From Images to Shape Models for Object Detection

We present an object class detection approach which fully integrates the complementary strengths offered by shape matchers. Like an object detector, it can learn class models directly from images, and can localize novel instances in the presence of intra-class variations, clutter, and scale changes. Like a shape matcher, it finds the boundaries of objects, rather than just their bounding-boxes. This is achieved by a novel technique for learning a shape model of an object class given images of example instances. Furthermore, we also integrate Hough-style voting with a non-rigid point matching algorithm to localize the model in cluttered images. As demonstrated by an extensive evaluation, our method can localize object boundaries accurately and does not need segmented examples for training (only bounding-boxes).     

Mesh generation for confined fusion plasma simulation

XGC1 and M3D-C ¹ are two fusion plasma simulation codes being developed at Princeton Plasma Physics Laboratory. XGC1 uses the particle-in-cell method to simulate gyrokinetic neoclassical physics and turbulence (Chang et al. Phys Plasmas 16(5):056108, 2009; Ku et al. Nucl Fusion 49:115021, 2009; Admas et al. J Phys 180(1):012036, 2009). M3D-\(C^1\) solves the two-fluid resistive magnetohydrodynamic equations with the \(C^1\) finite elements (Jardin J comput phys 200(1):133–152, 2004; Jardin et al. J comput Phys 226(2):2146–2174, 2007; Ferraro and Jardin J comput Phys 228(20):7742–7770, 2009; Jardin J comput Phys 231(3):832–838, 2012; Jardin et al. Comput Sci Discov 5(1):014002, 2012; Ferraro et al. Sci Discov Adv Comput, 2012; Ferraro et al. International sherwood fusion theory conference, 2014). This paper presents the software tools and libraries that were combined to form the geometry and automatic meshing procedures for these codes. Specific consideration has been given to satisfy the mesh configuration and element shape quality constraints of XGC1 and M3D-\(C^1\).     

The “Always Best Packet Switching” architecture for SIP-based mobile multimedia services

This paper presents a distributed architecture for the provision of seamless and responsive mobile multimedia services. This architecture allows its user applications to use concurrently all the wireless network interface cards (NICs) a mobile terminal is equipped with. In particular, as mobile multimedia services are usually implemented using the UDP protocol, our architecture enables the transmission of each UDP datagram through the “most suitable” (e.g. most responsive, least loaded) NIC among those available at the time a datagram is transmitted. We term this operating mode of our architecture Always Best Packet Switching (ABPS). ABPS enables the use of policies for load balancing and recovery purposes. In essence, the architecture we propose consists of the following two principal components: (i) a fixed proxy server, which acts as a relay for the mobile node and enables communications from/to this node regardless of possible firewalls and NAT systems, and (ii) a proxy client running in the mobile node responsible for maintaining a multi-path tunnel, constructed out of all the node's NICs, with the above mentioned fixed proxy server. We show how the architecture supports multimedia applications based on the SIP and RTP/RTCP protocols, and avoids the typical delays introduced by the two way message/response handshake of the SIP signaling protocol. Experimental results originated from the implementation of a VoIP application on top of the architecture we propose show the effectiveness of our approach.     

Extending the notion of rationality of selfish agents: Second Order Nash equilibria

Motivated by the increasing interest of the Computer Science community in the study and understanding of non-cooperative systems, we present a novel model for formalizing the rational behavior of agents with a more farsighted view of the consequences of their actions. This approach yields a framework creating new equilibria, which we call Second Order equilibria, starting from a ground set of traditional ones. By applying our approach to pure Nash equilibria, we define the set of Second Order pure Nash equilibria and present their applications to the Prisoner’s Dilemma game, to an instance of Braess’s Paradox in the Wardrop model and to the KP model with identical machines.     

AC brushless drive with low-resolution Hall-effect sensors for surface-mounted PM Machines

An ac brushless drive in which Hall-effect sensors are used as rotor position sensors is presented in this paper. Three different methods to obtain a high-resolution position estimation from the low-resolution sensors are described and compared through simulation and experimental testing. The proposed control algorithm's most innovative feature is its adaptability to the entire speed range, including startup, when using any of the three estimation algorithms. The control algorithm has been implemented and tested in order to drive a slotless axial-flux permanent-magnet (PM) machine for domestic appliance applications.     

Methylome Profiling in Fabry Disease in Clinical Practice: A Proof of Concept

Anderson–Fabry disease (FD) is an X-linked disease caused by a functional deficit of the α-galactosidase A enzyme. FD diagnosis relies on the clinical manifestations and research of GLA gene mutations. However, because of the lack of a clear genotype/phenotype correlation, FD diagnosis can be challenging. Recently, several studies have highlighted the importance of investigating DNA methylation patterns for confirming the correct diagnosis of different rare Mendelian diseases, but to date, no such studies have been reported for FD. Thus, in the present investigation, we analyzed for the first time the genome-wide methylation profile of a well-characterized cohort of patients with Fabry disease. We profiled the methylation status of about 850,000 CpG sites in 5 FD patients, all carrying the same mutation in the GLA gene (exon 6 c.901C>G) and presenting comparable low levels of α-Gal A activity. We found that, although the whole methylome profile did not discriminate the FD group from the unaffected one, several genes were significantly differentially methylated in Fabry patients. Thus, we provide here a proof of concept, to be tested in patients with different mutations and in a larger cohort, that the methylation state of specific genes can potentially identify Fabry patients and possibly predict organ involvement and disease evolution.     

A changing society and problems of method: a politically committed research type

This essay examines a politically engaged research genre, which follows the biography of the author who founded two journals: one on mathematical models published in English (Quality and Quantity) and one on politically committed social and economic research published in Italian (Inchiesta). The research considered focuses on Italy in the 1950s, the research by Lazarsfeld in Vienna in the 1920s and in the United States in the 1950s and 1960s, and post-1968 politically committed research in Italy. The analysis of such politically committed types of research (all very different from one another in terms of the interpretative model of reality, the methods used and the relations with the tendering party and the people observed) allows one to understand how this kind of research can be performed with very different methods—all of which do, however, seek to modify reality on the grounds of the research results. The metaphor of the crystal and the flame presented by Italo Calvino in order to classify facts and ideas and styles and feelings can also be used to visualise the polarity (and the difficulty/impossibility of contact) that has always been present in sociology between two different tendencies: towards a discipline that offers the most abstract and objective interpretative model of reality possible with the use of mathematical models (the crystal), and, instead, towards a discipline in which an interpretative model of reality is central, one that produces a social change and in which the qualitative and quantitative methods utilised are at the service of this change (the flame). This polarity thus allows us to separate first and foremost all the politically committed research performed by others for different purposes (market research, research to verify some theoretical hypotheses, etc.) but the same polarity also lies within the politically committed research. We can, indeed, identify a type of politically committed research in an area that has, at one extreme, research tending towards the utmost objectivity and scientific quality of the results and where the co-ordinators try to have all the information on the subjects maintaining the greatest possible distance (the subjects must not know they are being observed); at the other extreme, there is a type of research in which the coordinator completely involves the subjects in the gathering of information that will serve to realise a piece of research whose political aims are explicitly shared. For the identification of a sufficiently articulated typology it has been important to consider five dimensions of politically committed research: (a) the characteristics of the research coordinator (his/her belonging to the type and the academic/non-academic professional status) and his/her interpretative model of reality (b) some general characteristics of the research (the tender and funding, the topic choice, the aims, the contributions to the sociological theory, the duration); (c) the research coordinators relations with the political actors (the intensity of the relations, the political use of the research); (d) the relations of the research co-ordinator with the research subjects; (e) the methodological choices (the basic strategies, the methods used, the use of mathematical procedures). The research that exemplifies this typology is all politically committed to the left and was realised in different times and contexts. I start by considering a kind of politically engaged research (co-research) that appeared in Italy in the 1950s; I then analyse two types of politically engaged research realised in Austria at the end of the 1920s and one in the United States in the 1950s; there then follow two kinds of research realised in the 1960s and 1970s in the United States and a further two kinds realised in Italy in the 1970s and early 1980s. In order to have other kinds of research please refer to the two Journals of which I am the editor: one is an English language journal of mathematical models (Quality and Quantity, International Journal of Methodology, founded in 1966 and published today by Kluwer of Amsterdam), and a politically engaged review (Inchiesta, founded in 1971 and still published today by Dedalo of Bari).     

State-of-the-Art on Wound Vitality Evaluation: A Systematic Review

The vitality demonstration refers to determining if an injury has been caused ante- or post-mortem, while wound age means to evaluate how long a subject has survived after the infliction of an injury. Histology alone is not enough to prove the vitality of a lesion. Recently, immunohistochemistry, biochemistry, and molecular biology have been introduced in the field of lesions vitality and age demonstration. The study was conducted according to the preferred reporting items for systematic review (PRISMA) protocol. The search terms were “wound”, “lesion”, “vitality”, “evaluation”, “immunohistochemistry”, “proteins”, “electrolytes”, “mRNAs”, and “miRNAs” in the title, abstract, and keywords. This evaluation left 137 scientific papers. This review aimed to collect all the knowledge on vital wound demonstration and provide a temporal distribution of the methods currently available, in order to determine the age of lesions, thus helping forensic pathologists in finding a way through the tangled jungle of wound vitality evaluation.     

Extraction of high added value biological compounds from sardine,sardine-type fish and mackerel canning residues — A review

Different valuable compounds, which can be employed in medicine or in other industries (i.e. food, agrochemical, pharmaceutical) can be recovered from by-products and waste from the fish canning industries. They include lipids, proteins, bio-polymers, minerals, amino acids and enzymes; they can be extracted from wastewaters and/or from solid residues (head, viscera, skin, tails and flesh) generated along the canning process, through the filleting, cooking, salting or smoking stages.In this review, the opportunities for the extraction and the valorisation of bioactive compounds from sardine, sardine-type fish and mackerel canning residues are examined and discussed. These are amongst the most consumed fishes in the Mediterranean area; moreover, canning is one of the most important and common methods of preservation. The large quantities of by-products generated have great potentials for the extraction of biologically desirable high added value compounds.     

Clean seas: a North Sea test site

The Clean Seas project focused on the role that existing Earth observing satellites might play in monitoring marine pollution. Results are presented here from August 1997, for the North Sea test site, using sea surface temperature (SST), colour and synthetic aperture radar (SAR) images in conjunction with a hydrodynamic model. There was good correlation between data sources, e.g. between SST and ERS-2 SAR images. Both datasets showed the development of fine plume structures close to the Rhine outflow, apparently associated with the outflow, and possibly caused by tidal pulsing of the Rhine Plume.

The model reproduced general temperature and sediment distributions well, but fine structures were not reproduced. Model sediment distribution patterns were verified using ‘chlorophyll concentration’ data from colour sensors, representative of sediment concentration in turbid water. In conjunction with the visible channels of the Advanced Very High Resolution Radiometer and Along-Track Scanning Radiometer, they give an uncalibrated measure of the sediment load. The model gives a more complete picture of the temporal dispersion of the Rhine Plume over time than is evident from the remotely sensed data alone.