守望春天

2004年12月22日，北京降下了这一年的首场大雪，整个北京城银装素裹。与此同时，人民大会堂里热气腾腾，中国室内设计学会成立15周年的庆典正在举行。作为个新型的学会，中国室内设计学会发展的进程紧紧跟随着我国改革开放和经济发展的步伐，我们用了二十年的时间达到了别的国家上百年时间才能达到的规模。中国室内设计学会已经逐步走入它的辉煌时代，正呈现着副朝气蓬勃的春天景象。     

Considerations and strategies behind the design and construction requirements of the Istanbul Strait immersed tunnel

This being a design-build project, the challenge faced during preparations of the Employer’s requirements for design and construction of the Istanbul Strait immersed tunnel was to give the contractor as much freedom as possible and yet specify enough so that the Employer obtained the required facility. When completed, this will be a world-class facility. This paper discusses on a strategic level many of the aspects to be presented by the author in two papers in later sessions of the day. Unusual features of this crossing include the deepest ever immersed tunnel crossing, extra waterproofing requirements, strong currents with bi-directional flow, close proximity of the North Anatolian Fault which is predicted to have a major seismic event during the life of the tunnel, and the method of connecting the adjacent bored tunnels to the immersed tunnel. Safety during tunnel construction and operation has been paramount, and resulted in changes to contract packaging and extra requirements. Other challenges discussed include fish migration, control of an international waterway, environmental issues and ensuring the stability of the soft soils during a seismic event.     

公共娱乐场所消防安全现状及对策

从消防安全管理的角度,论述了公共娱乐场所消防安全存在的主要问题和如何进一步加强公共娱乐场所的消防安全工作     

Atomic force microscopic analysis of hydrogen peroxide bleached kraft northern black spruce fibres

Hydrogen peroxide is a potent, relatively inexpensive oxidant that chemically degrades chromophoric components in pulps and textiles. Oxidation of cellulose is a byproduct of this process step that decreases the tensile strength of individual fibres. The residence time of pulp in the bleaching reactor must be optimized to achieve the desired brightness and minimizing fibre degradation. To evaluate the impact of peroxide bleaching at the microfibrillar level, a single black spruce tree was chosen and kraft pulped. Peroxide bleaching was conducted via benchtop polyethylene bag bleaching in a temperature-controlled waterbath. Atomic force microscopy (AFM) topographical images acquired before and after the bleaching step show dramatic changes in fibre structure consistent with delignification and defects in the surface topography. This was further verified by X-ray work at Brookhaven National Laboratory, NY, U.S.A.     

Chitosan particles agglomerated scaffolds for cartilage and osteochondral tissue engineering approaches with adipose tissue derived stem cells

In the XML file of the original article, H. Redl’s affiliation is incorrect. It is listed correctly in both the paper and PDF versions of the article, and can be found below: The online version of the original article can be found at     

Mammalian Rh/T2/S-glycoprotein ribonuclease family genes: cloning of a human member located in a region of chromosome 6 (6q27) frequently deleted in human malignancies

OBJECTIVE: To implement a low-cost system of transmitting high-quality digital photographs of mutilating extremity injuries using the speed of the Internet. DESIGN: A high-resolution digital camera and simple hardware and software platform are used to take and transmit images via electronic mail. The images are received within minutes by the consultant, and an assessment can be made. RESULTS: A low-cost and high-quality system can easily be implemented. Images can be seen by consultants only a few minutes after they are obtained. The quality of the reproductions is excellent, and they are handled exactly as other photographs. CONCLUSION: This technique can be widely applicable and inexpensive to initiate in any emergency room. It allows rapid assessment of extremity injuries and x-ray images by expert consultants, who can then evaluate the replantation or revascularization potential of extremity trauma cases. This can eliminate unnecessary and often expensive transfer of patients who are not candidates for replantation.     

Detection of human papillomavirus gene sequences in laryngeal tumors and premalignant changes by polymerase chain reaction

Human papillomavirus gene sequences have been detected in a number of malignant and benign tumours. Non-oncogenic types 6 and 11 are etiological factors of benign mucosal tumours. Types 16 and 18 can be detected in malignancies most often but their role in the etiopathogenesis of cancers is still unclear. In our study we examined formalin-fixed and paraffin-embedded archive laryngeal tissues containing squamous cell carcinoma, papilloma and precancerous lesions for the presence of human papillomavirus genes. As a control we also examined tissues harbouring laryngeal nodules which represented the normal larynx in our study. After DNA preparation from the paraffin blocks we performed polymerase chain reaction to detect the DNA of human papillomavirus types 6, 11, 16 and 18. In the squamous cell carcinomas, papillomas and precancerous lesions the presence of human papillomavirus gene sequences was significantly higher than in the control group. To verify the integrity of DNA we also amplified a sequence deriving from the cellular beta-globin gene. Based on the 100% positivity for this gene we declare that the combination of our DNA preparation and polymerase chain reaction is a reliable method for detecting DNA sequences from formalin-fixed and paraffin-embedded tissues.     

Use of the nuclear microprobe at the University of Arizona for the study of heavy metal deposition in rabbit renal tissue

Industrial wastes consigned to disposal sites frequently contain substantial amounts of heavy metals. We have successfully applied proton induced X-ray emission analysis (PIXE) in the conduct of heavy metal (Hg, Cd, Cr, As) toxicity studies using precision cut rabbit renal cortical slices. The large beam diameter (4000 μm) of the proton macroprobe at The University of Arizona Ion Beam Analysis facility allowed an overall concentration of the metal(s) of interest in the samples to be determined, but lacked the ability to resolve point concentrations in the tissue. The ability to locate these areas has now been made available to us with the addition of a rastering microprobe (μ-PIXE) to the facility. Studies now being conducted in our laboratory using this micro-technique include analysis of renal tissue taken from rabbits injected intraperitoneally with HgCl₂, K₂Cr₂O₇, and NaAsO₂. The small beam size (3 μm) and the ability to raster this beam over areas of up to 125 μm × 125 μm has allowed regional mapping of endogenous and non-endogenous metal concentrations and revealed trends in heavy metal deposition in in vivo treated renal tissue, significantly increasing the amount of information obtained from these animal studies using PIXE alone. The combination of small beam size, high resolution, and multi-element detection makes μ-PIXE a powerful tool for investigating the impact of non-endogenous metals on the kidney.