Conjugate heat transfer in the laminar flow of a swirled incompressible fluid in a horizontal annular duct

The heat transfer associated with swirled flow of a heat-transfer medium in a semi-infinite annular duct is analyzed numerically. The walls of the duct have a finite thickness and exert a significant influence on the formation of the temperature fields in the fluid.Translated from Inzhenerno-Fizicheskii Zhurnal, Vol. 57, No. 5, pp. 713–720, November, 1989.     

Experimental and theoretical study of light scattering by individual mature red blood cells by use of scanning flow cytometry and a discrete dipole approximation

Elastic light scattering by mature red blood cells (RBCs) was theoretically and experimentally analyzed by use of the discrete dipole approximation (DDA) and scanning flow cytometry (SFC), respectively. SFC permits measurement of the angular dependence of the light-scattering intensity (indicatrix) of single particles. A mature RBC is modeled as a biconcave disk in DDA simulations of light scattering. We have studied the effect of RBC orientation related to the direction of the light incident upon the indicatrix. Numerical calculations of indicatrices for several axis ratios and volumes of RBC have been carried out. Comparison of the simulated indicatrices and indicatrices measured by SFC showed good agreement, validating the biconcave disk model for a mature RBC. We simulated the light-scattering output signals from the SFC with the DDA for RBCs modeled as a disk-sphere and as an oblate spheroid. The biconcave disk, the disk-sphere, and the oblate spheroid models have been compared for two orientations, i.e., face-on and rim-on incidence, relative to the direction of the incident beam. Only the oblate spheroid model for rim-on incidence gives results similar to those of the rigorous biconcave disk model.     

Biocompatible dialysis membranes and acute renal failure: a study in post-operative acute tubular necrosis in cadaveric renal transplant recipients

Previous experimental and human data suggests a detrimental effect on the course of acute renal failure related to exposure of blood to artificial dialysis membranes of poor biocompatibility. We performed a 2.5-year prospective randomized trial to compare the clinical course of acute renal failure (post-operative ischemic acute tubular necrosis, ATN) in patients receiving a cadaveric renal transplant requiring supportive hemodialysis in the immediate post-transplant setting. Patients were randomized to either a cuprophane or polymethylmethacrylate (PMMA) conventional hollow fiber dialyzer. All patients received a standard immunosuppressive regimen which included induction therapy with either horse anti-thymocyte gamma globulin (ATGAM) or the murine anti-CD3 monoclonal antibody (OKT3). Of 53 patients randomized, 17 were excluded (2 for intervening biopsy-proven rejection prior to recovery from ATN, 10 for primary graft nonfunction and 5 for other reasons), leaving 36 evaluable cases of uncomplicated ATN, 18 in each group. There was no difference by age, race, gender, cause of ESRD, immunosuppressive regimen, cold or warm ischemia time, use of pre-transplant dialysis, percent oliguria or the incidence of intra-dialytic hypotension between the 2 groups. There was no difference in the mean time to recovery from ATN posttransplant (8.9 days in the cuprophane group vs 9.5 days in the PMMA group, p = NS) or in the average number of hemodialysis treatments required (3.6 in both groups, p = NS). There was also no difference in long term allograft outcome in terms of the nadir serum creatinine, the number of episodes of subsequent acute rejection or in the development of chronic rejection. An intent-to-treat analysis of all 53 originally randomized patients similarly yielded no significant differences. A subsequent, non-randomized study using a membrane of intermediate biocompatibility (Hemophan) also showed no difference in recovery time from ATN. Bioincompatible membranes do not seem to have a significant clinical impact on the course of recovery of this form of acute renal failure. The striking benefits of biocompatibility in the course of ARF seen in other human trials may relate more to the non-renal systemic toxic effects of bioincompatibility.     

Filtration Gas Combustion in a Porous Ceramic Annular Burner for Thermoelectric Power Conversion

A numerical study of the combustion of lean methane/air mixtures in a porous media burner is performed using novelty geometry, cylindrical annular space. The combustion process takes place in the porous space located between two pipes, which are filled with alumina beads of 5.6 mm diameter forming a porosity of 0.4. The outer tube diameter of 3.82 cm is isolated; meanwhile the inner tube of 2 cm in diameter is covered by a continuous set of thermoelectric elements (TE) for transforming heat energy into electricity. To achieve and maintain the proper temperature gradient on TE, convective heat losses are considered from the TE. Computer simulations focus on the two-dimensional (2D) temperature analysis and displacement dynamics of the combustion front inside the reactor, depending on the values of the filtration velocity (0.1 to 1.0 m/s), the heat loss coefficient from the internal cylinder (400–1500 W/m²/K), and the fuel equivalence ratio (0.06– 0.5). The conditions that maximized the overall performance of the process of energy conversion are: 0.7 m/s of the filtration velocity, 0.363 of the fuel equivalence ratio and 1500 W/(m^2·K) of the heat transfer coefficient from the internal cylinder, to obtain 2.05 V electrical potential, 21 W of electrical power, and 5.64% of the overall process efficiency. The study shows that the cylindrical annular geometry can be used for converting the energy of combustion from lean gas mixtures into electricity, with a performance similar to the specified by manufacturers of thermoelectric elements (TE).     

Enzymatic Growth of Quantum Dots: Applications to Probe Glucose Oxidase and Horseradish Peroxidase and Sense Glucose

Three innovative assays are developed for the detection of enzymatic activities of glucose oxidase (GOx) and horseradish peroxidase (HRP) by the generation of CdS quantum dots (QDs) in situ using non‐conventional enzymatic reactions. In the first assay, GOx catalyzes the oxidation of 1‐thio‐β‐D ‐glucose to give 1‐thio‐β‐D ‐gluconic acid. The latter is spontaneously hydrolyzed to β‐D‐gluconic acid and H₂S, which in the presence of cadmium nitrate yields fluorescent CdS nanoparticles. In the second assay HRP catalyzes the oxidation of sodium thiosulfate with hydrogen peroxide generating H₂S and consequently CdS QDs. The combination of GOx with HRP, allowed quantification of glucose in plasma by following growth of fluorescent QDs.     

Combined hydrogen production and power generation from aluminum combustion with water: Analysis of the concept

In this paper the combined production of hydrogen and power based on the aluminum combustion with water is investigated. Furthermore, a concept system is proposed that is potentially able to provide pressurized hydrogen and high temperature steam along with heat and work at the crankshaft. The system demonstrates high energy conversion efficiency, and it fully complies with environment sustainability requirements.     

Infrared fibers for radiometer thermometry in hypothermia andhyperthermia treatment

Hypothermia is a condition which results from prolonged exposure to a cold environment. Rapid and efficient heating is needed to rewarm the patient from 32-35 degrees C to normal body temperature. Hyperthermia in cancer treatment involves heating malignant tumors to 42.5-43.0 degrees C for an extended period (e.g., 30 min) in an attempt to obtain remission. Microwave or radio frequency heating is often used for rewarming in hypothermia or for temperature elevation in hyperthermia treatment. One severe problem with such heating is the accurate measurement and control of temperature in the presence of a strong electromagnetic field. For this purpose, we have developed a fiberoptic radiometer system which is based on a nonmetallic, infrared fiber probe, which can operate either in contact or noncontact mode. In preliminary investigations, the radiometer worked well in a strong microwave or radiofrequency field, with an accuracy of +/- 0.5 degrees C. This fiberoptic thermometer was used to control the surface temperature of objects within +/- 2 degrees C.