in Mediterranean countries. The effects of tomato antioxidants on the formation of carcinogenic/mutagenic heterocyclic amines were investigated. A liquid model system containing as precursors creatinine, glucose and glycine in molar concentrations comparable to those present in bovine meat (chemical model system) was employed. A freeze-dried bovine meat juice (meat juice model system) was also used for some experiments. In both model systems, an inhibiting effect of tomato carotenoid fraction on the formation of imidazoquinolines (IQx, MeIQx and DiMeIQx) was observed. Using carotenoid extract at a concentration of 1000 ppm, inhibitions of 36% and 11% of IQx and MeIQx formation respectively in the chemical system and of 13% of MeIQx and of 5% of 4,8-DiMeIQx in the meat juice system was observed. The effect of the main tomato flavonoid, quercetin, was investigated using the meat juice system. Quercetin gave an inhibition of MeIQx formation between 9% and 57% with a maximum effect of 67% at 10 ppm.     

变截面Euler-Bernoulli梁在轴力作用下固有振动的级数解

建立了截面特性、轴力和质量分布均连续变化的Euler-Bernoulli梁固有振动方程。采用Frobeniu方法求解方程,得到了方程的级数解析解;并计算了结构的振动频率与振型。算例证明了该方法的有效性,并表明轴向力的几何非线性效应对振动的低阶频率和自振振型有一定的影响,级数项数的取值对算法的收敛性有影响。