STRL33, A novel chemokine receptor-like protein, functions as a fusion cofactor for both macrophage-tropic and T cell line-tropic HIV-1

The chemokine receptors CXCR4, CCR2B, CCR3, and CCR5 have recently been shown to serve along with CD4 as coreceptors for HIV-1. The tropisms of HIV-1 strains for subgroups of CD4(+) cells can be explained, at least partly, by the selective use of G protein-coupled receptors (GPCRs). We have identified a novel human gene, STRL33, located on chromosome 3 that encodes a GPCR with sequence similarity to chemokine receptors and to chemokine receptor-like orphan receptors. STRL33 is expressed in lymphoid tissues and activated T cells, and is induced in activated peripheral blood lymphocytes. When transfected into nonhuman NIH 3T3 cells expressing human CD4, the STRL33 cDNA rendered these cells competent to fuse with cells expressing HIV-1 envelope glycoproteins (Envs). Of greatest interest, STRL33, in contrast with CXCR4 or CCR5, was able to function as a cofactor for fusion mediated by Envs from both T cell line-tropic and macrophage-tropic HIV-1 strains. STRL33-transfected Jurkat cell lines also supported enhanced productive infection with HIV-1 compared with control Jurkat cells. Despite the sequence similarities between STRL33 and chemokine receptors, STRL33-transfected cell lines did not respond to any in a panel of chemokines. Based on the pattern of tissue expression of the STRL33 mRNA, and given the ability of STRL33 to function with Envs of differing tropisms, STRL33 may play a role in the establishment and/or progression of HIV-1 infection.     

中国的三种非同步轨道卫星移动通信系统星座方案

本文介绍基于我国的三种非同步轨道卫星移动通信系统星座方案：低、中轨系统各有２４和１８颗星，轨道高度分别为１３２６和８０３５ｋｍ，两系统各以５°和３０°的仰角对我国的覆盖率为９９．７８％和９９．９６％；椭圆轨道系统１２颗星，近、远地点分别为４２７和２９０６ｋｍ，以７°和１５°仰角对我国北纬２０°以上地区覆盖率分别为９７．９０％和８９．６１％，若增加４颗中轨卫星，以１５°仰角对我国的覆盖率为９９．９９％。     

三峡库区湖北四县水土资源综合开发利用与水土流失防治对策研究

三峡库区湖北宜昌、秭归、兴山、巴东四县幅员面积１１５８９．３平方公里，总人口数１６６．０２万人，三峡水库形成后，淹没土面积７４．４７平方公里，涉及８．９４万人，规划农业生产安置２．８万人。本文以四县土地资源利用现状主和环境容量的分析为基础，进行三峡库区移民安置对水土流失的影响评价，论证综合开发利用水土资源，水土保持与开发性移民相结合，是扩大库区人口环境容量的必由之路，研究制订出移民安置与水土资源的     

The relation between luminous properties and oxygen content inZnS:TbOF thin-film electroluminescent devices fabricated byradio-frequency magnetron sputtering method

The purpose of this paper is to study the relationship between the oxygen concentration and brightness degradation in ZnS:TbOF green thin-film electroluminescent (EL) devices. The characteristics including crystallinity, optical, and electrical properties were discussed. The brightness-voltage (B-V) measurement results shelved that with higher oxygen-content in ZnS:TbOF phosphor layer, lower brightness was measured. It was consistent with the poor crystallinity, worse photoluminescent intensity, and easier to get moisture in the oxygen-rich (O/Tb>1) phosphor film. Furthermore, deep level transient spectroscopy (DLTS) measurements identified that when the O/Tb ratio was greater than 1, the oxygen-related deep hole traps E_H1 and/or E_H2 could be detected in the ZnS:TbOF phosphor layer. These E _H1 and/or E_H2 traps were believed to be the main killers for the brightness of the device since they capture most of the holes from the generated electron-hole pairs. This evidence strongly supports that the modified energy transfer model is more dominant than direct impact excitation during the luminescent process     

二阶A型Cooper变换的增强型

对二阶Ａ型Ｃｏｏｐｅｒ变换进行增强，放宽可用性条件，并证明了其正确性，最后举例说明其应用。     

Full Or-Parallemism and Restricted And-Parallelism in BTM

BTM is a new And/Or parallel execution model for logic programs which exploits both full Or-parallelism and restricted And-parallelism.The advantages of high parallelism and low run time cost make BTJ,an experimental execution system of BTM implemented on a nonshared-memory multiprocessor system,achieve significant speedup for both And-paralled and Or-parallel logic programs.     

试论企业人格化管理的力量因素

论述了影响企业人格化管理的力量因素，并指出制度纪律是其保障因素，道德规范是其自律因素，理想目标是其进取因素。     

Mass transfer kinetics of neodymium(III) extraction by calix[4]arene carboxylic acid using a constant interfacial area cell with laminar flow

BACKGROUND: Thermodynamics and kinetics data are both important to explain the extraction property. In order to develop a novel separation technology superior to current extraction systems, many promising extractants have been developed including calixarene carboxylic acids. The extraction thermodynamics behavior of calix[4]arene carboxylic acids has been reported extensively. In this study, the mass transfer kinetics of neodymium(III) and the interfacial behavior of calix[4]arene carboxylic acid were investigated. RESULTS: The rate constant (K_ao) becomes constant when the stirring speed was controlled between 250 rpm and 400 rpm. The activation energy (E_a) was calculated to be 21·41 kJ mol^?1 or 88·17 kJ mol^?1 (dependent on temperature) from the slope of log K_ao against 1000/T. The linear relationship between the specific area and the extraction rate is the characteristic of an interfacial reaction control. The minimum bulk concentration of the extractant necessary to saturate the interface (C_min) is lower than 4·19 × 10^?4 mol L^?1. CONCLUSION: The effect of stirring speed, temperature, and species concentration on the extraction rate demonstrates that the extraction regime depends on the extraction conditions. The chemical reaction control governs the extraction regime at temperatures below 303 K and a mixed control regime occurs when the temperature is between 303 K and 318 K. The probable locale for the chemical reaction is at the liquid–liquid interface and the rate equation is deduced to be: ? d[Nd³⁺]_(a)/dt = k_f[Nd³⁺]_(a)[H₄A]_(o)^0·727[H⁺]_(a)^?0·978. The rate‐controlling step was suggested by the analysis of the experimental results. Copyright © 2008 Society of Chemical Industry     

以不同PAN系炭纤维布制备燃料电池气体扩散层之研究

采用石墨化PAN系炭纤维布制备了高分子电解质燃料电池气体扩散层。通过电学实验、X-ray绕射与元素分析考察了所制气体扩散层的性能。结果表明：随热处理温度的升高，气体扩散层的电阻率降低，L2增加，d（x）2减小。高温处理后的炭纤维布作为高分子电解质燃料电池气体扩散层显示了较高的电池效能。     

自由口通信模式下计算机读写PLC存储区的程序设计

本文介绍了在自由口通信模式下，用计算机读写S7—200PLC存储区内相邻的多个字节数据的通信程序设计方法，程序设计中采用了多种可靠性措施。