Physical chemistry of flavour

The sensation of flavour occurs when certain flavour-active molecules are released from food and are transported to stimulate sensors in the mouth and nose. The human brain integrates all the signals from the sensors and produces an overall flavour perception. The way in which flavour molecules are released from food during eating, and the manner in which they are retained during processing and storage, are all governed by various aspects of physical chemistry. This review describes some of the basic principles of partition, a key parameter in the physical chemistry of flavour. An overview of the theory and measurement of partition is given, along with some applications to model and real food systems.     

Lexical and sublexical translation of spelling to sound: Strategic anticipation of lexical status.

Two experiments on oral reading of single words compared naming performance in pure blocks of nonwords or exception words with performance in blocks of randomly mixed nonwords and exception words. Ss named exception words faster and made fewer regularization errors when they were not also prepared for nonwords. These data suggest Ss inhibit or ignore the computation of assembled phonology when only exception words are expected. Ss named nonwords faster, but no more accurately, when low-frequency exception words were not also anticipated. Thus, Ss' readiness to execute assembled phonology appears to be adjusted in relation to the likely time course of retrieval of learned pronunciations, when the latter must be attended to. This evidence for strategic dissociation between sublexical and lexical translation is discussed in relation to current models. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Modelling of electrostatic gate operations in the Kane solid state quantum computer

The nuclear spin quantum computer proposed by Kane [Nature 393 (1998) 133] exploits as a qubit array ³¹P dopants embedded within a silicon matrix. Single-qubit operations are controlled by the application of electrostatic potentials via a set of metallic ‘A’ gates, situated above the donors, on the silicon surface, that tune the resonance frequency of individual nuclear spins, and a globally applied RF magnetic field that flips spins at resonance. Coupling between qubits is controlled by the application of potentials via a set of ‘J’ gates, between the donors, that induce an electron-mediated coupling between nuclear spins. We report the results of the study of the electric field and potential profiles arising within the Kane device from typical gate operations. The extent to which a single nuclear spin can be tuned independently of its neighbours, by operation of an associated A-gate, is examined and key design parameters in the Kane architecture are addressed. Implications for current fabrication strategies involving the implantation of ³¹P atoms are discussed. Solution of the Poisson equation has been carried out by simulation using a TCAD modelling package (Integrated Systems Engineering AG).     

Semi-global stabilization of minimum phase nonlinear systems in special normal forms

We semi-globally stabilize certain minimum phase nonlinear systems which are in a normal form where the nonlinear subsystem is driven by an output of a linear system that possesses (possibly) nonzero peaking exponents. We eliminate the peaking phenomenon by stabilizing part of the linear system with a high-gain linear control and part of the linear system with a small, bounded control. The interpretation of this approach will be that we are redefining the outputs to add asymptotically stable nonlinear zeros to the system in a manner that allows the new composite zero dynamics to be asymptotically stable on arbitrarily large compact sets.     

Plastic ball grid array (PBGA) overview

As integrated circuit functionality and clock speed continue to rise, innovative packaging approaches are in great demand. Recently, the plastic ball grid array (PBGA) technology has been gaining industry-wide interest and commitment as the potentially lowest-cost package for high-I/O devices and even for some lower-pincount applications. Drivers include the density advantages of an area array, quickly achieving six-sigma assembly yields with existing assembly equipment, the potential for excellent electrical and thermal performance, along with the traditional low cost of plastic packages. Because some perceived weaknesses are being eradicated, worldwide evaluation of the PBGA has accelerated. Although various aspects of this technology are discussed frequently, an overall assessment is still under development. In this paper, a systematic and comprehensive evaluation of PBGA technology will be described to identify (1) its technical advantages and limitations, (2) unique application areas where PBGA is the package of choice, and (3) current major hurdles for acceptance of PBGA and possible approaches to overcome these problems. The PBGA will be compared with PQFP, CQFP and CBGA in terms of package characteristics and their impact on system assembly. The characteristics include package attributes (i.e., package size, I/O counts and lead pitch), performance (i.e., electrical, thermal) and reliability (moisture). At the system level, solder joint fatigue, board routing, solder assembly yield, solder reparability and board delay are key metrics. The cost implication of various package families will be discussed. By analogy with SMT, the infrastructure for PBGA will take time to develop. The key elements and the current status of this infrastructure will be discussed.     

Importance of biotic interactions in large rivers: an experiment with planktivorous fish,dreissenid mussels and zooplankton in the St. Lawrence River

Physical conditions are usually considered pre‐eminent in controlling river plankton, but biotic interactions may be important in slackwater areas. To begin testing this general hypothesis, we conducted a 12‐day, predator–prey experiment in 3500 litre mesh enclosures in a slackwater area of the St. Lawrence River using planktivorous, juvenile yellow perch (Perca flavescens) and Dreissena mussels. Results generally supported our hypotheses that: (1) perch would directly suppress large zooplankton via predation but benefit microzooplankton through indirect interactions; and (2) dreissenids would directly depress rotifer densities via predation and have indirect negative effects on macrozooplankton. Based on gut contents of experimental fish, cladocera were the principal prey of smaller yellow perch (c. 46–50 mm), followed by copepods, ostracods, and rotifers. Larger juvenile perch (c. 67–73 mm) fed almost exclusively on copepods and ostracods. Densities of calanoid copepodids, nauplii, and some cyclopoid copepods (Diacyclops thomasi) were significantly depressed by perch, and adult Eurytemora affinis (99% of adult calanoids) essentially disappeared from fish enclosures. Despite being a favourite prey item of small perch, densities of the small cladoceran Bosmina (Sinobosmina) spp. were significantly higher when fish were present (150% greater than control densities on Day 12). Densities of the very abundant rotifer Polyarthra were >300% greater in fish enclosures than controls by Day 12, and the rotifers Synchaeta and predaceous Ploesoma were significantly more abundant in the presence of perch. Increases in rotifers and cladocera suggest indirect, positive effects of fish related to significantly higher phytoplankton biomass or decreased densities of predaceous copepods. Densities of eight of ten zooplankton groups examined declined significantly when mussels were present, and calanoid copepodids also declined but not significantly. Chlorophyll‐a concentrations were slightly lower in mussel enclosures. This evidence suggests biotic interactions play important roles among potamoplankton in slackwater habitats, but river‐wide implications of these findings require further study. Copyright © 2003 John Wiley & Sons, Ltd.     

Automatic laser shutdown implications for all optical data networks

Generalized multiprotocol label switching (GMPLS), optical packet, and burst-switched networks in which the synchronous digital hierarchy/synchronous optical network (SDH/SONET) layer is removed may be rendered nonfunctional because the current standard for triggering Automatic Power Reduction (APR) cannot distinguish between a fiber that has been de-energized and a fiber failure. If this standard is applied, without modification, the likelihood of unnecessary amplifier shutdown in optical networks is significant. These shutdown events may impact large regions of the network and render optical links inoperable. To avoid unnecessary amplifier shutdown, amendments to the current operation of APR are suggested.     

Homocysteine and cognitive impairment; a case series in a General Practice setting

Background  

An elevated blood level of homocysteine is a risk factor for cognitive impairment and dementia. Homocysteine can be lowered by folate and/or vitamin B₁₂ supplementation; antioxidants might also be required for optimal reduction in neurovascular tissue. This report presents clinical and radiological findings from administering the antioxidant N-acetylcysteine together with B vitamins to cognitively impaired patients with hyperhomocysteinaemia.     

Quantitation of Ink Transferred During Pharmaceutical Printing Operations Using Inductively Coupled Plasma Atomic Emission Spectroscopy

The identification of solid dosage forms is often achieved through printing with a non-toxic ink. Due to product purity requirements, a method to quantify the amount of ink applied to tablets and capsules is of interest to the pharmaceutical industry.

The following presentation investigated the use of inductively coupled plasma atomic emission spectroscopy (ICP-AES) as a direct method of quantifying the amount of ink on a tablet. Because the ink used contained an iron oxide pigment of known composition, quantitation of the iron content could be used to measure the amount of ink transferred to the tablet.

The quantitative results obtained using ICP-AES were in agreement with calculated values for the volume of ink in the gravure roll. Tablets exposed to “double printing” were easily detected by the ICP-AES method.     

Biogeochemical Evaluation of Mechanisms Controlling CaCO3(s) Precipitation in Landfill Leachate-Collection Systems

A common failure mode for landfills is clogging of the leachate-collection system. The reduction in hydraulic conductivity associated with clogging causes a buildup of leachate head on the underlying liner, potentially increasing advective contaminant transport from the landfill and contaminating adjacent groundwater. In this paper, the biogeochemical model CCBATCH is used to link a primary cause of leachate collection system failure—CaCO3(s) precipitation?to anaerobic degradation of volatile fatty acids (VFAs) in column reactors used to study the clogging phenomena. One key to applying CCBATCH correctly was dividing the VFA conversion into two steps: conversion of propionate to acetate, carbonic acid, and methane; and acetate conversion to methane and carbonic acid. The primary driver for CaCO3(s) precipitation in the columns was acetate fermentation to CH4 and H2CO3, which increased the total carbonate concentration in the leachate and shifted the acid/base control to a weaker acid system, which caused an increase in solution pH. A second key to proper modeling was adding CO2(g) gas transfer to CCBATCH. The modeling results indicate that the kinetics of CO2(g) gas transfer was a key control over leachate chemistry once acetate fermentation was nearly complete. These results suggest that the best approach for the long-term control of CaCO3(s) clogging may be to enhance CO2(g) gas transfer from the leachate while buffering the leachate pH to near neutral. Taken together, these actions should decrease the yield of CaCO3(s) precipitated per mass of acetate removed.