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101.
Alina Jakób Jolanta BryjakHalina Wójtowicz Viera IlleováJúlius Annus Milan Polakovič 《Food chemistry》2010
Ohmic heating of milk and fruit and vegetable juices was carried out at several incubation temperatures to investigate inactivation of alkaline phosphatase, pectin methylesterase and peroxidase. Mechanisms of inactivation of these enzymes and corresponding kinetic models were verified for each food material, using the multitemperature evaluation of inactivation data. Compared to inactivation by conventional indirect heating, kinetic parameters were changed but inactivation mechanisms remained the same. The kinetic parameter changes were relatively minor for pectin methylesterase and alkaline phosphatase. A significant destabilization of the labile isozyme fraction of peroxidase occurred by the effect of ohmic heating when the greatest decrease of stability was obtained for carrot juice. 相似文献
102.
103.
Beata Kaczmarek Kinga Nadolna Agata Owczarek Olha Mazur Alina Sionkowska Krzysztof ukowicz Jithin Vishnu Geetha Manivasagam Anna M. Osyczka 《IET nanobiotechnology / IET》2020,14(9):830
Scaffolds based on chitosan (CTS), collagen (Coll) and glycosaminoglycans (GAG) mixtures cross‐linked by tannic acid (TA) with bioglass 45S5 addition were obtained with the use of the freeze‐drying method. The prepared scaffolds were characterised for morphology, mechanical strength and degradation rate. Moreover, cell viability on the obtained scaffolds was measured with and without the presence of ascorbic acid and dexamethasone. The main purpose of the research was to compare the effectiveness of bioglass 45S5 influence on the physicochemical and biological properties of scaffolds. The results demonstrated that the scaffolds based on the blends of biopolymers cross‐linked by TA are stable in an aqueous environment. Scanning electron microscope images allowed the observation of a porous scaffold structure with interconnected pores. The addition of bioglass nanoparticles improved the mechanical properties and decreased the degradation rate of composite materials. The biological properties were improved for 20% tannic acid addition compared to 5%. However, the addition of bioglass 45S5 did not change to cells response significantly.Inspec keywords: biomedical materials, drying, porous materials, freezing, tissue engineering, proteins, nanofabrication, bone, scanning electron microscopy, polymers, molecular biophysics, cellular biophysics, nanoparticles, porosityOther keywords: chitosan, collagen, glycosaminoglycans, bioglass 45S5 addition, freeze‐drying method, degradation rate, ascorbic acid, dexamethasone, physicochemical properties, biological properties, porous scaffold structure, bioglass nanoparticles, mechanical properties, tannic acid addition, scanning electron microscopy 相似文献
104.
Joanna Kulikowska Agnieszka Kulczyska-Przybik Barbara Mroczko Alina Kuakowska 《International journal of molecular sciences》2021,22(11)
SARS-CoV-2/Coronavirus 2019 (COVID-19) is responsible for the pandemic, which started in December 2019. In addition to the typical respiratory symptoms, this virus also causes other severe complications, including neurological ones. In diagnostics, serological and polymerase chain reaction tests are useful not only in detecting past infections but can also predict the response to vaccination. It is now believed that an immune mechanism rather than direct viral neuroinvasion is responsible for neurological symptoms. For this reason, it is important to assess the presence of antibodies not only in the serum but also in the cerebrospinal fluid (CSF), especially in the case of neuro-COVID. A particular group of patients are people with multiple sclerosis (MS) whose disease-modifying drugs weaken the immune system and lead to an unpredictable serological response to SARS-CoV-2 infection. Based on available data, the article summarizes the current serological information concerning COVID-19 in CSF in patients with severe neurological complications and in those with MS. 相似文献
105.
Poly(acrylonitrile-co-N-isopropylacrylamide) (p(AN-co-NIPAM)) core-shell hydrogel nanoparticles were synthesized by microemulsion polymerization and their feasibility as a drug carrier was investigated. Highly monodispersed nanoparticles with desired size range - i.e., 50-150 nm - were prepared by adjusting the reaction conditions. The hydrophobic core of the composite which consists primarily of poly(acrylonitrile), can be easily made highly hydrophilic by converting the nitrile groups to the corresponding amidoxime groups. This provides a level of tunability in the hydrophobicity/hydrophilicity balance of the composite nanoparticle. The thermo-responsive feature of the shell was utilized for the release of a model drug, propranolol (PPL). It is shown that the loading/release capacity of nanoparticles was increased almost two-fold by the amidoximation of the core material. 相似文献
106.
Simona Liliana Iconaru Alina Mihaela Prodan Mikael Motelica-Heino Stanislas Sizaret Daniela Predoi 《Nanoscale research letters》2012,7(1):576
The aim of this study was to obtain saccharide (dextran and sucrose)-coated maghemite nanoparticles with antibacterial activity. The polysaccharide-coated maghemite nanoparticles were synthesized by an adapted coprecipitation method. X-ray diffraction (XRD) studies demonstrate that the obtained polysaccharide-coated maghemite nanoparticles can be indexed into the spinel cubic lattice with a lattice parameter of 8.35 Å. The refinement of XRD spectra indicated that no other phases except the maghemite are detectable. The characterization of the polysaccharide-coated maghemite nanoparticles by various techniques is described. The antibacterial activity of these polysaccharide-coated maghemite nanoparticles (NPs) was tested against Pseudomonas aeruginosa 1397, Enterococcus faecalis ATCC 29212, Candida krusei 963, and Escherichia coli ATCC 25922 and was found to be dependent on the polysaccharide type. The antibacterial activity of dextran-coated maghemite was significantly higher than that of sucrose-coated maghemite. The antibacterial studies showed the potential of dextran-coated iron oxide NPs to be used in a wide range of medical infections. 相似文献
107.
Michael K. Hausmann Alina Hauser Gilberto Siqueira Rafael Libanori Signe Lin Vehusheia Simone Schuerle Tanja Zimmermann Andr R. Studart 《Small (Weinheim an der Bergstrasse, Germany)》2020,16(1)
Responsive materials with birefringent optical properties have been exploited for the manipulation of light in several modern electronic devices. While electrical fields are often utilized to achieve optical modulation, magnetic stimuli may offer an enticing complementary approach for controlling and manipulating light remotely. Here, the synthesis and characterization of magnetically responsive birefringent microparticles with unusual magneto‐optical properties are reported. These functional microparticles are prepared via a microfluidic emulsification process, in which water‐based droplets are generated in a flow‐focusing device and stretched into anisotropic shapes before conversion into particles via photopolymerization. Birefringence properties are achieved by aligning cellulose nanocrystals within the microparticles during droplet stretching, whereas magnetic responsiveness results from the addition of superparamagnetic nanoparticles to the initial droplet template. When suspended in a fluid, the microparticles can be controllably manipulated via an external magnetic field to result in unique magneto‐optical coupling effects. Using a remotely actuated magnetic field coupled to a polarized optical microscope, these microparticles can be employed to convert magnetic into optical signals or to estimate the viscosity of the suspending fluid through magnetically driven microrheology. 相似文献
108.
The new OPC Unified Architecture has been introduced as a replacement for the existing COM‐based specifications. The article describes a generalized algorithm for the automatic generation of the address space structure for an UA server. First, we present the general startup procedure of an OPC UA server, focusing on the address space generation step. Afterwards we introduce specialized algorithms for the generation of the type nodes, of object, variable, method and view nodes. Finally the additional references are added to the fully meshed address space. The basic ideas of the algorithms are: the splitting of the nodes into groups and the sequential addition of the groups to the address space, and the naming of a main reference for every target node. The algorithms have been applied for an aggregating UA server which models the devices of an assembly line. The main advantages are: shorter development time, easier maintenance and the possibility to add nodes to the address space in both online and offline mode. Copyright © 2011 John Wiley & Sons, Ltd. 相似文献
109.
The electrical conductivity is an important property of nanofluids that has not been widely studied. To study both the effects of temperature and concentration, the electrical conductivity of water-based Al2O3 nanofluids with 12?nm diameter particles is measured. Conventional models, such as the Maxwell model and Bruggemann correlation, were considered for comparison and disagreement were noticed. Experimental results showed the Al2O3 nanofluids increased their electrical conductivity with increasing volume fraction as compared to that of the base fluid, as well as with temperature increasing. A stronger influence on volume fraction was noticed. Electrical conductivity measurements for these nanofluids indicate an enormous enhancement (390.11?%) at 60?°C for a volume fraction of 4?%in distilled water. Furthermore, at higher volume fractions, the electrical conductivity enhancement begins to level off, which is attributed to ion condensation effects in the high-surface charge regime. A 3D statistical analysis was also considered to obtain an empirical correlation. 相似文献
110.
Maria Elena Zarif Saa Alexandra Yehia Bogdan Bi Veronica Stulu Sorin Vizireanu Gheorghe Dinescu Alina Maria Holban Florica Marinescu Ecaterina Andronescu Alexandru Mihai Grumezescu Alexandra Ctlina Bîrc Alexandru Titus Farcaiu 《International journal of molecular sciences》2021,22(23)
Despite the technological progress of the last decade, dental caries is still the most frequent oral health threat in children and adults alike. Such a condition has multiple triggers and is caused mainly by enamel degradation under the acidic attack of microbial cells, which compose the biofilm of the dental plaque. The biofilm of the dental plaque is a multispecific microbial consortium that periodically develops on mammalian teeth. It can be partially removed through mechanical forces by individual brushing or in specialized oral care facilities. Inhibition of microbial attachment and biofilm formation, as well as methods to strengthen dental enamel to microbial attack, represent the key factors in caries prevention. The purpose of this study was to elaborate a cold plasma-based method in order to modulate microbial attachment and biofilm formation and to improve the retention of fluoride (F−) in an enamel-like hydroxyapatite (HAP) model sample. Our results showed improved F retention in the HAP model, which correlated with an increased antimicrobial and antibiofilm effect. The obtained cold plasma with a dual effect exhibited through biofilm modulation and enamel strengthening through fluoridation is intended for dental application, such as preventing and treating dental caries and enamel deterioration. 相似文献