全文获取类型
收费全文 | 199669篇 |
免费 | 2307篇 |
国内免费 | 613篇 |
专业分类
电工技术 | 3468篇 |
综合类 | 149篇 |
化学工业 | 28960篇 |
金属工艺 | 8049篇 |
机械仪表 | 6068篇 |
建筑科学 | 4811篇 |
矿业工程 | 1303篇 |
能源动力 | 5127篇 |
轻工业 | 17115篇 |
水利工程 | 2298篇 |
石油天然气 | 4040篇 |
武器工业 | 8篇 |
无线电 | 23066篇 |
一般工业技术 | 40012篇 |
冶金工业 | 37228篇 |
原子能技术 | 5086篇 |
自动化技术 | 15801篇 |
出版年
2021年 | 1605篇 |
2019年 | 1568篇 |
2018年 | 2573篇 |
2017年 | 2645篇 |
2016年 | 2775篇 |
2015年 | 1794篇 |
2014年 | 3074篇 |
2013年 | 8939篇 |
2012年 | 5050篇 |
2011年 | 7021篇 |
2010年 | 5589篇 |
2009年 | 6350篇 |
2008年 | 6443篇 |
2007年 | 6511篇 |
2006年 | 5579篇 |
2005年 | 5229篇 |
2004年 | 5005篇 |
2003年 | 4887篇 |
2002年 | 4525篇 |
2001年 | 4656篇 |
2000年 | 4578篇 |
1999年 | 4726篇 |
1998年 | 11374篇 |
1997年 | 8120篇 |
1996年 | 6408篇 |
1995年 | 4673篇 |
1994年 | 4271篇 |
1993年 | 4073篇 |
1992年 | 3223篇 |
1991年 | 3076篇 |
1990年 | 2870篇 |
1989年 | 2951篇 |
1988年 | 2826篇 |
1987年 | 2398篇 |
1986年 | 2308篇 |
1985年 | 2715篇 |
1984年 | 2505篇 |
1983年 | 2345篇 |
1982年 | 2090篇 |
1981年 | 2203篇 |
1980年 | 2029篇 |
1979年 | 2124篇 |
1978年 | 2120篇 |
1977年 | 2366篇 |
1976年 | 3188篇 |
1975年 | 1833篇 |
1974年 | 1761篇 |
1973年 | 1772篇 |
1972年 | 1443篇 |
1971年 | 1339篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
51.
B Antonsson DB Kassel G Di Paolo R Lutjens BM Riederer G Grenningloh 《Canadian Metallurgical Quarterly》1998,273(14):8439-8446
SCG10 is a neuron-specific, membrane-associated protein that is highly concentrated in growth cones of developing neurons. Previous studies have suggested that it is a regulator of microtubule dynamics and that it may influence microtubule polymerization in growth cones. Here, we demonstrate that in vivo, SCG10 exists in both phosphorylated and unphosphorylated forms. By two-dimensional gel electrophoresis, two phosphoisoforms were detected in neonatal rat brain. Using in vitro phosphorylated recombinant protein, four phosphorylation sites were identified in the SCG10 sequence. Ser-50 and Ser-97 were the target sites for protein kinase A, Ser-62 and Ser-73 for mitogen-activated protein kinase and Ser-73 for cyclin-dependent kinase. We also show that overexpression of SCG10 induces a disruption of the microtubule network in COS-7 cells. By expressing different phosphorylation site mutants, we have dissected the roles of the individual phosphorylation sites in regulating its microtubule-destabilizing activity. We show that nonphosphorylatable mutants have increased activity, whereas mutants in which phosphorylation is mimicked by serine-to-aspartate substitutions have decreased activity. These data suggest that the microtubule-destabilizing activity of SCG10 is regulated by phosphorylation, and that SCG10 may link signal transduction of growth or guidance cues involving serine/threonine protein kinases to alterations of microtubule dynamics in the growth cone. 相似文献
52.
A process-inherent NAND2 device is presented for a three-dimensional CMOS integration with epitaxial lateral overgrowth and chemo-mechanical polishing. The required 'OR' function of the two PMOS transistors is achieved by one silicon volume, which is controlled by a back gate and a conventional front gate. Almost symmetrical characteristics are measured for the front and the back gates.<> 相似文献
53.
Auld B.A. Chimenti D.E. Shull P.J. 《IEEE transactions on ultrasonics, ferroelectrics, and frequency control》1996,43(2):319-325
The transverse resonance approach to guided wave analysis is applied to shear horizontal (SH) wave propagation in periodically layered composites. It is found for SH waves that at high values of the guided wavevector β, the wave energy is trapped in the slower of the two media and propagates accordingly at the slower wavespeed. At low values of β, however, the modes demonstrate a clustering behavior, indicative of the underlying Floquet wave structure. The number of modes in a cluster is observed to correlate with the number of unit cells in the layered plate. New physical insights into the behavior of these systems are obtained by analyzing the partial waves of the guided SH modes in terms of Floquet waves. We show that the fast and slow shear waves in the periodically layered composite play an analogous role to the longitudinal and shear partial waves comprising Lamb waves in a homogeneous plate 相似文献
54.
K Alanko L Kanerva B Mohell-Talolahti R Jolanki T Estlander 《Canadian Metallurgical Quarterly》1996,35(4):647-648
The biotransformation of oxazepam by Bifidobacterium bifidum was studied. The major metabolite was purified by chromatographic methods and found to be desmethyldiazepam using NMR, IR and other physicochemical data. 相似文献
55.
Maher M. Osman Mounir M. Abd El-Malek Aida B. Tadros Atef M. Michael 《Journal of chemical technology and biotechnology (Oxford, Oxfordshire : 1986)》1995,62(1):46-52
4-Amino-3-thio-1,24-triazolidine (L1) and 4-amino-5-thio-1,3,4-thiadiazole (LII) as well as their metal complexes of the general formulae MLI·2H2O and MLIICl (M; Pb(II), Cd(II) and Zn(II)) were prepared. With Sn(II), we obtained Sn(LI)2·2H2O and SnLIICl, respectively. The structures of the compounds were identified through elemental analysis, and IR and UV spectra measurements, in addition to thermal analysis in case of the metal complexes. The antifouling properties of the compounds were tested by their incorporation into paint formulations which were applied to PVC substrates and tested in water from Alexandria western harbour. When the compounds were added at 17·5% by volume, the coated panels were fouled after 3 months of immersion. The addition of 6·7% by volume of tributyltin oxide to 15·8% of the prepared compounds in one formulation elevated the paint efficiency and prevented fouling for 11 months. Paint containing solely tributyltin oxide at the same concentration was inactive against algae. 相似文献
56.
57.
Lewis Gloria J.; Greenburg Sharon L.; Hatch David B. 《Canadian Metallurgical Quarterly》1988,19(1):81
We report the results of the first national survey of psychologists in private practice regarding their participation in peer consultation groups. The sample (71% return) was drawn from 800 randomly selected psychologists listed in the National Register of Health Service Providers in Psychology. We found that 23% of the sample currently belonged to peer consultation groups, and 24% had belonged in the past. Of those not currently in groups, 61% expressed the desire to belong if one were available. There were virtually no significant demographic differences between current members and nonmembers. We examined the following group characteristics: formation, length of existence, size, membership, leadership, theoretical orientation, range of experience, time and place, content, and group process. Groups tended to be small, informal, and leaderless; however, we found great variation among groups on all dimensions. Findings also showed a high degree of satisfaction with membership. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
58.
B Hull 《Canadian Metallurgical Quarterly》1997,26(6):18-19
Two hundred and fifteen patients with pulmonary involvement of lobar (regional, segmental) extent were examined. The examination procedure included clinical and laboratory tests, X-ray tomographic study, and computed tomography, bronchoscopy with biopsy, cyto- and histological studies. The nosological diagnosis was established in 96.5% of cases. Differential diagnosis was found to be difficult in 3.5% of cases. 相似文献
59.
B Amblard C Assaiante JC Fabre L Mouchnino J Massion 《Canadian Metallurgical Quarterly》1997,114(2):214-225
The ability voluntarily to stabilize the head in space during lateral rhythmic oscillations (0.59+/-0.09 Hz) of the trunk has been investigated during microgravity (microG) and normal gravity (nG) conditions (parabolic flights). Five healthy young subjects, who gave informed consent, were examined. The movements were performed with eyes open or eyes closed, during phases of either microG or nG. The main result was that head orientation with respect to vertical may be stabilized about the roll axis under microG with, as well as without vision, despite the reduction in vestibular afferent and muscle proprioceptive inputs. Moreover, the absence of head stabilization about the yaw axis confirms that the degrees of freedom of the neck can be independently controlled, as was previously reported. These results seem to indicate that voluntary head stabilization does not depend crucially upon static vestibular afferents. Head stabilization in space may in fact be organized on the basis of either dynamic vestibular afferents or a short-term memorized postural body schema. 相似文献
60.
H Neudeck M Joncic C Schuster S Bisson R Hildebrandt T Oney B Stiemer H Hopp R Graf 《Canadian Metallurgical Quarterly》1997,37(6):449-458
Nitric oxide (NO) acts as a modulator of neuronal transmission in mature neuronal systems, including the retina. Recently, NO has also been suggested to have a trophic function during development. We examined immunocytochemically the distribution of NO-producing cells in developing and transplanted rabbit retinas. An antibody detecting the neuronal isoform of its biosynthetic enzyme, nitric oxide synthase (NOS), was used on normal developing retinas [starting at embryonic day (E) 15] and on rabbit retinal transplants after various survival times (1-139 days after surgery). Weakly stained cell bodies were first observed in the proximal margin of the neuroblastic layer at E 29. Stained processes projecting towards a developing inner plexiform layer were also visible at this time point. Immunoreactive cells were located at later stages in the innermost part of the inner nuclear layer and in the ganglion cell layer, and are likely to correspond mainly to amacrine cells. NOS-labelled cells were also found in retinal transplants. The first NOS-labelled cells appeared, as in normal developing retinas, in ages corresponding to E 29 and were still detected in transplants corresponding to postnatal day 123. NOS-labelled cells were seen in areas between rosettes, where amacrine cells are located. NOS-labelled processes were at times seen to project for long distances, forming very distinct plexuses. NOS-containing amacrine cells thus appear both in the transplants and in developing retinas in the embryonic stages, long before synaptic function involving these cells can be expected, suggesting a role for NO not only in neuromodulation but also in retinal development. 相似文献