Effects of Photodegradable o‐Nitrobenzyl Nanogels on the Photopolymerization Process

A series of partially photodegradable o‐nitrobenzyl nanogels (NBNG) with different caged functional groups (COOH, OH, SH) are prepared and compared with a nondegradable nanogel as additives in photocurable materials. Photoinduced nanogel network disruption and photoinitiated polymerization of infiltrating and dispersing monomer could be controlled independently. In triethylene glycol dimethacrylate (TEGDMA), o‐NBNGs that release a COOH or OH functional group upon photodegradation of the o‐nitrobenzyl crosslinker, the reduced chemical crosslinking density of the nanogel network allows greater penetration of monomer into the partially degraded nanogel network, which results in an increase in volumetric shrinkage and polymerization stress. In contrast, the formulation of o‐NBNGs with caged SH groups also can be photodegraded but is able to rebuild the chemical crosslinking through thiol‐based chain transfer reactions when photocured as a dispersion in TEGDMA. As such, it behaves like a photo‐inert nanogel. Dynamic thermomechanical analysis and testing by three‐point bending further confirms the photoinduced crosslink density variation influences mechanical properties of the final polymer networks. This work demonstrates the inherent properties of the nanogel network and the type of crosslinking can alter the performance of the photocured resin while a separate photochemical process can be used to regulate photoinduced polymerization.     

Quantitative Characterization of Indentation Crack Path in a Cubic Zirconia-10 vol% Alumina Composite

Stereological measurements were performed to characterize the indentation crack path in a cubic zirconia-10 vol% alumina (c-ZrO₂-10 vol% Al₂O₃) composite. Cracks were generated using Vickers indentation, and the crack propagation behavior was characterized as a function of the indentation loading/unloading rates. Cracks that were produced by Vickers indentation formed at higher crack velocities as the loading/unloading rates increased. The amount of contact between the crack and the Al₂O₃ particles increased as the indentation rate decreased. The total number of crack-particle interactions per unit crack length also increased as the indentation rate decreased, because of an increase in the number of particles that were fractured per unit crack length, whereas the number of particles that were debonded remained relatively constant as the indentation rate changed. These results suggest that residual thermal mismatch stresses have predominant control of the crack path at lower crack velocities (low indentation loading/unloading rate), whereas elastic mismatch stresses predominate at higher crack velocities (high indentation loading/unloading rate).     

Oleogels from Glycerol‐Based Lyotropic Liquid Crystals: Phase Diagrams and Structural Characterization

In the course of our studies on structured reverse lyotropic liquid crystals (LLC) as oleogels, a system was designed with the desired physical and rheology properties for cosmetic and pharmaceutical applications. The aqueous phase was partially replaced by glycerol to minimize bacteriological problems and obtain specific rheology characteristics. The constructed phase diagrams are based on ternary mixtures of glycerol monooleate (GMO), decane, water, and glycerol. The main lyotropic mesophase obtained in this study was reverse hexagonal derived from dilution line 8:2 (72 wt% GMO and 18 wt% decane) and 10 wt% water; or water:glycerol (wt ratios 3:1 and 1:1) mixture. It was found that heat‐cool fluctuation caused formation of new pseudo‐equilibrium structures with mesomorphic transformations to more fluid and less ordered mesostructures. Replacing up to 50 wt% of the water by glycerol significantly increases the gel phase region in the phase diagram, meaning more structural compositional options. The structural parameters were determined using cross‐polarized light microscopy (CPLM), differential scanning calorimeter (DSC), powder X‐ray diffraction (PXRD), and small angle X‐ray scattering (SAXS). Rheological measurements revealed viscoelastic properties of lyotropic liquid crystals with a decrease in the elasticity (G′), plasticity (G″), and complex viscosity (η*), as a function of increasing the glycerol content.     

Marital distress and mental health care service utilization.

Objective: This study was designed to evaluate the association between marital distress and mental health service utilization in a population-based sample of men and women (N = 1,601). Method: The association between marital distress and mental health care service utilization was evaluated for overall mental health service utilization and for specific sectors of treatment providers, including psychiatrist, other mental health provider, other medical provider, and religious services provider. Interviews were used to assess past-year service utilization and presence of anxiety, mood, and substance use disorders. Results: Approximately 12% of married individuals sought help for problems with their emotions, nerves, or substance use during the 12 months preceding the interview. Marital distress was significantly associated with (a) overall mental health service utilization and service utilization provided by each of the sectors of providers when controlling for demographic variables and (b) overall mental health service utilization and receiving treatment from a psychiatrist when additionally controlling for past-year anxiety, mood, or substance use disorders. There was little evidence that the associations between marital distress and service utilization were moderated by gender or presence of psychiatric disorders. Conclusion: The finding that marital distress is associated with greater mental health care service utilization suggests that clinicians should assess both individual and relationship factors among individuals presenting for treatment. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

A Human-Robot Collaborative Reinforcement Learning Algorithm

This paper presents a new reinforcement learning algorithm that enables collaborative learning between a robot and a human. The algorithm which is based on the Q(λ) approach expedites the learning process by taking advantage of human intelligence and expertise. The algorithm denoted as CQ(λ) provides the robot with self awareness to adaptively switch its collaboration level from autonomous (self performing, the robot decides which actions to take, according to its learning function) to semi-autonomous (a human advisor guides the robot and the robot combines this knowledge into its learning function). This awareness is represented by a self test of its learning performance. The approach of variable autonomy is demonstrated and evaluated using a fixed-arm robot for finding the optimal shaking policy to empty the contents of a plastic bag. A comparison between the CQ(λ) and the traditional Q(λ)-reinforcement learning algorithm, resulted in faster convergence for the CQ(λ) collaborative reinforcement learning algorithm.     

Dispersed ZrO2 nanoparticles in MCM‐48 with high adsorption activity

A new two‐step synthesis of ZrO₂‐MCM nanocomposites using the gel combustion technique was accomplished; the resulting material had a high‐surface area and showed very high adsorption activity. The deposition of 2–5 nm ZrO₂ particles over MCM was achieved using gel combustion technique with glycine as a fuel, and the formation of nanocomposites was confirmed using transmission electron microscopy. The composites were also characterized by XRD, SEM, FTIR and N₂ adsorption‐desorption analysis. The nanocomposites were tested for the adsorption of cationic dyes. High rates of adsorption and large dye uptake were observed over the nanocomposites. The rate of adsorption over the nanocomposites was higher than that observed for physical ZrO₂‐MCM mixtures and commercial activated carbon. The nanocomposite with 10 wt % ZrO₂ showed the highest rate of adsorption owing to the synergistic effects of ZrO₂ surface groups, smaller particle size, fine dispersion and high‐surface area of the composite. © 2012 American Institute of Chemical Engineers AIChE J, 58: 2987–2996, 2012     

On the Effective Deployment of Functional Formal Verification

We examine IBM's exploitation of formal verification using RuleBase—a formal verification tool developed by the IBM Haifa Research Laboratory. The goal of the paper is methodological. We identify an integrated methodology for the deployment of formal verification which involves three complementary modes: architectural verification, block-level verification, and design exploration.     

Effect of Milling Time on the Rheology of Highly Loaded Aqueous-Fused Silica Slurry

The effects of milling time on the rheological behavior of 70-vol% loaded fused silica slurries were studied. A transition from shear thickening to shear thinning behavior was observed with milling time. Slurry viscosity and thixotropy attained a minimum after 18 h of milling and remained almost unchanged with additional milling. Infrared spectroscopy and particle surface charge measurements confirmed the development of increasing amount of surface hydroxide and surface charge respectively with progress in milling time, leading to shear thinning behavior. An initial static aging treatment of 24 h aided the development of silanol groups, indicating that the milling time can be reduced to save energy and time.     

Kinetics of interaction of HIV fusion protein (gp41) with lipid membranes studied by real-time AFM imaging

One of the most important steps in the process of viral infection is a fusion between cell membrane and virus, which is mediated by the viral envelope glycoprotein. The study of activity of the glycoprotein in the post-fusion state is important for understanding the progression of infection. Here we present a first real-time kinetic study of the activity of gp41 (the viral envelope glycoprotein of human immunodeficiency virus—HIV) and its two mutants in the post-fusion state with nanometer resolution by atomic force microscopy (AFM). Tracking the changes in the phosphatidylcholine (PC) and phosphatidylcholine–phosphatidylserine (PC:PS) membrane integrity over one hour by a set of AFM images revealed differences in the interaction of the three types of protein with zwitterionic and negatively charged membranes. A quantitative analysis of the slow kinetics of hole formation in the negatively charged lipid bilayer is presented. Specifically, analysis of the rate of roughness change for the three types of proteins suggests that they exhibit different types of kinetic behavior.     

Unified representation of fixtures: clamping,locating and supporting elements in CNC manufacture

A CNC machining operation is the outcome of the application of the integrated capabilities of various resources within the CNC machining centre. Part fixtures, clamping and other location mechanisms are essential subsets of CNC machining resources. Today, various fixturing techniques and attachments available in the market allow manufacturers to enhance their production capability without buying expensive machine tools. This technology-rich fixturing domain is detached while representing and exchanging machine tool resource information for making manufacturing decisions. The research work in this article utilises the STEP-NC compliant unified manufacturing resource model (UMRM) for representing fixtures in conjunction with the parent CNC machining centre. Thus, UMRM is enhanced in this context to represent various fixtures such as universal vises, chucks, pallets and auxiliary rotary tables among others. The major contribution of this article is the application of the extension of the UMRM approach for representing fixturing domain, which allows generic modelling of fixtures and loading devices in addition to machine workpiece and process modelling. This would enable the stage of automated process planning and manufacturing. The universal approach in representing resource information allows the data to be utilised for making a wide variety of manufacturing decisions.