东海油田春晓3井凝析气全组分模拟

凝析气相态实验及全组分模拟分析是合理开采凝析气田和提高凝析油采收率的关键。凝析气相态实验分析能直接得出流体的物性参数 ,但并非能测定所有成分的参数。对相态实验不能测定的成分 ,可根据已测参数确定合适的流体相态模型 ,模拟计算出由实验方法不能测定的参数。全组分模拟能精确地模拟不同凝析气藏开采过程中油、气两相组分的瞬间变化、井流物中重组分含量以及一定分离条件下采集到的凝析油量。     

Importance of diabetes mellitus and systemic hypertension rather than completeness of revascularization in determining long-term outcome after coronary balloon angioplasty (the LDCMC registry). Lady Davis Carmel Medical Center

To characterize KC 12291 (1-(5-phenyl-1,2, 4-thiadiazol-3-yl-oxypropyl)-3-[N-methyl-N-[2-(3,4-dimethoxy phenyl) ethyl] amino] propane hydrochloride), a newly synthezised inhibitor of voltage-gated Na+ channels, the effects of the agent on Na+ current and ischemia-induced Na+ overload were investigated in isolated cardiomyocytes, atria and saline-perfused hearts. As measured by the patch clamp technique, KC 12291 (1 microM) significantly reduced peak Na+ current after activation of voltage-gated Na+ channels in rat cardiomyocytes. Partial depolarization enhanced the inhibitory effects during steady state conditions of the channel. In isolated guinea pig atria, 1 microM KC 12291 had no effect on contractility under basal conditions but effectively delayed the onset and reduced the extent of anoxic contracture. The concentration-response curve was clearly shifted to the left when atria were partially depolarized by increased extracellular K+. As measured by 23Na NMR spectroscopy in isolated perfused guinea pig hearts, intracellular Na+ rose more than four-fold in a linear fashion during 60 min of low-flow ischemia. KC 12291 (1 microM) prevented Na+ overload within the initial 12 min of ischemia; thereafter the slope of Na+ accumulation was identical to controls. Electrical excitability of hearts, evaluated by intracardial ECG, completely ceased within 15 min after the onset of ischemia. KC 12291 (1 microM) accelerated this process by more than 6 min. The data provide first evidence that KC 12291 reduces Na+ influx through voltage-gated Na+ channels during ischemia and thus delays Na+ overload by enhancing the inexcitability of the heart.     

A simple linear heuristic for the service constrained random yield problem

We consider the problem of setting order quantities for purchased components subject to uncertainty in the delivery amounts. Assuming the periodic production volumes (demands)to be known and constant, we model this as a random yield problem with the objective of minimizing average inventory cost subject to a service level constraint over the infinite horizon. We first demonstrate that under conditions of random yield, conventional definitions of service can be inappropriate. Then we refine the definition of service for random yield cases and use this to formulate an optimization model. Exact solution of this model proves to be computationally impractical and, as we show, the common heuristic of inflating demands by a constant proportion is not robustly accurate. Therefore, we develop a new heuristic, which we term the linear inflation policy, that specifies a linear function for the inflation factors. Numerical tests indicate that this heuristic can substantially outperform the traditional constant inflation policy and works well relative to a lower bound on the optimal solution on a range of examples.     

Design of Capacitor Bank in Parallel to Photovoltaic Power Plant

The purpose of the paper is to develop a solution for application of PV （photovoltaic） generators in MV （medium voltage） distribution system without unacceptable voltage changes due to drops of PV power output. The proposed solution includes operation of PV with predetermined leading power factor and addition of a capacitor bank in parallel to PV plant in order to compensate the reactive power absorbed by the PV inverters. The analytical expression of required power factor angle is derived. Adding a capacitor bank in parallel to PV power plant may pose a problem because of space limitations. The dimensions and cost of small MV capacitor banks depend significantly on the capacitor bank protection against internal faults. Application of the developed negative-sequence current difference method for the unbalance protection of the capacitor banks enables to achieve a compact and cost-reduced design of the banks connected in parallel to PV power plants. A real-world example of operation of the PV plant in parallel to the capacitor bank with the novel protection scheme is described.     

关于王骏阳常州新项目的二、三事

长兴·秀江南会所是王骏阳的新作。本文不仅试图在中外建筑的广阔语境中对这一作品进行分析,而且也着重阐述了它在现象学层面所呈现出来的空间品质。     

Pharmacokinetics of Single Domain Antibodies and Conjugated Nanoparticles Using a Hybrid near Infrared Method

Iron oxide nanoparticles and single domain antibodies from camelids (VHHs) have been increasingly recognized for their potential uses for medical diagnosis and treatment. However, there have been relatively few detailed characterizations of their pharmacokinetics (PK). The aim of this study was to develop imaging methods and pharmacokinetic models to aid the future development of a novel family of brain MRI molecular contrast agents. An efficient near-infrared (NIR) imaging method was established to monitor VHH and VHH conjugated nanoparticle kinetics in mice using a hybrid approach: kinetics in blood were assessed by direct sampling, and kinetics in kidney, liver, and brain were assessed by serial in vivo NIR imaging. These studies were performed under “basal” circumstances in which the VHH constructs and VHH-conjugated nanoparticles do not substantially interact with targets nor cross the blood brain barrier. Using this approach, we constructed a five-compartment PK model that fits the data well for single VHHs, engineered VHH trimers, and iron oxide nanoparticles conjugated to VHH trimers. The establishment of the feasibility of these methods lays a foundation for future PK studies of candidate brain MRI molecular contrast agents.     

南公1水电站面板堆石坝主堆石区碾压参数试验研究

根据南公1水电站面板堆石坝堆石料碾压参数进行了填筑碾压工艺性试验,分析堆石料的累计沉降量、干密度与碾压遍数和铺料厚度的关系,碾压前后的级配变化,确定了现场施工参数和施工方法,为坝体堆石料填筑碾压施工和质量控制提供了可靠依据.     

搅打稀奶油品质及其影响因素的研究进展

搅打稀奶油是一类可搅打起泡的水包油乳液。作为重要的食品工业原料,搅打稀奶油可作为呈味物质赋予食品良好的感官特性,应用前景广阔。本文首先介绍搅打稀奶油贮藏期内常见的失稳作用,包括乳析、聚集、聚结、部分聚结及奥氏熟化,并阐述界面特性及脂肪球间的交互作如何影响搅打稀奶油的稳定性;其次介绍搅打稀奶油的搅打过程,阐述结晶特性、界面特性和液相蛋白特性如何影响搅打特性。本文可为搅打稀奶油产品的工业化生产提供一定的理论指导。     

基于多源信息融合的核电施工扬尘预测控制算法

为解决在核电施工中雾炮机工作时间过长导致水电资源浪费的问题,以一体化物联网网关为基础,通过多源信息的采集与融合,提出了一种扬尘预测控制算法。该算法根据施工现场和环境情况,从扬尘产生和降尘措施两方面进行量化研究,建立了扬尘预测模型,对扬尘扩散进行预测,并根据预测结果控制雾炮机工作时长,以达到提前降尘和节能的目的。在核电现场进行了对比实验,结果表明,该算法在保障降尘效果基本不变的前提下,节约了60%左右的水电资源。     

Restoration by path concatenation: fast recovery of MPLS paths

A new general theory about restoration of network paths is first introduced. The theory pertains to restoration of shortest paths in a network following failure, e.g., we prove that a shortest path in a network after removing k edges is the concatenation of at most k+1 shortest paths in the original network. The theory is then combined with efficient path concatenation techniques in MPLS (multi-protocol label switching), to achieve powerful schemes for restoration in MPLS based networks. We thus transform MPLS into a flexible and robust method for forwarding packets in a network. Finally, the different schemes suggested are evaluated experimentally on three large networks (a large ISP, the AS graph of the Internet, and the full Internet topology). These experiments demonstrate that the restoration schemes perform well in actual topologies. Received: December 2001 / Accepted: July 2002 RID="*" ID="*" This research was supported by a grant from the Ministry of Science, Israel