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71.
This paper examines the impact of SiGe HBT scaling on 1/f noise and phase noise of oscillators and frequency synthesizers. The increase of transistor speed with scaling is shown to significantly increase the sensitivity of oscillation frequency to 1/f noise and, thus, degrade close-in phase noise, but decrease the sensitivity of oscillation frequency to base current shot noise and base resistance thermal noises. The results show that corner offset frequency defined by the intersect of the 1/f3 and 1/f2 phase noise has little to do with the traditional 1/f corner frequency. The relative importance of individual noise sources in determining phase noise is examined as a function of technology scaling, device sizing, and oscillation frequency. The collector current shot noise and base resistance noise are shown to set the fundamental limits of phase noise reduction. A methodology to identify the maximum tolerable 1/f K factor is established and demonstrated for the HBTs used  相似文献   
72.
Near infrared (n.i.r.) reflectance spectroscopy has been employed for the determination of protein, fat and moisture in sliced white bread. N.i.r. reflectance at six wavelengths was measured using circular samples from each of six alternate slices taken from one half of each of 30 loaves of different composition. The six readings for each loaf at each wavelength were averaged and used to produce calibrations which, on prediction of the compositions of a further 30 loaves sampled in the same way, gave rise to standard deviations of differences between n.i.r. and standard procedures of 0.20% for protein, 0.18% for fat and 0.51% for moisture. Calibrations derived from the other halves of the loaves, which had been air-dried and ground to a powder, resulted in similar standard deviation of differences for protein and fat.  相似文献   
73.
74.
Cell encapsulation within hydrogel droplets is transforming what is feasible in multiple fields of biomedical science such as tissue engineering and regenerative medicine, in vitro modeling, and cell-based therapies. Recent advances have allowed researchers to miniaturize material encapsulation complexes down to single-cell scales, where each complex, termed a single-cell microgel, contains only one cell surrounded by a hydrogel matrix while remaining <100 μm in size. With this achievement, studies requiring single-cell resolution are now possible, similar to those done using liquid droplet encapsulation. Of particular note, applications involving long-term in vitro cultures, modular bioinks, high-throughput screenings, and formation of 3D cellular microenvironments can be tuned independently to suit the needs of individual cells and experimental goals. In this progress report, an overview of established materials and techniques used to fabricate single-cell microgels, as well as insight into potential alternatives is provided. This focused review is concluded by discussing applications that have already benefited from single-cell microgel technologies, as well as prospective applications on the cusp of achieving important new capabilities.  相似文献   
75.
Unlike nearly all engineered materials which contain bonds that weaken under load, biological materials contain “catch” bonds which are reinforced under load. Consequently, materials, such as the cell cytoskeleton, can adapt their mechanical properties in response to their state of internal, non-equilibrium (active) stress. However, how large-scale material properties vary with the distance from equilibrium is unknown, as are the relative roles of active stress and binding kinetics in establishing this distance. Through course-grained molecular dynamics simulations, the effect of breaking of detailed balance by catch bonds on the accumulation and dissipation of energy within a model of the actomyosin cytoskeleton is explored. It is found that the extent to which detailed balance is broken uniquely determines a large-scale fluid-solid transition with characteristic time-reversal symmetries. The transition depends critically on the strength of the catch bond, suggesting that active stress is necessary but insufficient to mount an adaptive mechanical response.  相似文献   
76.
The future of green electronics possessing great strength and toughness proves to be a promising area of research in this technologically advanced society. This work develops the first fully bendable and malleable toughened polylactic acid (PLA) green composite by incorporating a multifunctional polyhydroxybutyrate rubber copolymer filler that acts as an effective nucleating agent to accelerate PLA crystallization and performs as a dynamic plasticizer to generate massive polymer chain movement. The resultant biocomposite exhibits a 24‐fold and 15‐fold increment in both elongation and toughness, respectively, while retaining its elastic modulus at >3 GPa. Mechanism studies show the toughening effect is due to an amalgamation of massive shear yielding, crazing, and nanocavitation in the highly dense PLA matrix. Uniquely distinguished from the typical flexible polymer that stretches and recovers, this biocomposite is the first report of PLA that can be “bend, twist, turn, and fold” at room temperature and exhibit excellent mechanical robustness even after a 180° bend, attributes to the highly interconnected polymer network of innumerable nanocavitation complemented with an extensively unified fibrillar bridge. This unique trait certainly opens up a new horizon to future sustainable green electronics development.  相似文献   
77.
The adoption of epidermal electronics into everyday life requires new design and fabrication paradigms, transitioning away from traditional rigid, bulky electronics towards soft devices that adapt with high intimacy to the human body. Here, a new strategy is reported for fabricating achieving highly stretchable “island‐bridge” (IB) electrochemical devices based on thick‐film printing process involving merging the deterministic IB architecture with stress‐enduring composite silver (Ag) inks based on eutectic gallium‐indium particles (EGaInPs) as dynamic electrical anchors within the inside the percolated network. The fabrication of free‐standing soft Ag‐EGaInPs‐based serpentine “bridges” enables the printed microstructures to maintain mechanical and electrical properties under an extreme (≈800%) strain. Coupling these highly stretchable “bridges” with rigid multifunctional “island” electrodes allows the realization of electrochemical devices that can sustain high mechanical deformation while displaying an extremely attractive and stable electrochemical performance. The advantages and practical utility of the new printed Ag‐liquid metal‐based island‐bridge designs are discussed and illustrated using a wearable biofuel cell. Such new scalable and tunable fabrication strategy will allow to incorporate a wide range of materials into a single device towards a wide range of applications in wearable electronics.  相似文献   
78.
The Enhanced Traffic Management System (ETMS) is a legacy system used by the Federal Aviation Administration (FAA) to support air traffic flow management. Air traffic flow management is the strategic control of air traffic to minimize delays and congestion and maximize the throughput of aircraft throughout the National Airspace System (NAS). This paper discusses the reasons for modeling a legacy system, problems and advantages encountered in modeling an operational system, and describes the construction of a simulation model of ETMS. Originally written in Pascal to run on Apollo workstations under the Aegis Domain operating system, ETMS has been converted to C/C++ and ported to HP servers and workstations running HP-UX, a POSIX-compliant version of UNIX. The objectives of the modeling task were to assess performance of the ported system and to provide a basis for evaluating a possible redesign/re-architecture of the system. The initial plan was to develop one or two models aimed at the network aspects (both LAN and WAN) of ETMS at a relatively high level, and then to develop a more detailed model to look at specific workstation/server issues.As is shown in this paper, issues of existing system design and documentation and the availability (or the lack) of data continually arose. Nevertheless, a reasonable set of working assumptions were derived which allowed modeling and evaluation to proceed. Thus, the quantitative and qualitative results obtained provided information and lessons learned that can be built upon. Moreover, the second of the stated goals (to provide a basis for possible redesign) was also achieved because there is now a baseline for future design/architecture studies. The focus of this paper is to provide insights into the issues involved in modeling an existing system rather than the results of the model itself.  相似文献   
79.
MOSFETs and MOSCs incorporating HfO2 gate dielectrics were fabricated. The IDSVDS, IDSVGS, gated-diode and CV characteristics were investigated. The subthreshold swing and the interface trap density were obtained. The surface recombination velocity and the minority carrier lifetime in the field-induced depletion region measured from the gated diodes were about 2.73 × 103 cm/s and 1.63 × 10−6 s, respectively. The effective capture cross section of surface state was determined to be 1.6 × 10−15 cm2 using the gated-diode technique in comparison with the subthreshold swing measurement. A comparison with conventional MOSFETs using SiO2 gate oxide was also made.  相似文献   
80.
The growing power demands of wearable electronic devices have stimulated the development of on‐body energy‐harvesting strategies. This article reviews the recent progress on rapidly emerging wearable biofuel cells (BFCs), along with related challenges and prospects. Advanced on‐body BFCs in various wearable platforms, e.g., textiles, patches, temporary tattoo, or contact lenses, enable attractive advantages for bioenergy harnessing and self‐powered biosensing. These noninvasive BFCs open up unique opportunities for utilizing bioenergy or monitoring biomarkers present in biofluids, e.g., sweat, saliva, interstitial fluid, and tears, toward new biomedical, fitness, or defense applications. However, the realization of effective wearable BFC requires high‐quality enzyme‐electronic interface with efficient enzymatic and electrochemical processes and mechanical flexibility. Understanding the kinetics and mechanisms involved in the electron transfer process, as well as enzyme immobilization techniques, is essential for efficient and stable bioenergy harvesting under diverse mechanical strains and changing operational conditions expected in different biofluids and in a variety of outdoor activities. These key challenges of wearable BFCs are discussed along with potential solutions and future prospects. Understanding these obstacles and opportunities is crucial for transforming traditional bench‐top BFCs to effective and successful wearable BFCs.  相似文献   
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