Thyroxine Regulates the Opening of the Organ of Corti through Affecting P-Cadherin and Acetylated Microtubule

Different serum thyroxine levels may influence the morphology of the inner ear during development. A well-developed organ of Corti (OC) is considered to be critical to the function of hearing. In our study, we treated mice with triiodothyronine (T3) and found that the opening of the OC occurred sooner than in control mice. We also observed an increased formation of acetylated microtubules and a decrease in the adhesion junction molecule P-cadherin the during opening of the OC. Our investigation indicates that thyroxin affects P-cadherin expression and microtubule acetylation to influence the opening of the OC.     

Characterization of Two-Component System CitB Family in Salmonella Pullorum

Salmonella enterica, serovar Gallinarum, biovar Pullorum, is an avian-specific pathogen which has caused considerable economic losses to the poultry industry worldwide. Two-component systems (TCSs) play an essential role in obtaining nutrients, detecting the presence of neighboring bacteria and regulating the expression of virulence factors. The genome analysis of S. Pullorum strain S06004 suggesting the carriage of 22 pairs of TCSs, which belong to five families named CitB, OmpR, NarL, Chemotaxis and LuxR. In the CitB family, three pairs of TCSs, namely CitA-CitB, DcuS-DcuR and DpiB-DpiA, remain unaddressed in S. Pullorum. To systematically investigate the function of the CitB family in S. Pullorum, four mutants, ΔcitAB (abbreviated as Δcit), ΔdcuSR (Δdcu), ΔdpiBA (Δdpi) and ΔcitABΔdcuSRΔdpiBA (Δ3), were made using the CRISPR/Cas9 system. The results demonstrated that the CitB family did not affect the growth of bacteria, the results of biochemical tests, invasion and proliferation in chicken macrophage HD-11 cells and the expression of fimbrial protein. But the mutants showed thicker biofilm formation, higher resistance to antimicrobial agents, enhanced tolerance to inhibition by egg albumen and increased virulence in chicken embryos. Moreover, the deletion of Dpi TCS was detrimental to survival after exposure to hyperosmotic and oxidative environments, as well as the long-term colonization of the small intestine of chickens. Collectively, we provided new knowledge regarding the possible role of the CitB family involved in the pathogenic processes of S. Pullorum.     

3种保鲜方式对大平顶枣保鲜效果的影响

以朝阳大平顶枣为原料,研究其在(4±0.3)℃低温条件下,利用氯化钙、迷迭香提取物、热水处理3种常用保鲜方法对大平顶枣采后贮藏特性的影响。通过对大平顶枣的腐烂率、维生素C含量、可滴定酸含量、质构特性的变化以及风味物质检测,比较了不同处理方式对大平顶枣的贮藏保鲜效果。实验结果表明,2.0%氯化钙溶液浸渍、0.2%迷迭香提取物溶液浸渍、45℃热水浸泡均具有很好的保鲜效果。钙盐处理能有效抑制大枣的果皮硬度下降,保持枣果中VC和可滴定酸含量;迷迭香提取物显著(p<0.05)降低了大枣腐烂率,保持枣果VC含量;热水浸泡处理可显著地(p<0.05)提高好果率,延缓鲜果衰老。电子鼻检测的结果表明不同保鲜处理方式下,大枣中的芳香成分的变化速率和规律并不相同,采用线性判别分析(LDA)方法能很好地区分不同新鲜度的大平顶枣。      

葡萄梗(茎)中的生物活性物质研究现状

葡萄梗(茎)是葡萄加工业副产物之一,富含高附加值的生物活性成分,可用于食品、医药和化妆品等工业领域,但较少被人们关注和开发。本文介绍了葡萄梗(茎)中生物活性物质的分布和分离纯化的研究现状,旨在为葡萄生产废弃物葡萄梗(茎)的综合利用提供一定的参考和借鉴。      

Silicon-based inorganic-organic hybrid optoelectronic synaptic devices simulating cross-modal learning

With advances in Si-based technology infrastructures and the rapid integration of Si-based op-toelectronics,Si-based optoelectronic synaptic devices have the po...     

Electrolyte/Structure?Dependent Cocktail Mediation Enabling High?Rate/Low?Plateau Metal Sulfide Anodes for Sodium Storage

As promising anodes for sodium-ion batteries, metal sulfides ubiquitously suffer from low-rate and high-plateau issues, greatly hindering their application in f...     

再生铝合金熔体净化技术的发展现状

开发适合再生铝的熔体净化技术,对提升铝熔体品质是一项极具意义的工作。该技术有助于实现废铝的高效再生与利用,生产高性能的再生铝产品。本文综述了再生铝合金熔体净化技术的发展现状;指出我国铝材料研究的整体水平与国外相比还存在差距,需要进一步加大研发力度以实现超越。     

硅酸锌铁催化臭氧氧化水体中的丙烯酸

本文利用化学共沉淀法制备了硅酸锌铁颗粒催化剂。采用SEM、EDX和XPS等方法对硅酸锌铁催化剂的结构性质和表面组成进行了表征分析。并构建了非均相催化臭氧氧化体系,考察其催化臭氧氧化降解丙烯酸的性能。结果表明在臭氧流量为18 mg/min,催化剂投加量为500 mg/L,催化臭氧氧化反应20 min,丙烯酸的去除率为96.5%。碳酸盐/重碳酸盐实验以及叔丁醇抑制实验证明,在硅酸锌铁催化臭氧氧化过程中有羟基自由基的生成。     

纯铁中磷的高温内耗研究

采用含有不同含量磷的电子轰击纯铁作样品,经脱碳脱氮后,用低频倒扭摆测量其300—800℃之间的内耗值。结果表明,磷含量在0.007—0.28wt%之间的五根样品,分别于580℃和470℃左右出现两个内耗峰,激活能分别为2.13ev和1.80ev。经高温保温一定时期淬火处理后,这两个峰全部消失。由此看出,580℃左右的峰可能是Fe—p的ss峰,而470℃的峰可能是纯铁的PM峰。
本文还研究了一根含稀土元素铈的铁磷合金的内耗。发现在703℃、601℃和500℃相应出现三个内耗峰。初步认为,它们分别是Fe—Ce的ss峰、Fe—P的ss峰和纯铁的PM峰。