一种短波宽带定向耦合器的设计

根据变压器串并联同时耦合的原理，提出了一种利用三线变压器魔T和传输线变压器构成定向耦合器的方法，给出了设计原理，设计制作了一种短波宽频带、大功率定向耦合器。并对其参数进行了理论计算和实际测量，测试结果与理论分析吻合，满足设计要求。经过实际应用，验证了设计方法的可行性。     

Oxidative stress, mutant SOD1, and neurofilament pathology in transgenic mouse models of human motor neuron disease

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that primarily affects motor neurons in the spinal cord and brain stem. About 10% of all ALS cases are familial (FALS), inherited in an autosomal dominant manner. One fifth of FALS patients carry mutations in the Cu/Zn superoxide dismutase (SOD1) gene, and several lines of transgenic mice have been engineered to express mutant forms of the SOD1 gene that are linked to FALS. Significantly, many of these transgenic lines of mice develop a motor neuron disease (MND) that resembles human FALS. Oxidative stress induced by human SOD1 mutations is believed to play an important role in the pathogenesis of FALS and the FALS-like MND seen in the mutant SOD1 transgenic mice. For example, two lines of these mice showed prominent degeneration of mitochondria and endoplasmic reticulum in spinal cord neurons. Furthermore, recent studies have shown that neurofilament (NF)-rich spheroids. Lewy body-like NF inclusions, altered ubiquitin immunoreactivity, and Golgi fragmentation occur in the spinal cord motoneurons of these mutant SOD1 transgenic mice. Because these lesions recapitulate hallmark abnormalities of human ALS, mutant SOD1 transgenic mice provide a useful model for studies designed to elucidate the pathogenesis of ALS. Furthermore, transgenic mice that overexpress NF proteins also develop a clinical and pathologic phenotype similar to human MND, and polymorphisms in an NF gene have been linked to patients with ALS. Collectively, these observations implicate NF protein abnormalities in the pathogenesis of this disorder. Accordingly, this review summarizes recent insights into mechanisms of motor neuron degeneration in ALS that have emerged from studies of these new animal models of this neurodegenerative disease.     

A NIC with Impedance Scaling Properties Using Unity Gain Cells

A novel negative impedance converter (NIC) is proposed. This configuration is based on unity gain cells (a cascade of current and voltage followers with unity gains). The proposed circuit has wide band impedance scaling property, and it is suitable for practical implementation of realizing high-negative-valued passive components.     

一种人机交互的大区域路径规划方法

提出了一种在大面积规划区域内为运动物体规划一条从起始点到终点的满意路径的方法。首先通过地形分析，把整个规划区域分成不同类型的子区域；其次在规划区域内选择候选点；最后给出了一种带有运动约束和规划规则的Ａ算法获得所需要的满意路径。     

小波包在弹体侵彻目标试验数据分析中的应用

由于硬目标侵彻载体结构、研究对象和侵彻过程的复杂性,在试验中得到的特征量─加速度信号的频率成分很多,而且都是非平稳的随机过程,是试验过程中各种作用的综合结果。小波理论是新的信号处理技术,小波分析是一种信号的时间-频率分析方法,具有多分辨率分析的特点。本文利用小波包理论将试验数据进行了不同频段的分解,并对相应频段的信号作了相应频谱分析。结果证明,小波分析对于复杂目标识别数据是一种颇为有效的分析工具,试验数据的分析结果对工程实践具有指导意义。     

龙门式电火花线切割译码仿真程序设计

研究了龙门式电火花线切割译码仿真程序，构架了程序框架。对编译模块进行了细分，对仿真模块的层次结构及核心技术的实现做了详细介绍。介绍了二维工件、三维工件刀补的过程。     

一种基于文件系统的报表设计方法

通过宝钢一号高炉大修工程计算机软件设计的实践，分析了在文件系统中报表设计的不足，提供了一种基于文件系统的报表设计方法。     

Interface structure in arsenide/phosphide heterostructun grown by gas-source MBE and low-pressure MOVPE

We have used cross-sectional scanning tunneling microscopy (STM) to study interface structure in arsenide/phosphide heterostructures grown by gas-source molecular beam epitaxy (GSMBE) and by low-pressure metalorganic vapor phase epitaxy (LP-MOVPE). High-resolution images of GSMBE samples consisting of GaAs interrupted at 200Å intervals with a 40 s P₂ flux reveal substantial, growth-temperature-dependent incorporation of phosphorus with nanometer-scale lateral variations in interface structure. STM images of InGaAs/InP multiple quantum well structures grown by LP-MOVPE show evidence of interface asymmetry and extensive atomic cross-incorporation at the interfaces. Data obtained by STM have been corroborated by high-resolution x-ray diffraction and reflection high-energy electron diffraction. Together, these studies provide direct information about nanometer-scale grading and lateral nonuniformity of arsenide/phosphide interfaces that can occur under these growth conditions.     

Coexistence of life threatening chemotherapy related leukoencephalopathy, saggital sinus thrombosis and multiple organ failure in a child with acute lymphoblastic leukemia: an unusual case with clinical recovery

A nine-year old girl with T cell acute lymphoblastic leukemia (ALL) had acute severe neurologic complications at the end of the remission-induction chemotherapy course. Thirty-six hours following triple intrathecal (IT) therapy and intravenous (IV) administration of L-asparaginase (L-asp), tetraplegia developed and she became unconscious. She had bouts of hypertension and persistent tachycardia unresponsive to digitalis therapy. Magnetic resonance imaging (MRI) showed multiple brain white matter hyperintensities and filling defects in the saggital sinus, suggesting thrombosis. Over the 40 days, in addition to her neurologic compromise she also had transient diabetes mellitus, severe hyperlipidemia, hypoproteinemia and edema, liver and heart failure and staphylococcus aureus sepsis with prolonged bone marrow depression. Despite, coexistence of all these chemotherapy related complications, her neurologic functions and multiple organ failure improved gradually. After a 70 days' period of interruption, chemotherapy was resumed and continued without any further complications. Although, the etiology of her extensive sensitivity to some drugs remains unclear, we believe that it is important to document these unusual events in this child.     

Approximate set-valued observers for nonlinear systems

A set-valued observer (SVO) produces a set of possible states based on output measurements and a priori models of exogenous disturbances and noises. Previous work considered linear time-varying systems and unknown-but-bounded exogenous signals. In this case, the sets of possible state vectors take the form of polytopes whose centers are optimal state estimates. These polytopic sets can be computed by solving several small linear programs. An SVO can be constructed conceptually for nonlinear systems; however, the set of possible state vectors no longer takes the form of polytopes, which in turn inhibits their explicit computation. This paper considers an “extended SVO”. As in the extended Kalman filter, the state equations are linearized about the state estimate, and a linear SVO is designed along the linearization trajectory. Under appropriate observability assumptions, it is shown that the extended SVO provides an exponentially convergent state estimate in the case of sufficiently small initial condition uncertainty and provides a nondivergent state estimate in the case of sufficiently small exogenous signals