Psychological differentiation and psychotherapy

Patient's level of psychological differentiation was studied in relation to patients' and therapists' evaluations of the initial psychotherapy session. The evaluations assessed two broad dimensions of the interaction which generally have been considered important for psychotherapeutic success and which have been found to be related to patients' psychological differentiation: namely, patients' and therapists' satisfaction with the amount of structure, and therapists' impressions of patients' appropriateness for therapy. Significant correlations were obtained between patients' psychological differentiation and both of these dimensions. However, two control variables, socioeconomic status and alcohol use, were also found to be related to these dimensions. When the effects of these variables were partialed out, the relationships with therapists' impressions of appropriateness disappeared, but the relationships with patients' and therapists' satisfaction with the amount of structure remained significant. The relationship of these findings to other studies of psychological differentiation and psychotherapy is discussed. Finally, the contribution of the present results to the choice of the most appropriate measure of psychological differentiation is noted.     

Structure-activity relationship of new 2-substituted penem antibiotics

The antibacterial activities of three new penems with 4-hydroxyprolinamide, 1-prolinamide and N-methyl-N-2-propionamide substituents, respectively, in position 2 and of their stereoisomers were examined against Staphylococcus aureus, Enterococcus faecalis, Enterococcus faecium, Escherichia coli and Pseudomonas aeruginosa. All substitutes conferred a broad antibacterial spectrum on the penem moiety. Changes in stereoisomerism selectively improved the activity against E. coli, S. aureus or enterococci. The structure-activity relationships of each compound were discussed in relation to minimum inhibitory concentrations, penicillin-binding protein (PBP) affinity and outer membrane permeability coefficient in E. coli. In this microorganism, PBP 2 was the target for all compounds. Changes in stereoisomerism influenced the affinity for PBPs 1A/B and 2. All antibiotics easily permeated the outer membrane of E. coli and, within each group of compounds, the penetration rate correlated with the antibacterial activity.     

Epilepsy and disorders of cortical development in children with congenital cytomegalovirus infection

INTRODUCTION: Neuroimaging and experimental studies have related cytomegalovirus (CMV) to certain neuronal migration disorders. MATERIAL AND METHODS: To define the electroclinical picture of children with epilepsy associated with disorders of cortical development (DCD) and congenital CMV infection, we conducted a clinical, electroencephalographic and neuroradiological study of 10 children with this condition. RESULTS: Eighty per cent of them had dismorphic traits, or malformations outside CNS. All showed other neuroradiological signs (cerebral calcification, white matter damage, porencephaly). Six patients with bihemispheric DCD (agyria-pachigyria, 2; 'poligyria', 1; schizencephaly, 1; bilateral opercular DCD, 2) showed: Tetraparesis, severe or profound mental deficiency, early onset epilepsy (mean age at onset: 11 months) with spasms, tonic seizures, partial seizures, and multifocal paroxysms or unusual diffuse sharp Alfa-Beta EEG activity. One child developed Epilepsia Partialis Continua. Children with bilateral opercular DCD evolved to a continuous spike and wave (SW) electrical status during wakefulness and sleep, linked to a worsening of psychomotor derangement. Four patients with unilateral hemispheric DCD (pachigyric or 'poligyric') showed: Congenital hemiparesis, mild intellectual deficiency, motor seizures (orofacial, hemiclonic, generalized) beginning in the third year of live, atypical absences with focal phenomena, frequent focal rhythmic SW discharges during wakefulness, and continuous SW status during sleep (CSWS). CONCLUSIONS: A wide spectrum of DCD due to congenital CMV infection is documented. Characteristic electroclinical pictures related to the extent and topographical distribution of the DCD are recognized, which may lead to an appropriate diagnosis and prognosis.     

Characterization of superconducting thin films by Mo75Re25 target for rf cavity applications

superconducting thin films by Mo₇₅Re₂₅ single-target magnetron sputtering at various temperatures on sapphire substrates were prepared. Sharp superconductive transitions andT _c values above 10 K were achieved, and the deposited films showed a good metallic behavior. According to structural analyses (EDS and X-rays), all the samples have the same stoichiometry as the target and, even at low deposition temperatures, they exhibit theA15 phase. From measured residual resistivities and superconducting critical temperatures the theoretical BCS surface resistances were estimated and compared to those o Mo₆₀Re₄₀ films, presented in a previous work. Both these alloys, in fact, being characterized by low surface resistances and high critical fields, are good candidates as coating films in r.f. cavities.     

The Luria-Nebraska Neuropsychological Battery: Theoretical orientation and comment.

Since the introduction of the Luria-Nebraska Neuropsychological Battery (LNNB), issues related to its understanding, interpretation, and validity have generated much interest. In response to P. A. Spiers's (see record 1981-24833-001) criticism of the battery, the authors suggest that the controversy appears to arise from a divergence in theoretical orientation on the role of quantitative versus qualitative assessment as well as from differences in the understanding of measurement methodology and validity. The present article discusses the theoretical basis from which the LNNB was constructed and describes the process of test interpretation. Previous and current research on use and validity of the battery is presented as it relates to the theoretical and methodological concerns. While basic philosophical differences with other theoretical systems are not likely to be resolved, the authors of the LNNB will continue to emphasize the integration of quantitative and qualitative approaches, both in the use of the LNNB and in the field of neuropsychology in general. It is concluded that the LNNB will continue to be revised on the basis of research findings and experience with the test in different patient populations. (35 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The flow of a viscoelastic fluid past a porous plate

Summary The flow of a second order viscoelastic fluid past a porous plate is considered. It is characterized by a boundary value problem in which the order of the differential equation exceeds the number of available boundary conditions. The boundary value problem is solved by making a plausible assumption, namely that the variation of the normal derivative of the velocity at the plate withk is sufficiently smooth, wherek is the viscoelastic fluid parameter. Under this assumption it is shown that dual solutions exist for values ofk less than a critical value. Beyond this value, no solution exists.     

Petrological and geochemical mass-balance equations: an algorithm for least-square fitting and general error analysis

Least-square fitting of petrological and geochemical overdetermined linear systems is carried out by means of a rapidly converging algorithm which allows a general treatment of coefficient uncertainties. Both constrained and unconstrained solutions are presented. The modal analysis of lunar rock 10022 and stoichiometric coefficients for two coronitic reactions are so determined, as an example, from application of the proposed procedure to available chemical analyses.