Development of passive heat control system for direct methanol fuel cell using electric double layer capacitor

A direct methanol fuel cell (DMFC) is highly anticipated as a new, high‐density energy source for mobile usage; however, its poor power density presents a problem. As a result, the size of portable electronic equipment using DMFCs is far larger than that of equipment using another type of battery. In addition, steady power supply control is difficult, because the output power of the DMFC is affected by the environment. First, this paper presents a pulse charge control system that is a new control system applied to a mobile device, which uses the DMFC and an electric double layer capacitor (EDLC), then describes the new passive heat control and presents experimental results. © 2012 Wiley Periodicals, Inc. Electr Eng Jpn, 179(1): 46–53, 2012; Published online in Wiley Online Library ( wileyonlinelibrary.com ). DOI 10.1002/eej.21129     

Identification of HLA-A24-restricted epitopes with high affinities to Hsp70 using peptide arrays

Heat shock protein 70 (Hsp70) family members are known as facilitators of immune responses by interacting with receptors on antigen-presenting cells leading to Hsp70-peptide uptake and antigen cross priming. Here, identification of human leukocyte antigen (HLA)-A24-restricted epitopes was achieved using peptide arrays for evaluation of their affinities to Hsp70 and HLA-A24 binding prediction tools. Using Hsp70 as the model antigen, the GYPVTNAVI and VFQHGKVEI peptides were identified as antigens. These peptides actually bound to HLA-A24 in the stabilization assay using T2-A*2402 cells, and induced a strong peptide-reactive cytotoxic T lymphocyte response in HLA-A24 transgenic mice after vaccination.     

Development of a maximum‐power‐point‐limiting control system for a direct methanol fuel cell

A new maximum‐power‐point limiting (MPPL) control method for a direct methanol fuel cell (DMFC) was proposed. In regard to achieving MPPL, it was affirmed by experiment that it is possible to control the DMFC by simply ensuring that its voltage does not fall below a certain level regardless of its state. An MPPL control system that accomplishes the DMFC voltage limitation required for MPPL control by using a ‘soft‐start function’ fitted in a ready‐made DC/DC converter was developed. It was confirmed by experimental tests that the circuit board of the developed MPPL control system can perform DMFC voltage limitation control. © 2011 Institute of Electrical Engineers of Japan. Published by John Wiley & Sons, Inc.     

Sonochemical decomposition of perfluorooctane sulfonate and perfluorooctanoic acid

Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) are shown to be globally distributed, environmentally persistent, and bioaccumulative. Although the toxicities of these compounds were reported, the cleanup procedure from the environment is not developed because of their inertness. In this report the sonochemical degradations of PFOS and PFOA to the products through the fission of the perfluorocarbon chains were observed and the half-life times of the PFOS and PFOA degradations under an argon atmosphere determined to be 43 and 22 min, respectively. The shortening of perfluorocarbon chain of PFOS and PFOA leads to the lowering of the toxicity in view of the decrease of the persistence, and the technique would contribute to the remediation of the environmental pollution by these compounds.     

Teleost fish scales: a unique biological model for the fabrication of materials for corneal stroma regeneration

The corneal stroma is composed of multiple lamellae, each containing closely packed collagen fibrils. The orientation of fibrils in a lamella is parallel, but those in different lamellae are orthogonal. As a result, the corneal stroma has a characteristic orthogonal plywood-like structure. Such a highly-regulated three-dimensional arrangement of collagen fibrils gives strength and transparency to the corneal stroma, but it also presents a challenge in the fabrication of materials to replace it. A bioinspired technology is required to process such materials, but the regulatory mechanism of collagen-fibril orientation is still unknown. The low regenerating activity of the corneal stroma seems to be a major factor preventing progress in this field of research. A similarly highly-ordered arrangement of collagen fibrils can be seen in the basal plates of teleost fish scales. Moreover, the scales have high regenerating ability. When a scale is mechanically lost, a new scale is rapidly regenerated. The cells that produce the basal plates are extremely activated; thus, production of the highly-ordered collagen fibrils is very rapid. Therefore, the regenerating scales should be a uniquely helpful biological model for studying the regulatory mechanism of collagen-fibril orientation. Fish-scale collagen has another advantage for use as a biomaterial: the low probability of zoonotic infection. Therefore, scale collagen is a most promising biomaterial for fabricating three-dimensionally arranged collagen fibers to substitute for the corneal stroma. Three tasks that must be clarified for the bioinspired production of a corneal substitute from fish scale collagen are proposed.