A Hemispherical Image Sensor Array Fabricated with Organic Photomemory Transistors

Hemispherical image sensors simplify lens designs, reduce optical aberrations, and improve image resolution for compact wide-field-of-view cameras. To achieve hemispherical image sensors, organic materials are promising candidates due to the following advantages: tunability of optoelectronic/spectral response and low-temperature low-cost processes. Here, a photolithographic process is developed to prepare a hemispherical image sensor array using organic thin film photomemory transistors with a density of 308 pixels per square centimeter. This design includes only one photomemory transistor as a single active pixel, in contrast to the conventional pixel architecture, consisting of select/readout/reset transistors and a photodiode. The organic photomemory transistor, comprising light-sensitive organic semiconductor and charge-trapping dielectric, is able to achieve a linear photoresponse (light intensity range, from 1 to 50 W m⁻²), along with a responsivity as high as 1.6 A W⁻¹ (wavelength = 465 nm) for a dark current of 0.24 A m⁻² (drain voltage = −1.5 V). These observed values represent the best responsivity for similar dark currents among all the reported hemispherical image sensor arrays to date. A transfer method was further developed that does not damage organic materials for hemispherical organic photomemory transistor arrays. These developed techniques are scalable and are amenable for other high-resolution 3D organic semiconductor devices.     

Contribution of various substrates to total citric acid cycle flux and ]anaplerosis as determined by13C isotopomer analysis and O2 consumption in the heart

A simple relationship between parameters derived from a¹³C NMR isotopomer analysis and O₂ consumption is presented that allows measurement of the absolute rate of acetyl-CoA oxidation and anaplerotic flux in tissues oxidizing a mixture of four substrates. The method was first applied in a study of the effects of work state and -adrenergic stimulation on net acetate oxidation and anaplerosis in the isolated working rat heart. The results demonstrate that the anticipated ratio of 2 between O₂ consumption and TCA cycle flux for hearts oxidizing only acetate holds at low workload when anaplerosis is low, but deviates toward a factor of 3 under high workload conditions when anaplerosis is increased. This analysis was also extended to hearts that oxidize a more physiological mixture of substrates including long-chain fatty acids, acetoacetate, lactate, pyruvate, and glucose. We show that the contribution each substrate makes to total TCA cycle flux can be determined by combined¹³C NMR and O₂ consumption measurements. The present study also demonstrates that stimulation of anaplerosis (by addition of propionate) can significantly alter the relative contribution each substrate makes to total TCA cycle flux. We conclude that if¹³C labeling patterns are selected appropriately, a comprehensive picture of flux through all major metabolic pathways feeding the cycle can be determined in a single experiment even when complex physiological mixtures of substrates are provided.     

Data-delay evaluation in integrated wireless networks based on local product-form solutions for voice occupancy

In this paper we consider the evaluation of data-packet delay in wireless integrated voice/data networks. In networks that support voice in the classical circuit-switched fashion, the voice occupancy process satisfies a product-form solution under reasonable modeling assumptions. Although this product-form solution provides an accurate characterization of equilibrium voicetraffic behavior, it does not directly provide a method to evaluate data-packet delay. However, examination of each link separately in a manner that incorporates interaction with the rest of the network permits us to take advantage of the wireless nature of the network and obtain a three-flow characterization of each link, which also satisfies a product-form solution and is hence termed a mini-product-form solution. By matching the values of these flows to the average values obtained from the product-form solution of the entire network, we obtain a three-dimensional Markov chain characterization of the voice occupancy state on the link, which permits a simpler evaluation of data-packet delay. A further reduction is possible by converting the three-dimensional chain to a single-dimensional one. Performance results demonstrate that these models provide satisfactory delay estimates that also appear to be upper bounds on delay.C.M. Barnhart was at the Naval Research Laboratory when this paper was written.     

Silverlight在交互式出图系统中的应用

随着工程设计出图中用户对交互性和体验感的要求越来越高,传统的以数据为中心,以HTML为表现形式的Web出图系统已远不能满足用户更高的、全方位的体验要求,而RIA及微软Silverlight技术平台的出现正好为这个问题提供了很好的解决途径。文章重点介绍了如何通过微软的Silverlight技术来设计和实现高体验度的交互式出图系统。     

Development of quantitative structure-activity relationships for explanatory modeling of fast reacting (meth)acrylate monomers bearing novel functionality

The photoinitiated polymerization of (meth)acrylate monomers bearing novel carbamate functionality exhibits significantly greater reaction rate when compared to more traditional acrylate monomers undergoing similar polymerization. This unusually fast reactivity has been the subject of much investigation. In order to suggest an explanatory mechanism for the enhanced polymerization rates we have conducted quantitative structure-activity relationship investigations of these novel monomers. These studies have resulted in statistically sound models with coefficients of multiple determination of R(2)>0.93. Principal component and k nearest neighbor similarity analysis were also conducted on the multiple regression models. These results are discussed in light of published experimental investigations of the photopolymerization reactivity of the novel monomers.     

Adaptive relaxation for querying heterogeneous XML data sources

Searching XML data with a structured XML query can improve the precision of results compared with a keyword search. However, the structural heterogeneity of the large number of XML data sources makes it difficult to answer the structured query exactly. As such, query relaxation is necessary. Previous work on XML query relaxation poses the problem of unnecessary computation of a big number of unqualified relaxed queries. To address this issue, we propose an adaptive relaxation approach which relaxes a query against different data sources differently based on their conformed schemas. In this paper, we present a set of techniques that supports this approach, which includes schema-aware relaxation rules for relaxing a query adaptively, a weighted model for ranking relaxed queries, and algorithms for adaptive relaxation of a query and top-k query processing. We discuss results from a comprehensive set of experiments that show the effectiveness and the efficiency of our approach.     

Corrective classification: Learning from data imperfections with aggressive and diverse classifier ensembling

Learning from imperfect (noisy) information sources is a challenging and reality issue for many data mining applications. Common practices include data quality enhancement by applying data preprocessing techniques or employing robust learning algorithms to avoid developing overly complicated structures that overfit the noise. The essential goal is to reduce noise impact and eventually enhance the learners built from noise-corrupted data. In this paper, we propose a novel corrective classification (C2) design, which incorporates data cleansing, error correction, Bootstrap sampling and classifier ensembling for effective learning from noisy data sources. C2 differs from existing classifier ensembling or robust learning algorithms in two aspects. On one hand, a set of diverse base learners of C2 constituting the ensemble are constructed via a Bootstrap sampling process; on the other hand, C2 further improves each base learner by unifying error detection, correction and data cleansing to reduce noise impact. Being corrective, the classifier ensemble is built from data preprocessed/corrected by the data cleansing and correcting modules. Experimental comparisons demonstrate that C2 is not only more accurate than the learner built from original noisy sources, but also more reliable than Bagging [4] or aggressive classifier ensemble (ACE) [56], which are two degenerated components/variants of C2. The comparisons also indicate that C2 is more stable than Boosting and DECORATE, which are two state-of-the-art ensembling methods. For real-world imperfect information sources (i.e. noisy training and/or test data), C2 is able to deliver more accurate and reliable prediction models than its other peers can offer.     

Process and learning outcomes from remotely-operated,simulated, and hands-on student laboratories

A large-scale, multi-year, randomized study compared learning activities and outcomes for hands-on, remotely-operated, and simulation-based educational laboratories in an undergraduate engineering course. Students (N = 458) worked in small-group lab teams to perform two experiments involving stress on a cantilever beam. Each team conducted the experiments in one of three lab formats (hands-on, remotely-operated, or simulation-based), collecting data either individually or as a team. Lab format and data-collection mode showed an interaction, such that for the hands-on lab format learning outcomes were higher when the lab team collected data sets working as a group rather than individually collecting data sets to be combined later, while for remotely-operated labs individual data collection was best. The pattern of time spent on various lab-related activities suggests that working with real instead of simulated data may induce higher levels of motivation. The results also suggest that learning with computer-mediated technologies can be improved by careful design and coordination of group and individual activities.