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排序方式: 共有473条查询结果,搜索用时 15 毫秒
431.
Gas holdup and surface‐liquid mass transfer rate in a bubble column have been experimentally investigated. De‐mineralized water, 0.5 and 1.0% aqueous solutions of carboxy methyl cellulose (CMC), and 60% aqueous propylene glycol have been used as the test liquids. Effects of column diameter, liquid height to column diameter ratio, superficial gas velocity and liquid phase viscosity on gas holdup and mass transfer rate are studied. Generalized correlations for the average gas holdup and wall to liquid heat and mass transfer coefficients are proposed. These are valid for both Newtonian and pseudoplastic non‐Newtonian fluids. 相似文献
432.
Sandeep Kumar Reddy Adena Mansi Upadhyay Harsh Vardhan 《Drug development and industrial pharmacy》2018,44(3):493-501
Objective: The purpose of this research study was to develop, optimize, and characterize dasatinib loaded polyethylene glycol (PEG) stabilized chitosan capped gold nanoparticles (DSB-PEG-Ch-GNPs).Methods: Gold (III) chloride hydrate was reduced with chitosan and the resulting nanoparticles were coated with thiol-terminated PEG and loaded with dasatinib (DSB). Plackett–Burman design (PBD) followed by Box–Behnken experimental design (BBD) were employed to optimize the process parameters. Polynomial equations, contour, and 3D response surface plots were generated to relate the factors and responses. The optimized DSB-PEG-Ch-GNPs were characterized by FTIR, XRD, HR-SEM, EDX, TEM, SAED, AFM, DLS, and ZP.Results: The results of the optimized DSB-PEG-Ch-GNPs showed particle size (PS) of 24.39?±?1.82?nm, apparent drug content (ADC) of 72.06?±?0.86%, and zeta potential (ZP) of ?13.91?±?1.21?mV. The responses observed and the predicted values of the optimized process were found to be close. The shape and surface morphology studies showed that the resulting DSB-PEG-Ch-GNPs were spherical and smooth. The stability and in vitro drug release studies confirmed that the optimized formulation was stable at different conditions of storage and exhibited a sustained drug release of the drug of up to 76% in 48?h and followed Korsmeyer–Peppas release kinetic model.Conclusions: A process for preparing gold nanoparticles using chitosan, anchoring PEG to the particle surface, and entrapping dasatinib in the chitosan-PEG surface corona was optimized. 相似文献
433.
434.
Grinding of Ti-6Al-4V Under Small Quantity Cooling Lubrication Environment Using Alumina and MWCNT Nanofluids 总被引:1,自引:0,他引:1
Ti-6Al-4V is a difficult-to-grind material as chips tend to adhere to the grit materials of an abrasive wheel due to its chemical affinity. In the present work, it has been attempted to improve the grindability by application of small quantity cooling lubrication (SQCL) technology using nanofluids, namely, multiwalled carbon nanotube (MWCNT) and alumina nanofluid. The suitability of nanofluids was experimentally evaluated in reciprocating surface grinding using a vitrified SiC wheel. Substantial improvement in grindability under the influence of MWCNT nanofluid (SQCL) could be achieved compared to soluble oil (flood). Reduction of specific grinding forces and specific energy was observed due to the combined effect of superior heat dissipation and lubrication abilities; when the latter one was realized through on-site rolling of MWCNT strands, inter-tubular slip and solid lubrication of the film adhered onto the wheel surface. These outperforming characteristics of MWCNT nanofluid helped in retaining grit sharpness superiorly, thus resulting in better surface finish and less re-deposition of metal on the ground workpiece. On the contrary, Al2O3 nanofluid (SQCL) underperformed even soluble oil (flood). For an ageing effect, Al2O3 nanoparticles resulted in abrasive agglomerates, which led to its failure, despite its good heat dissipation capability. 相似文献
435.
436.
Abhinav Vishnu Shuaiwen Song Andres Marquez Kevin Barker Darren Kerbyson Kirk Cameron Pavan Balaji 《The Journal of supercomputing》2013,63(3):691-709
As the march to the exascale computing gains momentum, energy consumption of supercomputers has emerged to be the critical roadblock. While architectural innovations are imperative in achieving computing of this scale, it is largely dependent on the systems software to leverage the architectural innovations. Parallel applications in many computationally intensive domains have been designed to leverage these supercomputers, with legacy two-sided communication semantics using Message Passing Interface. At the same time, Partitioned Global Address Space Models are being designed which provide global address space abstractions and one-sided communication for exploiting data locality and communication optimizations. PGAS models rely on one-sided communication runtime systems for leveraging high-speed networks to achieve best possible performance. In this paper, we present a design for Power Aware One-Sided Communication Llibrary – PASCoL. The proposed design detects communication slack, leverages Dynamic Voltage and Frequency Scaling (DVFS), and Interrupt driven execution to exploit the detected slack for energy efficiency. We implement our design and evaluate it using synthetic benchmarks for one-sided communication primitives, Put, Get, and Accumulate and uniformly noncontiguous data transfers. Our performance evaluation indicates that we can achieve significant reduction in energy consumption without performance loss on multiple one-sided communication primitives. The achieved results are close to the theoretical peak available with the experimental test bed. 相似文献
437.
Navneet Upadhyay Hamurabi Gamboa Rosales 《International Journal of Speech Technology》2016,19(4):869-880
Speech recognizers achieve high recognition accuracy under quiet acoustic environments, but their performance degrades drastically when they are deployed in real environments, where the speech is degraded by additive ambient noise. This paper advocates a two phase approach for robust speech recognition in such environment. Firstly, a front end subband speech enhancement with adaptive noise estimation (ANE) approach is used to filter the noisy speech. The whole noisy speech spectrum is portioned into eighteen dissimilar subbands based on Bark scale and noise power from each subband is estimated by the ANE approach, which does not require the speech pause detection. Secondly, the filtered speech spectrum is processed by the non parametric frequency domain algorithm based on human perception along with the back end building a robust classifier to recognize the utterance. A suite of experiments is conducted to evaluate the performance of the speech recognizer in a variety of real environments, with and without the use of a front end speech enhancement stage. Recognition accuracy is evaluated at the word level, and at a wide range of signal to noise ratios for real world noises. Experimental evaluations show that the proposed algorithm attains good recognition performance when signal to noise ratio is lower than 5 dB. 相似文献
438.
Static or motionless mixers have received wide application in chemical and allied industries due to their low cost and high efficiency. The pressure drop and mixing behaviour of such mixers have been widely studied. However, the available information for non‐Newtonian fluids is scanty. The results of pressure drop and mixing studies conducted with a locally made motionless mixer (MALAVIYA mixer) and four non‐Newtonian fluids—aq. CMC, PVA, and PEG solutions are reported in this article. The new mixer causes less pressure drop compared to some of the commercial mixers. Mixing behaviour of the unit is more closer to plug flow and a two‐parameter model correlates the dispersion data. 相似文献
439.
Paolo Piraino Vivek K. Upadhyay Rocco Rossano Paolo Riccio Eugenio Parente Alan L. Kelly Paul L.H. McSweeney 《Food chemistry》2007,101(3):964-972
A rapid method for characterizing proteolysis in different cheese varieties was developed using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-ToF-MS). pH 4.6-soluble extracts of different cheese varieties were sub-fractionated using ethanol and 70% ethanol-soluble extracts were analyzed using MALDI-ToF-MS. Sample analysis time was ∼3 min compared to ∼100 min for reversed-phase HPLC; moreover, the method yielded accurate molecular masses of peptides originating as a result of proteolysis. Small peptides (<3500 m/z) were monitored and data for relative intensities of peptides were analyzed using multidimensional scaling (MDS) to demonstrate the similarity between profiles obtained from different cheese varieties. The similarities between the profiles of MALDI-ToF mass spectra were demonstrated in a two-dimensional space by performing MDS on the similarity matrix. Use of MALDI-ToF-MS is thus a fast and effective method for monitoring small peptides produced in cheese as a result of proteolysis. 相似文献
440.
Thomas W. Custer Kuruthachalam Kannan Lin Tao Abhinav R. Saxena Bill Route 《Journal of Great Lakes research》2009
In 2007 archived great blue heron (Ardea herodias) eggs collected from Indiana Dunes National Lakeshore, IN, (Indiana Dunes) in 1993 were analyzed for 11 perfluorinated compounds (PFCs) and 7 polybrominated diphenyl ethers (PBDEs). Concentrations of perfluorooctane sulfonate, the major contributor to total PFC concentrations, were below the toxicity thresholds estimated for bobwhite quail (Colinus virginianus) and mallards (Anas platyrhynchos), but within the toxicity threshold estimated for white leghorn chickens (Gallus domesticus). The ranking of PBDE congener concentrations by percent concentration (PBDE-47 > -99 > -100 > -153 > -154 > -28 > -183) was consistent with the Penta-PBDE formulation. Total PBDE concentrations in great blue heron eggs from Indiana Dunes were elevated and probably reflect local contamination from highly urbanized and industrialized inputs into Lake Michigan. Polybrominated diphenyl ether concentrations were within levels associated with altered reproductive behavior in other avian species and based on trends in other Great Lakes birds are probably higher today. 相似文献